BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Bordeaux Neurocampus - ECPv4.9.10//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
BEGIN:VTIMEZONE
TZID:Europe/Paris
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20210328T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20211031T010000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;VALUE=DATE:20210920
DTEND;VALUE=DATE:20211010
DTSTAMP:20260506T065548
CREATED:20191021T090540Z
LAST-MODIFIED:20211007T174709Z
UID:112212-1632096000-1633823999@www.bordeaux-neurocampus.fr
SUMMARY:Cajal course: Ageing cognition
DESCRIPTION:The lectures during the Cajal course are open to every member of Bordeaux Neurocampus. \nVenue: CGFB \n\nMonday 20 September – 14:00-15:30\nLuisa Lopes (Neurobiology of Ageing & Disease – iMM Lisboa\, Portugal) \nTuesday 21 September – 9:00-10:30\nCheryl Grady (The Rotman Research Institute\, Baycrest & University Toronto\, Canada) \nTuesday 21 September – 11:00-12:30\nNora Abrous (Neurocentre Magendie\, Bordeaux Neurocampus\, France) \nWednesday 22 September – 9:00-10:30\nCarol Barnes (University of Arizona\, USA) \nWednesday 22 September – 11:00-12:30 / remotely\nMaria Llorens-Martins (Universidad Autonoma Madrid\, Spain) \nFriday 24 September – 9:00-10:30\nLaure Rondi-Reig (Sorbonne Université\, Paris\, France) \nFriday 24 September – 11:00-12:30\nAline Marighetto (Neurocentre Magendie\, Bordeaux Neurocampus\, France) \nMonday 27 September – 17:00-18:30\nYaakov Stern (Columbia University\, USA) \nThursday 30 September – 11:00-12:30\nAdam Antebi (Max Planck Institute for Biology of Ageing\, Germany)  \nMonday 4 October – 9:00-10:30\nLuc Buée (University of Lille\, France) \nMonday 4 October- 11:00-12:30\nHélène Amieva (Bordeaux population Health Center\, France) \nTuesday 5 October – 9:00-10:30\nLars Nyberg (Umeå University\, Sweden) \nTuesday 5 October – 11:00-12:30\nGwenaelle Catheline (INCIA\, Bordeaux Neurocampus\, France) \n\nAbout the Cajal course\nVenue: Bordeaux School of Neuroscience \nThe normal aging process is associated with reduced performance on cognitive tasks that require one to quickly process or transform information to make a decision\, including measures of speed of processing\, executive cognitive function\, working and relational memories. Structural and functional alterations in the brain correlate with these age-related cognitive changes\, such as loss of synapses\, and dysfunction of neuronal networks. It is crucial to develop new approaches that consider the whole neuroanatomical\, endocrine\, immunological\, vascular and cellular changes impacting on cognition. \nThis 3-week course will cover the fundamentals of cognitive aging -including inter-individual differences\, cognitive and brain reserve and risk factors- and highlight the newest functional imaging methods to study human brain function. The Faculty will share the state-of-the-art molecular\, optical\, computational\, electrophysiological\, behavioural and epidemiological approaches available for studying the aging brain in diverse model systems. The Students will learn the potential and limitations of these methods\, through practical experience in a combination of lectures addressing aging in both humans and animal models and hands-on-projects. They will acquire sufficient practical experience to model\, design and interpret experiments and brainstorm on novel technologies and hypotheses to explore the aging of the brain using more integrative and creative approaches. \nCourse director\nLuísa Lopes\nNeurobiology of Ageing & Disease\niMM Lisboa\nPortugal \nCo-directors\nCheryl Grady\nThe Rotman Research Institute\, Baycrest\,\nCanada \nNora Abrous\nNeurocentre Magendie INSERM U 1215\,\nUniversity of Bordeaux\nFrance \nKeynote speakers\nHélène Amieva (Bordeaux Population Health\, France)\nAdam Antebi (Max Planck Institute for Biology of Ageing\, Germany)\nCarol Barnes (University of Arizona\, USA)\nLuc Buée (Centre de Recherche Jean-Pierre Aubert\, France)\nGwenaëlle Catheline (Bordeaux Neurocampus\, France)\nMaria Llorens (Centro de Biologia Molecular Severo Ochoa\, Spain)\nAline Marighetto (Bordeaux Neurocampus\, France)\nLars Nyberg (Umeå University\, Sweden)\nLaure Rondi-Reig (Sorbonne University\, France)\nYaakov Stern (Columbia University\, USA)\nTony Wyss-Coray (Stanford University\, USA) \nMore details\nhttp://cajal-training.org/on-site/ageing-cognition/ \n
URL:https://www.bordeaux-neurocampus.fr/en/event/cajal-course-ageing-cognition/
CATEGORIES:For scientists,Trainings
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20211001T140000
DTEND;TZID=Europe/Paris:20211001T140000
DTSTAMP:20260506T065548
CREATED:20210526T085549Z
LAST-MODIFIED:20210908T103959Z
UID:135322-1633096800-1633096800@www.bordeaux-neurocampus.fr
SUMMARY:Monthly conference (PhD seminar) - Vladan Lucic
DESCRIPTION:\n	\n		\n			Centre Broca Nouvelle-Aquitaine \n\n\n		\n	\n\n	\n		\n			Title : Architecture of trans-synaptic assemblies at the single nanometer scale. \nNeurotransmitter release is mediated by a complex and highly regulated molecular machinery. We imaged isolated synapses by cryo-electron tomography (cryo-ET)\, a method that utilizes faithful sample preservation and direct 3D imaging of fully hydrated\, unlabeled biological material at 2-4 nanometer resolution. The computational procedures for template-free detection and classification in cryo-tomograms that we developed allowed us to quantitatively analyze the spatial organization and inter-relation of synaptic complexes. We showed that tripartite trans-synaptic assemblies (subcolumns) link synaptic vesicles to postsynaptic ionotropic glutamate receptors\, and established that a particular displacement between the interacting complexes characterizes subcolumns. Furthermore\, we obtained de novo average structures of ionotropic glutamate receptors in their physiological composition\, embedded in plasma membrane. In a separate set experiments\, we found that Munc13 and SNAP25\, proteins known to be essential for synaptic vesicle priming for release and fusion\, control the location of synaptic vesicles at a single nanometer precision by tethering them to the plasma membrane\, resulting in two stable primed vesicle states. Furthermore\, these two proteins\, together with protein kinase C\, control the transition between the two primed states by coordinated reorganization of both tethers and molecular bridges (connectors) that interlink vesicles. Together\, our data supports the hypothesis that synaptic transmission is carried by precisely aligned trans-synaptic units that are organized in large molecular assemblies of variable architecture. \nPublications\nMartinez-Sanchez wt al.\, 2021. Trans-synaptic assemblies link synaptic vesicles and neuroreceptors. Science advances\n7: eabe6204. \nMartinez-Sanchez et al.\, 2020. Template-free detection and classification of membrane-\nbound complexes in cryo-electron tomograms. Nature methods 17:209–216. \nZuber\, B.\, and V. Lucic\, 2019. Molecular architecture of the presynaptic terminal. Current opinion\nin structural biology 54:129–138. \n\nOrganized by Bordeaux Neurocampus\, NBA and Bordeaux Neurocampus Graduate Program \n\n		\n	\n\n	\n		\n			 \nVladan Lucic\nProject Group Leader\nResearch Department Molecular Structural Biology\nMax Planck Institute of Biochemistry\nMartinsried\, Munich\, Germany \nhttps://www.biochem.mpg.de/7416282/dr-vladan-lucic \n\n		\n	\nShare a pizza with the speaker\n\n	\n		\n			Ph.D. students are invited to a networking event with the guest speaker around some pizzas. \nDeadline to register: 48h prior the event\nRegistration form \nNote: According to the legislation in vigour\, you may be requested to show your sanitary pass to attend this event \n  \n\n		\n	\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/phd-seminar-october-2021/
CATEGORIES:For scientists,home-event,Monthly conferences
ATTACH;FMTTYPE=image/jpeg:https://www.bordeaux-neurocampus.fr/wp-content/uploads/2021/05/lucic-vladan-vign.jpg
END:VEVENT
END:VCALENDAR