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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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DTSTART:20190331T010000
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DTSTART:20191027T010000
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DTSTART;VALUE=DATE:20190521
DTEND;VALUE=DATE:20190608
DTSTAMP:20260516T101938
CREATED:20190207T163708Z
LAST-MODIFIED:20191030T154801Z
UID:103124-1558396800-1559951999@www.bordeaux-neurocampus.fr
SUMMARY:CAJAL course : Brain Homeostasis and Neurovascular Coupling
DESCRIPTION:Talks (venue: CGFB)\nTuesday 21st May \n9:00 Martin LAURITZEN\n« Basics of brain homeostasis and cerebral blood flow regulation » \nWednesday 22nd May \n9:00 Edith HAMEL\n« The cellular basis of the neurovascular unit\, regulation and pathology » \nThursday 23th May \n9:00 Ulrich DIRNAGL\n« Increasing the validity and reproducibility of neurovascular research » \nSaturday 25th May \n9:00 David ATTWELL\n« Control of cerebral blood flow by capillary pericytes in health\, ischaemia and Alzheimer’s disease » \nMonday 27th May \n9:00 Constantino IADECOLA\n« Neurovascular bases of cognitive dysfunction: blood flow and beyond » \nThursday 30th May \n9:00 Mickaël TANTER\n« Functional and superresolution ultrasound for whole brain neuroimaging » \nFriday 31st May \n9:00 Robert G. THORNE \n11:00 Bruno WEBER\n« Metabolic coupling of brain cells » \nSaturday 1st June \n9:00 Jean-François GHERSI-EGEA\n« Known and less known functions of the choroid plexus-CSF system » \nMonday 3rd June \n9:00 Britta ENGELHARDT\n« The brain barriers establish CNS immune privilege » \nThursday 6th June \n9:00 Anna DEVOR\n« Neurovascular coupling and O2 metabolism » \n11:00 Jérôme BADAUT\n« Water homeostasis and brain edema » \nFriday 7th June \n9:00 Frédéric LESAGE\n« Changes in microvasculature properties with age and its impact on MRI modelling » \nAbout the course\nThe Neurovascular unit (NVU) is a physiological entity that consists of fine-tuned interactions between cerebral blood vessels\, pericytes\, astrocytes\, immune cells and neurons in order to maintain brain homeostasis. The NVU contributes to brain vessel properties such as blood-brain barrier (BBB) and cerebral blood flow regulation. Several brain disorders are associated with NVU dysfunction. There have been several recent advances in knowledge and in the technologies available to study the NVU. This advanced course will allow students to gain basic knowledge and hands-on experience with various techniques\, such as in vivo/ex vivo high-resolution imaging\, magnetic resonance imaging\, brain vascular pathology rodent models and in vitro BBB models. \nCourse director \n\n\n\n\n\n\n\nMartin Lauritzen\nDepartment of Neuroscience\nUniversity of Copenhagen\nand Rigshospitalet\nDenmark\n\n\n\n\nCo-directors \n\n\n\n\n\n\n\n\n\n\n\n Edith Hamel\nMontréal Neurological Institute\nMcGill University\nCanada\n\nJérôme Badaut\nBrain Molecular Imaging Lab\nCNRS – INCIA\nUniversity of Bordeaux\nFrance\n \n\n\n\n  \nKeynote speakers \nDavid Attwell (Department of Neuroscience\, Physiology & Pharmacology\, University College London\, UK)\nAnna Devor (Department of Neurosciences\, UC San Diego School of Medicine\, USA)\nUlrich Dirnagl (Department of Experimental Neurology\, Charité Universitätsmedizin Berlin\, Germany)\nBritta Engelhardt (Theodor Kocher Institute\, University of Bern\, Switzerland)\nJean-François Ghersi-Egea (Fluids and barriers of the CNS\, Lyon Neuroscience Research Center\, France)\nCostantino Iadecola (Feil Family Brain & Mind Research Institute\, Weill Cornell Medicine\, New York\, USA)\nFrédéric Lesage (Department of Electrical Engineering\, Polytechnique Montréal\, Canada)\nMickael Tanter (French National Institute for Health and Medical Research\, Institut Langevin\, ESPCI\, Paris\, France)\nRobert G. Thorne (Denali Therapeutics\, South San Francisco\, California\, USA/ Pharmaceutical Sciences Division\, University of Wisconsin-Madison\, USA)\nBruno Weber (Institute of Pharmacology and Toxicology\, University of Zurich\, Switzerland) \n
URL:https://www.bordeaux-neurocampus.fr/en/event/cajal-course-brain-homeostasis-and-neurovascular-coupling/
CATEGORIES:Cajal Lectures,home-event
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DTSTART;TZID=Europe/Paris:20190524T113000
DTEND;TZID=Europe/Paris:20190524T123000
DTSTAMP:20260516T101938
CREATED:20190103T181228Z
LAST-MODIFIED:20191030T154800Z
UID:101902-1558697400-1558701000@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Philippe Séguéla
DESCRIPTION:\n	\n		\n			Venue: Centre Broca Nouvelle-Aquitaine / conference room \nPhilippe Séguéla\, PhD\nMontreal Neurological Institute\nThe Alan Edwards Centre for Research on Pain\nDept. Neurology & Neurosurgery – Faculty of Medicine\nMcGill University\nhttps://seguela-lab.org// \nInvited by: Eric Boué-Grabot\nPhD – Directeur de Recherche CNRS\nInstitut des Maladies Neurodégénératives \n\n		\n	\n\n	\n		\n			\nDr. Philippe Séguéla is Full Professor in the department of Neurology & Neurosurgery of McGill University in Montreal. Trained in France\, Canada and the US\, his research laboratory is located at the world-renowned Montreal Neurological Institute. His work primarily focuses on the physiology of sensory ion channels expressed in genetically-defined neurons at the source of somatosensation and pain perception. His team uses a multidisciplinary functional approach based on transgenic mouse models\, in vivo optogenetics\, chemogenetics\, calcium imaging\, electrophysiology and quantitative behavioural assays to investigate the molecular substrates of pain in peripheral and cortical pathways. This presentation will articulate around novel insights on the coding of somatosensory modalities by primary nociceptors gained from their selective activation in vivo in freely behaving animals. The long-term goal of Dr. Séguéla’s team and their collaborators is to contribute to the understanding of key pathological mechanisms underlying the somatosensory\, affective and cognitive deficits induced by chronic pain conditions\, in search for novel tractable drug targets and effective analgesic treatments without the side effects of opioids. \n\n\n		\n	\nRecent related publications\n\n	\n		\n			\nDaou I\, Tuttle AH\, Longo G\, Ase AR\, Wieskopf JS\, Bonin R\, De Koninck Y\, Wood JN\, Ribeiro-da-Silva A\, Mogil JS\, Séguéla P. (2013) Remote optogenetic activation and sensitization of pain pathways in freely moving mice. Journal of Neuroscience 33:18631-40.\nCordeiro Matos S\, Zhang Z\, Séguéla P (2015) Peripheral neuropathy induces HCN channel dysfunction in pyramidal neurons of the medial prefrontal cortex. Journal of Neuroscience 35: 13244-56.\nDaou I\, Beaudry H\, Ase AR\, Wieskopf J\, Ribeiro-da-Silva A\, Mogil JS\, Séguéla P (2016) Optogenetic silencing of Nav1.8 afferents alleviates inflammatory and neuropathic pain. eNeuro 3:0140-15.\nBeaudry H\, Daou I\, Ase AR\, Ribeiro da Silva A\, Séguéla P. (2017) Distinct behavioral responses evoked by selective optogenetic stimulation of the major TRPV1+ and MrgD+ subsets of C-fibers. Pain 158:2329-39.\nBernier LP\, Ase AR\, Séguéla P. (2018) P2X receptor-channels in chronic pain pathways. British Journal of Pharmacology 175:2219-30.\n\n  \n\n		\n	\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-philippe-seguela/
LOCATION:Centre Broca Nouvelle-Aquitaine\, 38 Rue Albert Marquet\, Bordeaux\, 33000\, France
CATEGORIES:home-event,Seminars
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