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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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DTSTART:20250330T010000
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DTSTART;VALUE=DATE:20251124
DTEND;VALUE=DATE:20251206
DTSTAMP:20260530T123548
CREATED:20250221T135325Z
LAST-MODIFIED:20251205T164224Z
UID:181025-1763942400-1764979199@www.bordeaux-neurocampus.fr
SUMMARY:Cajal lectures: "Neuroimmunology in Physiology and Disease: From Fundamental Concepts to Hands-on Training"
DESCRIPTION:Venue : CARF \nOrganized by the Bordeaux School of Neuroscience. \nLectures are open to everyone. \n\nNovember 26 – 9:00am \nSonia Garel (Institut de Biologie de l’École Normale Supérieure\, France)\nMicroglia in early brain construction. \nNovember 26 – 11:00am\n Michael Heneka (Luxemburg University\, Luxemburg)\nTunneling nanotubes as rescue routes between microglia and neurons \nNovember 27 – 9:00am \nAndrew Greenhalgh (University of Manchester\, UK)\nNavigating a career in neuroimmunology. \nNovember 28 – 9:00am \n Renzo Mancuso  (VIB\, Antwerp\, Belgium)\nElucidating the role of human microglia in neurodegeneration \nNovember 28 – 11:00am \nArthur Liesz (Ludwig-Maximilians Munich University\, Germany)\nImmunological brain-body interaction after stroke. \nDecember 1 – 9:00am \nRejuane Rua (Centre d’Immunologie de Marseille Luminy\, France)\nBrain border macrophages : more than immune sentinels? \nDecember 3 – 9:00am \nMichal Schwartz (Weizmann Institute of Science\, Israel)\nTBA \nDecember 3 – 11:00am \nAleksandra Deczkowska (Institut Pasteur\, France)\nImmune regulation of brain physiology. \nDecember 5 – 9:00am \nLaurent Groc (University of Bordeaux\, CNRS\, France)\nDecrypting pathogenic brain autoantibody at the molecular level. \nDecember 4 – 5:00pm \nJonathan Kipnis (Washington University School of Medicine\, USA)\nWhat is CNS immune privilege? An update. \nCourse Directors \n\nRosa Chiara Paolicelli – University of Lausanne\, Switzerland\nAgnes Nadjar – Neurocentre Magendie\, University of Bordeaux\, France\nStefano Pluchino – University of Cambridge\, UK\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/cajal-lectures-neuroimmunology-in-physiology-and-disease-from-fundamental-concepts-to-hands-on-training/
CATEGORIES:Cajal Lectures,For scientists
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251201T110000
DTEND;TZID=Europe/Paris:20251201T110000
DTSTAMP:20260530T123548
CREATED:20250826T082825Z
LAST-MODIFIED:20250908T164104Z
UID:187019-1764586800-1764586800@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Anne-Noël Samaha
DESCRIPTION:Venue: Centre Broca \n\nAnne-Noël Samaha\nUniversité de Montréal\nhttps://fr.samaha-lab.com/\n \nInvited by Claudia Fornari and Céline Nicolas (INCIA) \nTitle\nOn Modelling Cocaine Addiction in Rats \nAbstract\nA widely used preclinical procedure to study features of cocaine addiction involves allowing laboratory animals to take drug continuously\, for hours each day. However\, data in human cocaine users suggest that cocaine use may typically be intermittent\, rather than continuous. Here I will present surprising findings concerning the effects of intermittent versus continuous cocaine intake in rats. As it turns out\, less is more\, and intermittent cocaine use is especially effective in producing addiction-relevant patterns of cocaine seeking and taking. \nSelected publications\nAmphetamine maintenance therapy during intermittent cocaine self-administration in rats attenuates psychomotor and dopamine sensitization and reduces addiction-like behavior. Florence Allain\, Benoît Delignat-Lavaud\, Marie-Pierre Beaudoin\, Vincent Jacquemet\, Terry.E Robinson Louis-Eric Trudeau and Anne-Noël Samaha. Neuropsychopharmacology\, 2021 \nThe transition to cocaine addiction: the importance of pharmacokinetics for preclinical models. Alex B. Kawa\, Florence Allain\, Terry E. Robinson and Anne-Noël Samaha. Psychopharmacology\, 2019 \nRevisiting long-access versus short-access cocaine self-administration in rats: intermittent intake promotes addiction symptoms independent of session length. Florence Allain and Anne-Noël Samaha. Addiction Biology\, 2018 \nHigh and escalating levels of cocaine intake are dissociable from subsequent incentive motivation for the drug in rats. Florence Allain\, Karim Bouayad-Gervais and Anne-Noël Samaha. Psychopharmacology\, 2018 \nHow fast and how often: The pharmacokinetics of drug use are decisive in addiction. Florence Allain\, Ellie-Anna Minogianis\, David C.S. Roberts and Anne-Noël Samaha. Neuroscience and Biobehavioral Reviews\, 2015. \n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-anne-noel-samaha/
CATEGORIES:For scientists,home-event,Impromptu seminar
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251201T113000
DTEND;TZID=Europe/Paris:20251201T140000
DTSTAMP:20260530T123548
CREATED:20251126T190114Z
LAST-MODIFIED:20251126T190137Z
UID:190125-1764588600-1764597600@www.bordeaux-neurocampus.fr
SUMMARY:Marché de Noël
DESCRIPTION:Lieu : hall de l’institut Magendie \n\nOrganisé par le CLAS Inserm Nouvelle-Aquitaine \n \n  \n
URL:https://www.bordeaux-neurocampus.fr/en/event/marche-de-noel-2025/
CATEGORIES:Entre nous,home-event
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251201T143000
DTEND;TZID=Europe/Paris:20251201T143000
DTSTAMP:20260530T123548
CREATED:20251023T081907Z
LAST-MODIFIED:20251103T165446Z
UID:189220-1764599400-1764599400@www.bordeaux-neurocampus.fr
SUMMARY:Thesis defense - Claudia Fornari
DESCRIPTION:Venue: BBS \n\nClaudia Fornari\néquipe :Addiction\, Intéroception et dimorphisme sexuel (NEED)\nCéline Nicolas INCIA \nTitle\nNeurobiological and Hormonal Mechanisms of Sex Differences in Alcohol Consumption and Cocaine Relapse in rodents \nAbstract\nAddiction is characterized by persistent drug use despite negative consequences and a high risk of relapse\, two major obstacles to its treatment. Both clinical and preclinical research have consistently reported sex differences in alcohol consumption and cocaine relapse. However\, the neurobiological mechanisms driving these differences are still poorly understood. \nOver the past decade\, the prevalence of alcohol use disorders increased in both men and women\, but more dramatically among women\, emphasizing the need to investigate sex-specific neural mechanisms underlying alcohol addiction. In this context\, the first objective of my thesis was to elucidate sex differences in antero-posterior insular cortex function during persistent alcohol consumption despite aversion in mice. At the behavioral level\, we revealed that females had a higher persistent ethanol intake compared to males\, and this effect was independent of the hormonal cycle. At the neuronal level\, using fiber photometry recordings\, we showed that glutamatergic neurons of the anterior insular cortex (or insula) increased their activity during persistent ethanol intake independently of sex. Furthermore\, chemogenetic inhibition of anterior insula neurons significantly reduced persistent ethanol intake in both males and females. In contrast\, activity of posterior insula excitatory neurons was increased during persistent ethanol drinking exclusively in females\, and inhibition of this neuronal population selectively reduced persistent ethanol intake in females. Together\, our findings reveal an antero-posterior and sex-dependent insular function in the regulation of persistent ethanol drinking in mice. \nIn the context of cocaine relapse\, previous studies suggested that relapse vulnerability fluctuates across the female hormonal cycle\, especially in the context of cue-induced cocaine relapse. In this context\, progesterone has emerged as a potential protective factor. Thus\, the second axis of my PhD deciphered the behavioral and neurobiological mechanisms underlying progesterone’s effect on cue-induced cocaine relapse in female rats.  We demonstrated that females with low endogenous progesterone levels have a greater level of relapse than those with high levels\, indicating a protective role of this hormone. Moreover\, acute progesterone treatment markedly reduced relapse in vulnerable females. By quantifying the neuronal activity marker cFos in several brain regions involved in drug relapse\, we highlighted that progesterone treatment in vulnerable females\, decreased the neuronal activation of the posterior insula and the central amygdala\, demonstrating that they could be key neuronal target of progesterone’s protective effect. Finally\, relapse levels positively correlate with the number of cFos-positive neurons in the posterior insula and the central amygdala\, and progesterone abolished this correlation. Collectively\, our results provide a solid foundation for understanding the neuronal basis underlying progesterone protective effects on relapse vulnerability in females. \nKeywords: Drug addiction\, Sex differences\, Hormonal cycle \nPublication\nClaudia Fornari\, Carmen Guerrero-Márquez\, Praneeth Namburi\, Yoni Couderc\, Céline Nicolas* and Anna Beyeler*. Sexual dimorphism of posterior insular cortex function in alcohol drinking despite aversion in mice. BioRxiv 2023 and under revision. \nJury\n\nStéphanie DAUMAS – Professeure – CNRS\, Sorbonne Université\, France – Présidente\nLiana FATTORE – Senior research scientist – Istituto di Neuroscienze\, Italie –  Rapportrice\nAnne-Noël SAMAHA  Professeure – Université de Montréal\, Canada – Rapportrice\nFrançois GEORGES – Directeur de recherche – CNRS\, Université de Bordeaux\, France – Examinateur\nFuschia SERRE – Chercheure – Université de Bordeaux\, France – Examinatrice\nCéline NICOLAS – Chargée de recherche – CNRS\, Université de Bordeaux\, France – Directrice de thèse\nAnna BEYELER – Invitée\n\n  \n
URL:https://www.bordeaux-neurocampus.fr/en/event/thesis-defense-claudia-fornari/
CATEGORIES:Thesis
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