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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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DTSTART:20240331T010000
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DTSTART;TZID=Europe/Paris:20240619T110000
DTEND;TZID=Europe/Paris:20240619T110000
DTSTAMP:20260311T220925
CREATED:20240528T153355Z
LAST-MODIFIED:20240612T174151Z
UID:171877-1718794800-1718794800@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Keisuke Yonehara
DESCRIPTION:Venue: CARF (ex CGFB) \n\nKeisuke Yonehara\nNational Institute of Genetics\, Mishima\, Japan \nInvited by Naoya Takahashi (IINS) \nTitle\nDiverse neural activity in the mouse superior colliculus \nAbstract\nThe mouse superior colliculus receives retinal input from most retinal ganglion cells and translates visual signals into visually guided innate behaviors such as hunting\, escape\, and orientation. To understand how these unique functions are implemented in the neural circuits of the superior colliculus\, my laboratory studies the diversity of neural activity in response to different light stimuli and behavioral conditions. To do so\, we combine in vivo two-photon imaging from head-fixed mice\, miniscope imaging from freely moving mice\, genetic labeling of cell types\, and transsynaptic viral tracking. Today\, I will discuss our latest findings on 1) how many functional cell types exist (Schwartz et al.\, bioRxiv 2023) and 2) how neurons respond to self-motion in the mouse superior colliculus. \n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-keisuke-yonehara/
CATEGORIES:For scientists,home-event,Impromptu seminar
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DTSTART;TZID=Europe/Paris:20240619T110000
DTEND;TZID=Europe/Paris:20240619T110000
DTSTAMP:20260311T220925
CREATED:20240531T072834Z
LAST-MODIFIED:20240604T104422Z
UID:171944-1718794800-1718794800@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Gisella Vetere
DESCRIPTION:Venue: Centre Broca \n\nGisella Vetere\nCerebral codes and Circuits Connectivity team (C4 team)\, Brain Plasticity Unit\, ESPCI PSL Paris (France) \nhttps://veterelab.weebly.com \nInvited by Jeremy Lesas (Herry’s team) \nTitle\nDissection of a memory engram to understand how associative memories are formed \nAbstract\nWhen an associative memory is formed? Which cells represent memories\, and when are they engaged? In my laboratory\, we are interested inn understanding memory formation and consolidation. To this aim we use techniques to visualize and tag cells with unprecedented temporal precision\, to unravel their role in processing specific information present at the time of encoding. I will first show the possibility to implant fully artificial memories in mice just by optogenetically targeting codes the brain uses to process external information. I will then present new data from my lab where we identified non-overlapping dorsal CA1 neuronal ensembles that are differently active during associative fear memory acquisition. These ensembles disproportionately contribute to fear engram formation This study revealed\, for the first time\, the unique contribution of cells active at specified time points to the formation of a memory trace. \nSelection of publications\n1. Casanova JP\, Pouget C\, Treiber N\, Agarwal I\, Brimble MA\, Vetere G Threat-dependent scaling of prelimbic dynamics to enhance fear representation Neuron. 2024 May. \n2. Vetere G\, Xia F\, Ramsaran A\, Tran L\, Josselyn S\, Frankland P. An inhibitory hippocampal–thalamic pathway modulates remote memory retrieval. Nature Neuroscience. 2021 May. \n3. Vetere G\, Tran L\, Moberg S\, Steadman P\, Restivo L\, Morrison F\, Ressler K\, Josselyn S\, Frankland P. Memory formation in the absence of experience. Nature Neuroscience. 2019 Jun. \n4. Vetere G\, Kenney JW\, Tran LM\, Xia F\, Steadman PE\, Parkinson J\, Josselyn SA\, Frankland PW. Chemogenetic interrogation of a brainwide fear memory network in mice. Neuron. 2017 Apr. \n5. Vetere G\, Restivo L\, Ross PJ\, Ammassari-Teule M\, Josselyn SA & Frankland PW. Spine growth in the anterior cingulate cortex is necessary for the consolidation of contextual fear memory PNAS\, 2011 May. \n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-gisella-vetere/
CATEGORIES:For scientists,home-event,Impromptu seminar
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DTSTART;TZID=Europe/Paris:20240619T140000
DTEND;TZID=Europe/Paris:20240619T140000
DTSTAMP:20260311T220925
CREATED:20240430T170215Z
LAST-MODIFIED:20240430T170928Z
UID:171256-1718805600-1718805600@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Maxime Cazorla
DESCRIPTION:Venue: Centre Broca \n\nMaxime Cazorla\nInstitut de Neuroscience de la Timone / INT Neurotechnology Center\nAix Marseille Université\nteam / ntc / twitter \nInvited by Clémentine Bosch Bouju (NutriNeuro) \nTitle\nStudying axon plasticity : from intracellular dynamics to large-scale rewiring \nAbstract\nLong regarded as a rigid and aging organ\, the adult brain is capable of profound reorganization at the macroscopic level of its cerebral circuits. This emerging concept\, known as ‘brain rewiring’\, postulates that neural circuits keep restructuring in response to neuronal activity. But what makes axonal rewiring efficient in the adult brain? How is it regulated with experience and learning? Alterations in brain connectivity exist in neurodegenerative diseases\, such as Huntington’s disease and Amyotrophic Lateral Sclerosis. Could we reverse engineer the rewiring capacity of the brain to restore dysfunctional networks on-demand? In the lab\, we address these burning questions by investigating the molecular and cellular underpinnings of axonal remodeling\, using an organ-on-a-chip approach\, in health and disease. \nIn this talk\, I will present how brain-on-chip microdevices helped us to discover unexpected intracellular mechanisms regulating axonal remodeling. I will also introduce our latest human-based models and technological development to improve biomedical research. Finally\, I will briefly talk about RAIL\, a photoinducible technology targeting axon remodeling programs to connect and disconnect neural networks on-demand. \nKey publications\nCazorla M\, de Carvalho FD\, Chohan MO\, Shegda M\, Chuhma N\, Rayport S\, Ahmari SE\, Moore H and Kellendonk C. (2014) Dopamine D2 receptors regulate the anatomical and functional balance of basal ganglia circuitry. Neuron. 2014 Jan 8;81(1):153-64. \nVirlogeux A\, Moutaux E\, Christaller W\, Genoux A\, Bruyère J\, Fino E\, Charlot B\, Cazorla M and Saudou F. (2018) Reconstituting Corticostriatal Network on‐a‐Chip Reveals the Contribution of the Presynaptic Compartment to Huntington’s Disease. Cell Reports. 2018 Jan 2;22(1):110‐122 \nMoutaux E\, Christaller W\, Scaramuzzino C\, Genoux A\, Charlot B\, Cazorla M* and Saudou F*. (2018) Neuronal network maturation differently affects secretory vesicles and mitochondria transport in axons. Scientific Reports. 2018 Sep 7;8(1):13429. \nMoutaux E\, Charlot B\, Genoux A\, Saudou F and Cazorla M. (2018) An integrated microfluidic/microelectrode array for the study of activity‐dependent intracellular dynamics in neuronal networks. Lab Chip. 2018 Nov 6;18(22):3425‐3435 \nPoinsot M\, Maurin J\, Cesar W and Cazorla M. (2023) Liquid distribution system for a fluidic chip. Eur. Patent.EP/2023/03848 \n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-maxime-cazorla/
CATEGORIES:For scientists,home-event,Impromptu seminar
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