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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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TZID:Europe/Paris
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TZOFFSETFROM:+0100
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TZNAME:CEST
DTSTART:20230326T010000
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DTSTART:20231029T010000
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DTSTART;VALUE=DATE:20230619
DTEND;VALUE=DATE:20230707
DTSTAMP:20260411T015232
CREATED:20221118T145711Z
LAST-MODIFIED:20230707T071418Z
UID:152891-1687132800-1688687999@www.bordeaux-neurocampus.fr
SUMMARY:Cajal lectures: Glial cells in health and diseases
DESCRIPTION:\n\n\n\n\n\n\n\n\nVenue: CGFB \nOpen to everyone \n\nProgram\nJune 19 – 11:00am\nCourse directors talk:\nRagnhildur Thora Karadottir (Cambridge University\, UK)\, Cagla Eroglu (Duke University\, USA)\, Staci Bilbo (Duke University\, USA) and Jean-Christophe Delpech (NutriNeuro) \nJune 22 – 9:00am\nWiebke Moebius (Max-Planck Institute of Multidisciplinary Sciences\, Germany)\nExploring myelin biology with electron microscopy. \nJune 22 – 10:00am\n3 Brain : Presentation \nJune 22 – 11:00am\nAmit Agarwal (Heidelberg University\, Germany)\nDecoding calcium signals and mitochondrial dynamics in brain macroglia in vivo. \nJune 23 – 9:00am\nThomas Papouin (Washington University\, School of Medicine \, USA)\nMapping the Contribution of Astrocytes to the Effects of Neuromodulators on Synapses and Behavior. \nJune 23 – 11:00am (Virtual talk)\nMikael Simons (DZNE\, Germany)\nMechanisms of (re)myelination in the CNS. \nJune 24 – 9:00am\nCaroline Smith (Boston College\, USA)\nConducting rigorous behavioral testing in the context of neuro-immune interactions. \nJune 24 – 10:00am\nGiampaolo Milior (College de France\, France)\nGlial cells in the human brain: new insights and perspectives from work on human epileptic tissues. \nJune 26 – 9:00am\nKelly Monk (Vollume Institute\, USA)\nMolecular and genetic analysis of glial cell development. \nJune 26 – 11:00am\nMaarten Kole (Netherlands Institute for Neuroscience \, The Netherlands)\nNeuron-oligodendrocyte interactions in cortical circuits. \nJune 29 – 9:00am\nAddgene Presentation\nAddgene’s resources for neuroscience. \nJune 29 – 5:45pm (Virtual talk)\nDavid Rowitch (Cambridge University\, UK)\nHeterogenous origins of glia. \nJune 30 – 9:00am\nStéphane Oliet (Neurocentre Magendie\, Bordeaux University\, France)\nAstroglial contribution to NMDA receptor activity. \nJune 30 – 11:00am\nNathalie Rouach (Collège de France\, France)\nAstrocytes : the stars of brain plasticity. \nJuly 1 – 9:00am\nBart Eggen (UMCG/RUG\, The Netherlands)\nHuman microglia in development\, health and disease. \nJuly 3 – 9:00am\nSonia Garel (PSL University\, France)\nMicroglia in early brain wiring: from circuit assembly to tissue integrity \nJuly 3 – 11:00am\nEric Boué-Grabot (Bordeaux University\, France)\nSynaptic and microglial function of ATP P2X receptors in health and disease \nJuly 3 – 5:30pm (Virtual talk)\nPaola Arlotta (Harvard University\, USA)\nChanging neurons to shape glia: a tale of microglia and oligodendrocytes \nJuly 6 – 9:00am\nSoyong Hong (Dementia Research Institute\, University College London\, UK)\nMicroglia-synapse interactions: The triggers and the consequences. \nJuly 6 – 2:30pm\nDavid Belin (Cambridge Univeristy\, UK)\nRole of striatal astrocytes in the development of drug seeking habits \nJuly 6 – 4:00pm TDT Presentation  \nCourse Directors\nRagnhildur Thora Karadottir\, Cambridge University\, UK\n\n\n\n\n\n\n\n\n\n\n\n\n\nCagla Eroglu\, Duke University\, US \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nStaci Bilbo\, Duke University\, US \n\n\n\n\n\n\n\n\n\n\n\n\n\n\nJean-Christophe Delpech\, Bordeaux Neurocampus\, FR \nAbout the Cajal lectures\nThe Cajal lectures are organized in the frame of the Cajal courses\, located in the Bordeaux school of Neuroscience. They are open to everyone. \nMore details about this course:\nhttps://cajal-training.org/on-site/glial-and-astrocyte-cells-in-health-and-diseases/ \n  \n\n\n\n\n\n\n\n\n\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/cajal-lectures-glial-cells-in-health-and-diseases/
CATEGORIES:Cajal Lectures,For scientists,home-event
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DTSTART;TZID=Europe/Paris:20230619T140000
DTEND;TZID=Europe/Paris:20230619T150000
DTSTAMP:20260411T015232
CREATED:20230427T082057Z
LAST-MODIFIED:20230427T083422Z
UID:158564-1687183200-1687186800@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Yusuke Nasu
DESCRIPTION:Venue: Neurocentre Magendie – Conference room \n\nYusuke Nasu\nYusuke Nasu\nAssistant professor\nDepartment of Chemistry of the University of Tokyo \nInvited by Giovanni Marsicano (Neurocentre Magendie) \nTitle\nLACCO series: Genetically encoded fluorescent L-lactate biosensors for neuroscience \nAbstract\nOrganisms on Earth produce biologically-useful energy by catabolizing glucose to pyruvate which\, in the absence of oxygen\, is normally converted into L-lactate. Traditionally\, L-lactate has been considered “waste” by-products of glucose metabolism. However\, growing evidence suggests that L-lactate is better considered a biological “fuel currency”\, that can be shuttled from cell-to-cell and plays a central role in the energy supply for organisms. For example\, the astrocyte-to-neuron lactate shuttle (ANLS) hypothesis proposes that astrocytes metabolize glucose to produce L-lactate which is then released to the extracellular environment and taken up by neurons. In neurons\, L-lactate is converted to pyruvate which is fed into the tricarboxylic acid cycle (TCA) for production of adenosine triphosphate (ATP) which provides energy necessary to sustain heightened neural activity. The ANLS hypothesis remains a controversial mystery\, with recent reports of evidence both for and against it. \nFluorescent proteins (FPs) have been proven to be versatile scaffolds for development of biosensors (protein constructs that change their fluorescence intensity in response to changes in the environment). Specifically\, GCaMP\, a calcium ion (Ca2+) sensor based on green FP (GFP) and Ca2+ sensing domains\, has been widely employed to monitor neural activities in live model organisms. In addition to GCaMP\, various FP-based biosensors for non-Ca2+ target have been developed. However\, few sensors have sensitivity as high as GCaMP\, hampering their wide application in vivo. \nHerein\, we show that directed protein evolution can enable the engineering of FP-based biosensors for an important metabolite L-lactate with high sensitivity comparable to GCaMP. This study provides a powerful new optical toolbox\, LACCO series\, for the investigation of extracellular and intracellular L-lactate in neurons and astrocytes. We anticipate that the LACCO series will play a central role in investigations of L-lactate shuttles\, including the controversial ANLS hypothesis. \nBiosketch\nDr. Yusuke Nasu is an assistant professor in Robert E. Campbell’s lab at The University of Tokyo. His work focuses specifically on the protein engineering to develop high-performance genetically encoded fluorescent biosensors for neuroscience. In collaboration with neuroscientists\, he aims to address mysteries in brain by applying these biosensors to living model animals. \n  \n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-yusuke-nasu/
CATEGORIES:For scientists,home-event,Impromptu seminar
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20230619T173000
DTEND;TZID=Europe/Paris:20230619T173000
DTSTAMP:20260411T015232
CREATED:20230608T091606Z
LAST-MODIFIED:20230608T091606Z
UID:160273-1687195800-1687195800@www.bordeaux-neurocampus.fr
SUMMARY:Reproducibilitea session
DESCRIPTION:Venue: CGFB (Salle Sud) and on Zoom \nTopic : GENIGMA: an app to map the 3D genome of cancer celle lines through extreme citizen cience \nHost: Carmen Guerrero (Mallet – Leblois’ team – IMN) \n
URL:https://www.bordeaux-neurocampus.fr/en/event/reproducibilitea-session-15/
CATEGORIES:For scientists,home-event,Reproducibilitea session
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