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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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DTSTART:20190331T010000
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DTSTART:20191027T010000
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DTSTART;VALUE=DATE:20190521
DTEND;VALUE=DATE:20190608
DTSTAMP:20260516T084908
CREATED:20190207T163708Z
LAST-MODIFIED:20191030T154801Z
UID:103124-1558396800-1559951999@www.bordeaux-neurocampus.fr
SUMMARY:CAJAL course : Brain Homeostasis and Neurovascular Coupling
DESCRIPTION:Talks (venue: CGFB)\nTuesday 21st May \n9:00 Martin LAURITZEN\n« Basics of brain homeostasis and cerebral blood flow regulation » \nWednesday 22nd May \n9:00 Edith HAMEL\n« The cellular basis of the neurovascular unit\, regulation and pathology » \nThursday 23th May \n9:00 Ulrich DIRNAGL\n« Increasing the validity and reproducibility of neurovascular research » \nSaturday 25th May \n9:00 David ATTWELL\n« Control of cerebral blood flow by capillary pericytes in health\, ischaemia and Alzheimer’s disease » \nMonday 27th May \n9:00 Constantino IADECOLA\n« Neurovascular bases of cognitive dysfunction: blood flow and beyond » \nThursday 30th May \n9:00 Mickaël TANTER\n« Functional and superresolution ultrasound for whole brain neuroimaging » \nFriday 31st May \n9:00 Robert G. THORNE \n11:00 Bruno WEBER\n« Metabolic coupling of brain cells » \nSaturday 1st June \n9:00 Jean-François GHERSI-EGEA\n« Known and less known functions of the choroid plexus-CSF system » \nMonday 3rd June \n9:00 Britta ENGELHARDT\n« The brain barriers establish CNS immune privilege » \nThursday 6th June \n9:00 Anna DEVOR\n« Neurovascular coupling and O2 metabolism » \n11:00 Jérôme BADAUT\n« Water homeostasis and brain edema » \nFriday 7th June \n9:00 Frédéric LESAGE\n« Changes in microvasculature properties with age and its impact on MRI modelling » \nAbout the course\nThe Neurovascular unit (NVU) is a physiological entity that consists of fine-tuned interactions between cerebral blood vessels\, pericytes\, astrocytes\, immune cells and neurons in order to maintain brain homeostasis. The NVU contributes to brain vessel properties such as blood-brain barrier (BBB) and cerebral blood flow regulation. Several brain disorders are associated with NVU dysfunction. There have been several recent advances in knowledge and in the technologies available to study the NVU. This advanced course will allow students to gain basic knowledge and hands-on experience with various techniques\, such as in vivo/ex vivo high-resolution imaging\, magnetic resonance imaging\, brain vascular pathology rodent models and in vitro BBB models. \nCourse director \n\n\n\n\n\n\n\nMartin Lauritzen\nDepartment of Neuroscience\nUniversity of Copenhagen\nand Rigshospitalet\nDenmark\n\n\n\n\nCo-directors \n\n\n\n\n\n\n\n\n\n\n\n Edith Hamel\nMontréal Neurological Institute\nMcGill University\nCanada\n\nJérôme Badaut\nBrain Molecular Imaging Lab\nCNRS – INCIA\nUniversity of Bordeaux\nFrance\n \n\n\n\n  \nKeynote speakers \nDavid Attwell (Department of Neuroscience\, Physiology & Pharmacology\, University College London\, UK)\nAnna Devor (Department of Neurosciences\, UC San Diego School of Medicine\, USA)\nUlrich Dirnagl (Department of Experimental Neurology\, Charité Universitätsmedizin Berlin\, Germany)\nBritta Engelhardt (Theodor Kocher Institute\, University of Bern\, Switzerland)\nJean-François Ghersi-Egea (Fluids and barriers of the CNS\, Lyon Neuroscience Research Center\, France)\nCostantino Iadecola (Feil Family Brain & Mind Research Institute\, Weill Cornell Medicine\, New York\, USA)\nFrédéric Lesage (Department of Electrical Engineering\, Polytechnique Montréal\, Canada)\nMickael Tanter (French National Institute for Health and Medical Research\, Institut Langevin\, ESPCI\, Paris\, France)\nRobert G. Thorne (Denali Therapeutics\, South San Francisco\, California\, USA/ Pharmaceutical Sciences Division\, University of Wisconsin-Madison\, USA)\nBruno Weber (Institute of Pharmacology and Toxicology\, University of Zurich\, Switzerland) \n
URL:https://www.bordeaux-neurocampus.fr/en/event/cajal-course-brain-homeostasis-and-neurovascular-coupling/
CATEGORIES:Cajal Lectures,home-event
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DTSTART;TZID=Europe/Paris:20190607T113000
DTEND;TZID=Europe/Paris:20190607T123000
DTSTAMP:20260516T084908
CREATED:20190125T153240Z
LAST-MODIFIED:20190522T153643Z
UID:102567-1559907000-1559910600@www.bordeaux-neurocampus.fr
SUMMARY:Monthly PhD seminar - Matthew Hill
DESCRIPTION:Venue: Centre Broca Nouvelle-Aquitaine / Salle de Conférence \n\nMatthew Hill\nHotchkiss Brain Institute\,\nMathison Centre for Mental Health Research.\nDepartments of Cell Biology and Anatomy and Psychiatry. \nInvited by the NBA and Bordeaux Neurocampus.\n \n\nAbstract\nEndocannabinoids are well established to buffer stress responses in the brain\, with emerging evidence suggest that they exhibit both tonic control of stress responses at rest\, as well as phasic control in response to stress itself. Converging evidence has indicated that anandamide may be the primary endocannabinoid regulating tonic control of the stress response\, and that disruption of anandamide signaling may facilitate generation of a stress response. Our work has suggested that this effect may particularly mediated by local actions within the amygdala. Translational work in human populations\, using both genetics and pharmacology as a window into the effects of anandamide signaling in humans\, has suggested that similar to rodents\, anandamide may constrain stress\, anxiety and fear\, in part through regulating amygdala reactivity to threat and challenge. Together\, these data would suggest that approaches to regulating anandamide signaling in humans may be a novel approach to treating stress-related psychiatric illnesses. \nSelected publications\nProtective effects of elevated anandamide on stress and fear-related behaviors: translational evidence from humans and mice.\nMol Psychiatry. 2018 Aug 17. doi: 10.1038/s41380-018-0215-1. \nIntegrating Endocannabinoid Signaling and Cannabinoids into the Biology and Treatment of Posttraumatic Stress Disorder\nNeuropsychopharmacology. 2018 Jan;43(1):80-102. doi: 10.1038/npp.2017.162. \nCorticotropin-releasing hormone drives anandamide hydrolysis in the amygdala to promote anxiety. \nJ Neurosci. 2015 Mar 4;35(9):3879-92. doi: 10.1523/JNEUROSCI \nFAAH genetic variation enhances fronto-amygdala function in mouse and human.\nNat Commun. 2015 Mar 3;6:6395. doi: 10.1038/ncomms7395. \n
URL:https://www.bordeaux-neurocampus.fr/en/event/monthly-phd-seminar-matthew-hill/
CATEGORIES:For scientists,home-event,Monthly conferences
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