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X-WR-CALNAME:Bordeaux Neurocampus
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X-WR-CALDESC:Events for Bordeaux Neurocampus
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DTSTART;TZID=Europe/Paris:20220408T080000
DTEND;TZID=Europe/Paris:20220408T170000
DTSTAMP:20260521T063459
CREATED:20220408T082713Z
LAST-MODIFIED:20240405T115925Z
UID:147130-1649404800-1649437200@www.bordeaux-neurocampus.fr
SUMMARY:Soutenance d'HDR - Lisa Roux
DESCRIPTION:Lisa Roux\nIINS \nEn anglais \nTitle\nNeurophysiological substrates of memory formation: insights from olfactory and hippocampal networks \nBiosketch\nLisa Roux is a researcher at CNRS leading the team “Olfaction and Memory” at the Interdisciplinary Institute for Neuroscience (IINS\, CNRS UMR5297\, Bordeaux University\, France) since 2018. She did her PhD in the lab of Christian Giaume at the Collège de France where she worked on neuro-glial interactions in the olfactory system using primarily slice electrophysiology methods. Her work unraveled a bi-directional loop of interactions between neuron and astrocyte networks which could impact olfactory information processing. In 2012\, Lisa Roux joined the lab of Gyorgy Buzsáki at the New York University (USA) as a postdoctoral fellow. There\, she used advanced in vivo electrophysiology and optogenetic approaches in freely moving mice to understand the mechanisms of hippocampal oscillations and their function in spatial memory processes. Notably\, she studied the cellular mechanisms involved in two types of network oscillations\, fundamental to memory function in the hippocampus: theta and sharp wave ripple oscillations. Her work also uncovered a key role played by sharp wave ripple oscillations in the maintenance of the hippocampal “cognitive map” during spatial learning. The role played by inhibitory interneurons in shaping circuit functions in the behaving animal was at the core of her work. As an independent group leader at the IINS\, she broadened her field of investigation by studying the neuronal substrates of olfactory memory formation. \nSelected publications\nRoux L.\, Hu B.\, Eichler R.\, Stark E.\, Buzsáki G. Sharp wave ripples during learning stabilize the hippocampal spatial map. Nature Neuroscience\, 20(6):845-853 (2017) \nRoux L.\, Madar A.\, Lacroix MM\, Chenju Y.\, Benchenane K.\, Giaume C. Astroglial Connexin 43 Hemichannels Modulate Olfactory Bulb Slow Oscillations. J Neurosci.\, 35(46):15339-52 (2015) \nStark E.*\, Roux L.*\, Eichler R.*\, Senzai Y.\, Royer S.\, Buzsáki G. (*equal contribution) Pyramidal cell-interneuron interactions underlie hippocampal ripple oscillations. Neuron\, 83(2):467-80 (2014) \nStark E.\, Eichler R.\, Roux L.\, Fujisawa S.\, Rotstein HG\, Buzsáki G. Inhibition-induced theta resonance in cortical circuits. Neuron\, 80(5):1263-76 (2013) \nRoux L.\, Benchenane K.\, Rothstein J.\, Bovento G.\, Giaume C. Plasticity of astroglial networks in the olfactory glomeruli. Proc Natl Acad Sci U S A.\, 108(45):18442-6 (2011) \nJury\nGuillaume Ferreira (DR INRAE\, HDR\, University of Bordeaux): President\nEmmanuelle Courtiol (CR CNRS\, HDR\, University of Lyon) : Rapporteur\nStéphanie Trouche (CR INSERM\, HDR\, University of Montpellier) : Rapporteur\nKarim Benchenane (DR CNRS\, HDR\, Sorbonne University) : Rapporteur\nGabrielle Girardeau (CR INSERM\, HDR\, Sorbonne University) : Examiner\nGiovanni Marsicano (DR INSERM\, HDR\, University of Bordeaux) : Examiner \n
URL:https://www.bordeaux-neurocampus.fr/en/event/soutenance-dhdr-lisa-roux/
CATEGORIES:HDR,home-event
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DTSTART;TZID=Europe/Paris:20220408T113000
DTEND;TZID=Europe/Paris:20220408T123000
DTSTAMP:20260521T063459
CREATED:20220111T083247Z
LAST-MODIFIED:20220404T094023Z
UID:144974-1649417400-1649421000@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Timothée Levi
DESCRIPTION:Venue : Centre Broca Nouvelle-Aquitaine \n\nTimothée Levi\n\nIMS\nUniversité de Bordeaux\nwww.ims-bordeaux.frInvited by Olivier Thoumine (IINS)\nTitle\nBiomimetic Spiking Neural Network and real-time closed-loop bio-hybrid systems \nAbstract\nMillions of people worldwide are affected by neurological disorders which disrupt connections between brain and body causing paralysis or affect cognitive capabilities. Such a number is likely to increase in the next years and current assistive technology is still limited. Since last decades Brain-Machine Interfaces (BMIs) and generally neuroprosthesis have been object of extensive research and may represent a valid treatment for such disabilities. The realization of such prostheses implies that we know how to interact with neuronal cell assemblies\, taking into account the intrinsic spontaneous activity of neuronal networks and understanding how to drive them into a desired state or to produce a specific behavior. The long-term goal of replacing damaged brain areas with artificial devices also requires the development of Spiking Neural Network (SNN) system. They will fit with the recorded electrophysiological patterns and will produce in their turn the correct stimulation patterns for the brain so as to recover the desired function. \nI will first describe the implementation of biologically realistic neural network models\, spanning from the electrophysiological properties of one single neuron up to network plasticity rules. This digital implementation computes in real-time biologically realistic cortical neurons and motor neurons\, synapses and synaptic plasticity. It is freely configurable from an independent-neuron configuration to different neural network configurations. This SNN has been used for the development of a neuromorphic chip for neuroprosthesis\, which has to replace or mimic the functionality of a damaged part of the central nervous system. \nI will then describe bio-hybrid system and show some bio-hybrid experiments using SNN for real-time bidirectional communication with living neurons. \n  \nReference for SNN description: \nhttps://www.frontiersin.org/articles/10.3389/fnins.2019.00377/full \nReferences for bio-hybrid system: \nhttps://www.sciencedirect.com/science/article/pii/S2589004219302731 \nhttps://www.sciencedirect.com/science/article/pii/S2589004220307811 \nhttps://www.nature.com/articles/s41598-020-63934-4 \n  \n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminaire-timothee-levi/
CATEGORIES:For scientists,home-event,Seminars
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