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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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TZID:Europe/Paris
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TZOFFSETFROM:+0100
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DTSTART:20190331T010000
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DTSTART:20191027T010000
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DTSTART;TZID=Europe/Paris:20190625T090000
DTEND;TZID=Europe/Paris:20190709T120000
DTSTAMP:20260516T072945
CREATED:20190207T162346Z
LAST-MODIFIED:20191030T154757Z
UID:103112-1561453200-1562673600@www.bordeaux-neurocampus.fr
SUMMARY:Cajal course : Biosensors and actuators for cellular and systems neuroscience
DESCRIPTION:Lectures\nFree entrance / Venue : CGFB. \nTuesday 25th June – 9:00\nHaruhiko Bito – Tokyo University\, Japan \nTuesday 25th June – 11:00\nScott Sternson – Janelia Research Campus\, HHMI\, USA \nThursday 27th June – 9:00\nOliver Griesbeck – MPI for Neurobiology \, Germany \nThursday 27th June – 11:00\nRyohei Yasuda – Max Planck Florida Institute \, USA \nSaturday 29th June – 9:00\nMark J. Schnitzer – Stanford University\, USA \nSaturday 29th June – 11:00\nKarl Deisseroth – Stanford University \, USA \nMonday 1st July – 9:00\nMichael LIN – Stanford University USA \nMonday 1st July – 11:00\nPeter Hegemann – Humboldt University \, Germany \nFriday 5th July – 9:00\nThomas Oertner – Hamburg Eppendorf University\, Germany \nFriday 5th July – 11:00\nValentina Emiliani – Paris Descartes University\, France \nMonday 8th July – 9:00\nThomas Kash – University of North Carolina \, USA \nMonday 8th July – 11:00\nStéphane Dieudonné – IBENS\, France \nTuesday 9th July – 9:00\nOfer Yizhar – Weizmann Institute of Science – Israel \nTuesday 9th July – 11:45\nSandrine POUVREAU – IINS\, University of Bordeaux\, France \n  \nAbout the course\nOptical techniques have become indispensable for biological research in recent decades. Systems neuroscience has seen some of the most exciting developments in this regard\, following the development of genetically-encoded biosensors and actuators that allow multi-modal interrogation of neural circuit function. This course will provide participants with an in-depth understanding of the principles behind the design and application of these tools\, and enable hands-on experience with optogenetic and chemogenetic actuators and with genetically encoded reporters of calcium\, voltage and metabolism. Experimental work will span a wide range of systems and experimental preparations\, utilizing standard microscopy methods as well as advanced hardware for parallel excitation and imaging of neuronal circuits. In addition to the practical aspects of utilizing these powerful tools\, the course will cover the conceptual issues of data analysis and interpretation. \nCourse director \nOfer Yizhar\nWeizmann Institute of Science\nIsrael \n  \n  \nCo-directors \nMichael Lin\nStanford University\nUSA\n \n  \n  \n \nSandrine Pouvreau\nIINS\nUniversity of Bordeaux\nFrance \n  \n  \n  \nThis course is organised in partnership with the Bordeaux Imaging Center (BIC).\n \n  \n  \n\nKeynote Speakers\nHaruhiko Bito – Tokyo University\, Japan\nKarl Deisseroth – Stanford University \, USA\nStéphane Dieudonné – Inserm – Institut de Biologie de l’École Normale Supérieure (IBENS)\, France\nValentina Emiliani – Paris Descartes University\, France\nOliver Griesbeck – MPI for Neurobiology \, Germany\nPeter Hegemann – Humboldt University \, Germany\nThomas Kash – University of North Carolina \, USA\nThomas Oertner – Hamburg Eppendorf University\, Germany\nMark J. Schnitzer – Stanford University\, USA\nScott Sternson – Janelia Research Campus\, HHMI\, USA\nRyohei Yasuda – Max Planck Florida Institute \, USA \n
URL:https://www.bordeaux-neurocampus.fr/en/event/cajal-course-biosensors-and-actuators-for-cellular-and-systems-neuroscience/
CATEGORIES:Cajal Lectures,For scientists,home-event
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20190705T110000
DTEND;TZID=Europe/Paris:20190705T120000
DTSTAMP:20260516T072945
CREATED:20190205T133134Z
LAST-MODIFIED:20191030T154756Z
UID:102969-1562324400-1562328000@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Stephanie Borgland
DESCRIPTION:Venue : Centre Broca Nouvelle-Aquitaine \n\nDr. Stephanie Borgland\nAssociate Professor\,\nThe Hochkiss Brain Institute\,\nCalgary\, Canada \nInvited by Guillaume Ferreira\nNutrineuro \n\nAbstract\nThe orbitofrontal cortex (OFC) receives sensory information about food and integrates these signals with expected outcomes. Thus\, the OFC registers the current value of foods and updates actions based on this information. OFC lesions in animals show a lack of food devaluation. Interestingly\, obese humans and rats fed a cafeteria diet have impaired devaluation of food rewards\, implicating a potential obesity-induced dysfunction the OFC. We will present findings demonstrating that long-term exposure to a palatable diet alters astrocyte modulation of glutamate homeostasis within the OFC\, resulting in enhanced endocannabinoid signalling and tone via Group 1 mGluR activation\, which then leads to decreased GABAergic synaptic transmission. We will also present data showing impaired reward devaluation in obese rodents and that this can be restored by increasing GABAergic tone in the OFC.  Together these results suggest that obesogenic diets disrupt synaptic transmission in the OFC\, which may influence cognitive and emotional processing of decision-making in obesity. \nRecent publications\nNaef L\, Seabrook L\, Hsiao J\, Li C\, Borgland SL (2019).  Insulin in the ventral tegmental area reduces cocaine-evoked dopamine in the nucleus accumbens in vivo. Eur J Neurosci. in press \nBalsevich G\, Sticht M\, Bowles NP\, Singh A\, Lee TTY\, Li Z\, Chelikani PK\, Lee FS\, Borgland SL\, Hillard CJ\, McEwen BS\, Hill MN (2018). Role for fatty acid amide hydrolase (FAAH) in the leptin-mediated effects on feeding and energy balance. Proc Natl Acad Sci U S A. 115(29):7605-7610. \nMills F\, Globa AK\, Liu S\, Cowan CM\, Mobasser M\, Phillips AG\, Borgland SL\, Bamji SX (2017). Cadherins mediate cocaine-induced synaptic plasticity and behavioral conditioning. Nat Neurosci. 20(4):540-549. \nBaimel C\, Lau BK\, Qiao M\, Borgland SL (2017).  Projection-Target-Defined Effects of Orexin and Dynorphin on VTA Dopamine Neurons. Cell Rep. 18(6):1346-1355. \nThompson JL\, Drysdale M\, Baimel C\, Kaur M\, MacGowan T\, Pitman KA\, Borgland SL (2017). Obesity-Induced Structural and Neuronal Plasticity in the Lateral Orbitofrontal Cortex. Neuropsychopharmacology 42(7):1480-1490. \nLiu S\, Globa AK\, Mills F\, Naef L\, Qiao M\, Bamji SX\, Borgland SL (2016). Consumption of palatable food primes food approach behavior by rapidly increasing synaptic density in the VTA. Proc Natl Acad Sci U S A. 113(9):2520-5. \nThompson JL\, Yang J\, Lau B\, Liu S\, Baimel C\, Kerr LE\, Liu F\, Borgland SL (2016). Age-Dependent D1-D2 Receptor Coactivation in the Lateral Orbitofrontal Cortex Potentiates NMDA Receptors and Facilitates Cognitive Flexibility. Cereb Cortex. 26(12):4524-4539. \nBaimel C\, Borgland SL (2015).  Orexin Signaling in the VTA Gates Morphine-Induced Synaptic Plasticity. J Neurosci. 35(18):7295-303 \n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-stephanie-borgland/
CATEGORIES:home-event,Seminars
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