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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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DTSTART:20210328T010000
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DTSTART;VALUE=DATE:20211122
DTEND;VALUE=DATE:20211209
DTSTAMP:20260408T213221
CREATED:20210322T093046Z
LAST-MODIFIED:20211207T220615Z
UID:133076-1637539200-1639007999@www.bordeaux-neurocampus.fr
SUMMARY:Cajal lectures: Optogenetics\, chemogenetics and biosensors for cellular and circuit neuroscience
DESCRIPTION:CGFB (all talks) or Centre Broca (Adam Packer\, December 3rd)\n \n\n\n\n\nLecture schedule\n\n\n\nNovember 24 – 9:00am \nStefan Herlitze ((University of Bochum\, Germany)\nOptogenetic control and visualization of GPCR pathways\, or a journey from mouse brain to bioluminescent fish \nNovember 24 – 11:00am\nJonas Wietek (Weizmann Institute of science\, Israel) \nNovember 25 – 9:00am \nTommaso Patriachi (University of Zurich\, Switzerland)\nGenetically encoded tools for high-resolution in vivo imaging of neuromodulator dynamics \nNovember 25 – 11:00\nMichael Lin (Stanford University\, USA) \nNovember 26 – 5:30pm  (remotely)\nAdam Cohen (Harvard University\, USA)\nOptical mapping of neural activity: from voltage imaging to time-tagged ticker tapes \nNovember 27 – 11:00am\nOfer Yizhar (Weizmann Institute of Science\, Israel) \nNovember 29 – 9:00am\nTom Kash (University of North Carolina\, USA) \nNovember 29 – 11:00am\nYaniv Ziv (Weizmann Institute of science\, Israel) \nDecember 2  – 9:00am\nValentina Emiliani (Institut de la vision\, France)\nHolographie manipulation of neuronal circuits \nDecember 2 – 11:00am \nStéphane Dieudonné (Aix-Marseille University\, France)\nA random-access strategy for all-optical recording and control of neuronal activity in vivo: how fast can we get? \nDecember 3 – 9:00am\nAnna Beyeler (Bordeaux Neurocampus\, France)\nCircuit dissection scope and limits: case studies of the amygdala and insular cortex \nDecember 3  – 11:00am\n Adam Packer (University of Oxford\, UK)\nAll-optical technologies for interrogation of neural codes and their transmission \nDecember 4 – 11:00am\nSimon Wiegert (Center for Molecular Neurobiology Hamburg – ZMNH\, Germany)\nIlluminating neuronal circuits: from new tools to synapses and networks \nDecember 6 – 9:00am\nTatiana Korotkova (University of Cologne\, Germany) \nDecember 8 – 3:30pm (remotely)\nNa Ji (University of Berkeley\, USA)\nImaging the brain at high spatiotemporal resolution \nDecember 8 – 5:30pm (remotely)\nUte Hochgeschwender (Central Michigan University) \n\n\n\n\n\n\n\n\nCourse overview\n\n\n\n\n\n\n\n\n\nSpatio-temporally precise manipulation and read-out of brain circuit function has been one of the longest-standing challenges in neuroscience. The recent explosion in the field of genetically encoded tools to control and measure neuronal activity has greatly facilitated investigation of brain function\, ranging from single synapses to large-scale circuits. Both control and readout of neuronal activity can now be achieved over orders of magnitude in space and time\, ranging from micrometers to entire brain regions and from milliseconds to days. \nThis course will provide participants with the opportunity to gain hands-on experience using the latest genetically encoded tools and state-of-the-art equipment for brain circuit investigation. A particular focus will lie on multiplexed manipulations and read-out of brain circuits. Participants will be familiarized with the biophysical principles behind the sensors and actuators\, and given training complementary to their background in the technical aspects of experimental approaches. \nHands-on experiments will employ optogenetic and chemogenetic actuators\, including excitatory and inhibitory ion channels\, pumps\, enzymes and G-protein coupled receptors. These actuators will be complemented by genetically encoded indicators of neural activity\, including calcium and voltage indicators as well as indicators for neurotransmitters and neuromodulators such as glutamate\, dopamine and norepinephrine. \nThe course will cover a wide range of experimental systems with an emphasis on functional brain circuits in vivo. Finally\, participants will be guided through data analysis and conceptual interpretations of their experiments. \n\n\nCourse directors\n\n\n\n\n\n\n\n\n\n\n\n\nOfer Yizhar\nCourse Director\nWeizmann Institute of Science – Israel \n\n\n\n\n\n\n\n\n\n\n\n\n\n\nMichael Lin\nCo-director\nStanford University – USA \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nSimon Wiegert\nCo-Director\nCenter for Molecular Neurobiology Hamburg (ZMNH) – Germany \n\n\n\n\n\n\n\n\n\n\n\n\n\n\nAnna Beyeler\nCo-director\nUniversity of Bordeaux – France \n\n\n\n\n\n\n\n\n\n\n\n\n\nMore details\nhttp://www.bordeaux-school-of-neuroscience.eu/trainings/cajal/cajal-2021/ocbccn-2021/ \n\n\n\n\n\n\n\n\n\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/cajal-lectures-ocbccn-2021/
CATEGORIES:For scientists,home-event,not-calendar
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20211123T110000
DTEND;TZID=Europe/Paris:20211123T120000
DTSTAMP:20260408T213221
CREATED:20211025T081956Z
LAST-MODIFIED:20211025T083238Z
UID:140267-1637665200-1637668800@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Julien Berro
DESCRIPTION:\n	\n		\n			Title\nForce production and force sensing during clathrin-mediated endocytosis \nAbstract\nClathrin-mediated endocytosis (CME) consists of the formation of a vesicle out of a flat membrane in eukaryotic cells. When membrane tension and/or turgor pressure are high\, actin dynamics is required to produce the forces required to invaginate the membrane and pinch it off into a vesicle. However\, how the actin meshwork produces forces at the molecular level has remained elusive\, because endocytic structures are transient\, out of equilibrium\, and diffraction limited. In this seminar\, I will present results from mathematical modeling and experiments in yeast showing that actin polymerization alone is not sufficient force to invaginate the plasma membrane. I will also present new force production mechanisms by the actin meshwork that are not exclusively based on polymerization\, and are relevant to other subcellular processes involving actin and membranes. \nSelected publications\nLemière J\, Ren Y\, Berro J (2021) Rapid adaptation of endocytosis\, exocytosis and eisosomes after an acute increase in membrane tension in yeast cells. eLife 10:e62084. \nMa R\, Berro J (2021) Endocytosis against high turgor pressure is made easier by partial coating and freely rotating base. Biophysical Journal 120:1625–1640. \nMartiel J-L\, Michelot A\, Boujemaa-Paterski R\, Blanchoin L\, Berro J (2020) Force Production by a Bundle of Growing Actin Filaments Is Limited by Its Mechanical Properties. Biophysical Journal 118:182–192. \nLacy MM\, Baddeley D\, Berro J (2019) Single-molecule turnover dynamics of actin and membrane coat proteins in clathrin-mediated endocytosis.  eLife 8:e52355. \nLacy MM\, Ma R\, Ravindra NG\, Berro J (2018) Molecular mechanisms of force production in clathrin-mediated endocytosis. FEBS Letters 592:3586–3605. \n\n		\n	\n\n	\n		\n			 \nDr. Julien Berro\nAssociate Professor of Molecular Biophysics\, Biochemistry\, and Cell Biology\nYale University School of Medicine \nhttps://medicine.yale.edu/profile/julien_berro \nInvited by \nDavid Perrais\nIINS \n\n		\n	\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-julien-berro/
CATEGORIES:For scientists,home-event,Impromptu seminar
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