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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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TZID:Europe/Paris
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DTSTART;TZID=Europe/Paris:20251205T090000
DTEND;TZID=Europe/Paris:20251205T120000
DTSTAMP:20260419T204712
CREATED:20251002T135514Z
LAST-MODIFIED:20251202T151046Z
UID:188433-1764925200-1764936000@www.bordeaux-neurocampus.fr
SUMMARY:Mini symposium - "Sensori-motor integration in health and disease"
DESCRIPTION:Venue : amphithéâtre BBS \nIn the frame of Louison Brochoire thesis defense and of the DECODE Pain international associated laboratory. \n\nSpeakers\nChair: Yves de Koninck and Pascal Fossat \n09:15-09:45 : Martin Levesque – Université Laval\, Canada\nCell and Gene Therapy Approaches for Repairing Motor Dysfunction in Parkinson’s Disease \n09:50-10:20 : Christian Ethier – Université Laval\, Canada\nModulation of motor cortical excitability and plasticity by dopaminergic centers \nCoffee break \n10:40-11:10 : Matilde Cordero-Erausquin – Institut des Neurosciences Cellulaires et Intégratives\, université de Stasbourg\, France\nUnraveling corticospinal contributions to locomotion \n11:20-11:50 : Francesco Ferrini – Dipartimento di Scienze Veterinarie – DSV\, Turin\, Italie\nSex differences in spinal inhibitory circuits for nociceptive gating \n  \n  \n
URL:https://www.bordeaux-neurocampus.fr/en/event/mini-symposium-sensori-motor-integration-in-health-and-disease/
CATEGORIES:For scientists,home-event,IMN,Symposium
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251205T113000
DTEND;TZID=Europe/Paris:20251205T113000
DTSTAMP:20260419T204712
CREATED:20250624T073456Z
LAST-MODIFIED:20251201T115626Z
UID:185503-1764934200-1764934200@www.bordeaux-neurocampus.fr
SUMMARY:CANCELLED // PhD Seminar - Wolf-Julian Neumann
DESCRIPTION:Venue: Centre Broca \nThis seminar will be rescheduled next year.\n\nProf. Wolf-Julian Neumann\nAssistant Professor for Interventional and Cognitive Neuromodulation\nCharité – Universitätsmedizin Berlin\nMovement Disorders and Neuromodulation Section\nCharite\, Berlin\, Germany\nhttps://www.wjneumann.org/ \nInvited by Yasmin Guerra (IMN) \n  \n
URL:https://www.bordeaux-neurocampus.fr/en/event/phd-seminar-wolf-julian-neumann/
CATEGORIES:For scientists,IMN,Monthly conferences
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251205T140000
DTEND;TZID=Europe/Paris:20251205T140000
DTSTAMP:20260419T204712
CREATED:20250617T081810Z
LAST-MODIFIED:20251128T134210Z
UID:184951-1764943200-1764943200@www.bordeaux-neurocampus.fr
SUMMARY:Thesis defense - Louison Brochoire
DESCRIPTION:Venue : Centre Broca \nZoom: https://u-bordeaux-fr.zoom.us/j/88929744526?pwd=DMmc7vED2aHOhbu7PBdQ78C0yjmD5p.1\, ID de réunion: 889 2974 4526 \n\nLouison Brochoire \nTeam : Monoamines\, Parkinson and Pain\nIMN \nThesis directed by Pascal Fossat and Yves de Koninck \n\nTitle\nDevelopment and implementation of innovative techniques for the functional study of dorsal horn neurones in the mouse spinal cord \nAbstract\nMy thesis focused on the study of somatosensation and pain. Despite the critical role of the dorsal horn of the spinal cord as the primary site for processing and relaying somatosensory information\, the underlying neuronal circuits and mechanisms remain poorly understood. Recent studies have identified a population of neurons expressing the Tachykinin 1 (Tac1) gene\, which are essential for coping behaviors induced by intense noxious stimuli. However\, the nature and functional properties of these neurons are still not fully described. In the first part of my PhD\, I performed a thorough characterization of Tac1 neurons using slice electrophysiology and in vivo imaging techniques in both naïve and neuropathic conditions following sciatic nerve injury. These results revealed a neuronal population predominantly composed of polymodal nociceptors under physiological conditions\, whose properties are altered following sciatic nerve injury. On the other hand\, most studies investigating spinal cord electrophysiological properties have relied on in vitro preparations or anesthetized animals. However\, neuronal activity and properties can differ substantially under these conditions compared to the awake state. Studying neuronal activity in awake\, freely moving animals has been limited by the technical challenges related to spinal cord inaccessibility. In the second part of my project\, we developed and introduced a novel electrode system to record from the dorsal horn of the spinal cord in freely moving mice. Using this approach\, we demonstrated that spontaneous spinal activity varies according to the animal’s state of arousal and that the encoding of sensory information depends on the integrated modalities. Taken together\, our results provide new insights into the role of the dorsal horn in processing somatosensory information in both naïve and neuropathic conditions. \nKey words\nSpinal cord\, Tachykinin 1\, Somatosensation\, Pain\, Freely moving \nJury\nDr.Matilde Cordero-Erausquin\, INCI\, Université de Strasbourg \nDr. Ipek Yalcin\, INCI\, Université de Strasbourg\nDr. Francesco Ferrini\, Université de Turin\nDr. Christian Ethier\, CERVO\, Université Laval\nDr. Yves De Koninck\, CERVO\, Université Laval\nDr. Pascal Fossat\, IMN\, Université de Bordeaux\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/thesis-defense-louison-brochoire/
CATEGORIES:IMN,Thesis
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251205T150000
DTEND;TZID=Europe/Paris:20251205T150000
DTSTAMP:20260419T204712
CREATED:20251029T103517Z
LAST-MODIFIED:20251121T135612Z
UID:189108-1764946800-1764946800@www.bordeaux-neurocampus.fr
SUMMARY:Thesis defense - Elise Cosenza
DESCRIPTION:Venue: BBS\nOn zoom : https://u-bordeaux-fr.zoom.us/j/89385176470?pwd=QsjYpcSk1PYVbZySSgkSUTXbqrpUGM.1 \n \nThesis defended in french \n\nElise Cosenza \nTeam: Neurofunctional imaging group (GIN)\nIMN \nThesis directed by Laurent Petit \nTitle\nDevelopment of diffusion MRI and tractography of brain white matter fibers in the small animal at 7 Tesla \nAbstract\nThe study of brain connectivity in mice is a major challenge for preclinical research. Although the mouse brain is anatomically simpler than the human brain\, it remains a complex system. Its anatomical organisation is now well described and segmented thanks to the many atlases available\, but the connections between the different structures are still poorly understood. White matter\, formed by bundles of axons connecting brain regions\, constitutes a network whose characterisation is essential to better understand the overall functioning of the murine brain. \nDiffusion magnetic resonance imaging (dMRI) has established itself as an essential method for non-invasive brain studies. It is based on measuring the movement of water molecules and allows indirect deduction of tissue architecture and brain connectivity\, given that the brain is composed of more than 80% water. Using this data\, tractography can be used to highlight all the brain’s connections. Although widely developed in humans and enhanced by numerous processing tools\, dMRI and tractography have several limitations due to their indirect nature. To validate and refine the results\, fMRI and tractography must be combined with complementary\, sometimes invasive methods that provide essential “ground truth” data. \nMethodologically\, diffusion MRI protocols were optimised on ex vivo mouse brains\, enabling reliable\, quantitative diffusion metrics to be obtained across all brain regions. An automated tool for processing dMRI data\, incorporating quality controls and artefact corrections\, was developed to generate these metrics and reconstruct a complete tractogram of white matter connectivity. Finally\, the validity of these results was confirmed by directly comparing the tractograms with histological data\, using tools dedicated to coupling MRI and histology. \nThis work paves the way for better characterisation of brain connectivity networks in preclinical animal models. These advances offer major prospects for understanding how the brain works and its plasticity\, as well as for studying mouse models of neurological disorders. \nKey words\nMRI; Tratography; Brain; White Matter; Mice; Diffusion \nPublication\n\n“MRI R2* captures inflammation in disconnected brain structures after stroke: a translational study”\nAn optimised mutli-shot EPI protocol for ex vivo mouse brain diffusion MRI with Gd-DOTA contrast enhancement (submitted)\n\nJury\n\nDr. Emmanuel Caruyer\, CR\, IRISA – Rennes\, Rapporteur\nPr. Ileana Jelescu\, Assistant professor\, Lausanne University Hospital et University of Lausanne – Lausanne (Suisse)\, Rapporteure\nDr. Angèle Viola\, DR\, Centre de Résonance Magnétique Biologique et Médicale – Marseille\, Examinatrice\nPr. Maxime Descoteaux\, Professeur titulaire\, Sherbrooke Connectivity Imaging Laboratory – Sherbrooke (Canada)\, Invité\nDr. Sylvain Miraux\, DR\, Centre de Résonance Magnétique des Systèmes Biologiques – Bordeaux\, Invité\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/soutenance-de-these-elise-cosenza/
CATEGORIES:IMN,Thesis
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