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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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TZID:Europe/Paris
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TZNAME:CEST
DTSTART:20250330T010000
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DTSTART:20251026T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20251118
DTEND;VALUE=DATE:20251119
DTSTAMP:20260421T151620
CREATED:20250425T132606Z
LAST-MODIFIED:20251118T215139Z
UID:183411-1763424000-1763510399@www.bordeaux-neurocampus.fr
SUMMARY:Symposium - "Research on the Biology and Diseases of Ageing in Bordeaux"
DESCRIPTION:Venue: Amphi Louis\, ISPED\, Carreire campus\, University of Bordeaux.  \n\nLife expectancy is increasing\, yet ageing inevitably brings a higher risk of various illnesses\, including cancer\, cardiovascular diseases\, neurodegenerative disorders\, metabolic conditions\, and infections. Several research teams at the University of Bordeaux are dedicated to better understanding the mechanisms behind these age-related comorbidities and exploring strategies to prevent or treat them. Their ultimate goal is to slow the effects of ageing and enhance the quality of life for older adults. \nBuilding on the successes of the 2023 and 2024 symposiums\, the Bordeaux ageing research community is organizing its third symposium this year. This event will foster the exchange of scientific knowledge\, keep the community informed about the latest advances\, and promote interdisciplinary collaboration. \nEveryone is most welcome to attend this event. \nOrganizing committee: Nora Abrous\, Hélène Amieva\, Victor Appay\, Isabelle Bourdel-Marchasson\, Gwenaëlle Catheline\, Julie Dechanet Merville\, Alain Pierre Gadeau\, Catherine Helmer\, Maël Lemoine\, Olivier Mansier\, Isabelle Pellegrin\, Hamid-Reza Rezvani\, Claire Roubaud\, Virginie Postal\, Muriel Priault\, Katie Sawai\, Pierre Soubeyran. \nDownload the program (pdf) \n
URL:https://www.bordeaux-neurocampus.fr/en/event/symposium-approche-holistique-du-vieillissement-de-la-molecule-a-la-societe/
CATEGORIES:For scientists,Symposium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251118T083000
DTEND;TZID=Europe/Paris:20251118T170000
DTSTAMP:20260421T151620
CREATED:20250926T142554Z
LAST-MODIFIED:20251002T155848Z
UID:188281-1763454600-1763485200@www.bordeaux-neurocampus.fr
SUMMARY:2e édition LabCom Bordeaux : partenariats public-privé.
DESCRIPTION:Lieu : Bordeaux INP\navenue des Facultés\, 33400 Talence \n\nVous êtes impliqué dans des collaborations de recherche public-privé ou souhaitez le devenir ? Venez découvrir comment les renforcer et les développer grâce au format laboratoire commun (LabCom)\, à travers des partages d’expérience\, regards croisés\, présentations de dispositifs et temps de réseautage. \nProgramme\n8h30 : accueil café \n9h – 12h30 : plénières \n\nStratégie de développement des LabCom sur le site bordelais et les ambitions régionales\nIntervenants : Etienne Duguet\, vice-président en charge de l’innovation à l’université de Bordeaux ; Medhi Gmar\, directeur général délégué à l’innovation du CNRS ; Guillaume Ferré\, directeur général de Bordeaux INP ; Nicolas Roussel\, directeur du centre Inria de l’université de Bordeaux\nRegards croisés d’acteurs académiques et industriels sur les bénéfices concrets du format LabCom\nIntervenants : binôme LabCom TRICORN – John Lopez (CELIA) et Clemens Hoenninger (Amplitude) ; binôme LabCom ANR RedoxWine – Stéphane Arbault (CBMN) et Virginie Moine (Biolaffort) ; Gérard Vignoles (LCTS)\nPanorama des dispositifs de financement avec présentation des outils\nIntervenants : Sylvain Caillol – ANR ; Pascal Giat – ANRT ; Hélène Boisserie – Région Nouvelle-Aquitaine ; Natalia Araujo – BPI ; Camille Leborgne – Offre de service Europe ; Charlyne Quercia – Fondation Bordeaux Université\nFocus sur l’accompagnement proposé\, de la création au renouvellement du LabCom\nIntervenants : Détection – Anne-Laure Dinel (LabCom Seamind / NutriBrain) ; Montage / Contractualisation – Tristan Richard (LabCom Biophysa) / David Gaudout (Activ’Inside) / Mathilde Vasse (UB) ; Vie et suivi – Pierre Passot (Airbus\, EPC CONCACE) / Paola Torres (Inria) ; Renouvellement – Baptiste Batelier (LabCom iXatom)\n\n12h30 : cocktail déjeunatoire et réseautage \n13h45 – 16h45 : sessions thématiques\, approfondissez un ou deux sujets (au choix)\, posez vos questions aux experts et bénéficiez de retours d’expérience de vos pairs. \nSessions ouvertes à tous (1h15 chacune) : \n\nFinancements ANR : comment maximiser ses chances de succès ?\nFinancements européens pour LabCom : fonctionnement et opportunités\nAnimation d’un LabCom : comment le faire vivre ?\n\nSession réservée aux services d’accompagnement et de développement des LabCom (3h) : \n\nLabCom et SHS : initiatives en cours à l’échelle nationale\n\n16h45 : café de clôture \nInscription\nCet événement est accessible uniquement sur inscription. Les places en sessions thématiques sont limitées\, inscrivez-vous vite ! \nPour toutes questions\, envoyez un e-mail à labcombordeaux@u-bordeaux.fr \n\nRétrospective sur la 1ère édition\, à l’IOGS (Talence) :\nhttps://www.youtube.com/watch?v=QC2xk5KUMyU \nCette journée est organisée en collaboration avec l’université de Bordeaux\, le CNRS\, Bordeaux INP\, Inria\, Inrae\, Adera et Aquitaine Science Transfert. \nCet événement a bénéficié d’une aide de l’Etat gérée par l’Agence Nationale de la Recherche au titre du Plan France 2030\, portant la référence ANR-21-EXES-0004. \n
URL:https://www.bordeaux-neurocampus.fr/en/event/2e-edition-labcom-bordeaux-partenariats-public-prive/
CATEGORIES:For scientists,home-event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251118T110000
DTEND;TZID=Europe/Paris:20251118T110000
DTSTAMP:20260421T151620
CREATED:20251104T164339Z
LAST-MODIFIED:20251110T184954Z
UID:189260-1763463600-1763463600@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Gian-Carlo Bellenchi
DESCRIPTION:Venue: Centre Broca \n\nGian-Carlo Bellenchi\nInstitute of Biochemistry and Cell Biology IBBC-CNR\,\nMonterotondo\, Rome\, Italy.\nSanta Lucia Foundation IRCCS\, Rome\, Italy. \nInvited by Etienne Herzog (IINS) \nTitle\nThe Contribution of microRNAs to the Development and Function of Dopaminergic Neurons \nAbstract\nThe development and function of midbrain dopaminergic neurons (DAn) rely on tightly coordinated molecular programs involving both transcriptional and post-transcriptional regulation. While morphogens and transcription factors are well-established drivers of DAn specification\, the contribution of microRNAs (miRNAs) to these processes has only recently begun to emerge. Using paired miRNA–mRNA profiling during dopaminergic differentiation\, we identified miR-34b/c and miR-218 as key post-transcriptional regulators shaping DAn identity and function. miR-34b/c promotes dopaminergic lineage commitment and differentiation during embryonic development\, at least in part through modulation of Wnt1 signaling. In parallel\, miR-218 facilitates the functional maturation of DAn\, and its conditional deletion alters the expression of synaptic-related transcripts\, disrupts intrinsic excitability\, and reduces stimulus-evoked dopamine release. Together\, these findings highlight miRNA–mRNA co-regulatory networks as integral components of dopaminergic neuron development and physiology\, and position miRNAs as essential hubs orchestrating dopaminergic differentiation and neurotransmission. \nRelated Articles\nPulcrano S\, et al. miR-218 Regulates the Excitability of VTA Dopamine Neurons and the Mesoaccumbens Pathway in Mice. Brain Sci. 2025 \nTaylor SR\, et al. MicroRNA-218 instructs proper assembly of hippocampal networks. Elife. 2023 \nPulcrano S\, et al. miR-218 Promotes Dopaminergic Differentiation and Controls Neuron Excitability and Neurotransmitter Release through the Regulation of a Synaptic-Related Genes Network. J Neurosci. 2023 \nPulcrano S\, et al.  Lmx1a-Dependent Activation of miR-204/211 Controls the Timing of Nurr1-Mediated Dopaminergic Differentiation. Int J Mol Sci. 2022 \nDe Gregorio R\, et al. miR-34b/c Regulates Wnt1 and Enhances Mesencephalic Dopaminergic Neuron Differentiation. Stem Cell Reports. 2018 \n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-gian-carlo-bellenchi/
CATEGORIES:For scientists,home-event,Impromptu seminar
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251118T130000
DTEND;TZID=Europe/Paris:20251118T130000
DTSTAMP:20260421T151620
CREATED:20251107T142156Z
LAST-MODIFIED:20251107T142156Z
UID:189448-1763470800-1763470800@www.bordeaux-neurocampus.fr
SUMMARY:Santé mentale\, dépression et thérapies psychédéliques
DESCRIPTION:Dans le cadre de la 29ème Semaine européenne pour l’emploi des personnes handicapées (SEEPH)\, Vanessa Michel\, votre correspondante handicap\, vous propose 2 évènements les 18 et 20 novembre 2025.\nMardi 18 novembre : Conférence sur la “Santé mentale\, dépression et thérapies psychédéliques” – Et si l’on repensait la santé mentale autrement ? \nDans cette conférence\, Julie Dachez\, docteure en psychologie sociale\, proposera de replacer la santé mentale au coeur de la santé\, avec un focus sur la dépression : son étiologie multifactorielle\, ses manifestations\, et ses modalités de prise en charge\, en particulier les thérapies psychédéliques. Longtemps stigmatisées et criminalisées\, ces substances font aujourd’hui l’objet de nombreuses recherches et constituent une piste prometteuse dans le traitement de la dépression\, mais aussi des addictions et du stress post-traumatique. \nInfos pratiques \nMardi 18 novembre de 13h à 14h30\nEn présentiel: Inria Bordeaux\, salle Ada Lovelace\nEn visio:  https://inria.webex.com/inria/j.php?MTID=m47d77f9e57916388d89cc538c9d6857c \nVoir aussi:\nhttps://therapies-psychedeliques.fr/ \n
URL:https://www.bordeaux-neurocampus.fr/en/event/sante-mentale-depression-et-therapies-psychedeliques/
CATEGORIES:Events for all,IMN
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251118T143000
DTEND;TZID=Europe/Paris:20251118T143000
DTSTAMP:20260421T151620
CREATED:20250416T064832Z
LAST-MODIFIED:20251022T125935Z
UID:183086-1763476200-1763476200@www.bordeaux-neurocampus.fr
SUMMARY:Thesis defense - Ihssane Idrissi
DESCRIPTION:Venue : Centre Broca \n\nIhssane Idrissi \nTeam : Quantitative imaging of the cell\nIINS \nTitle\nDevelopment of a toxicology assay using 3D cellular models and soSPIM-based high-content screening \nAbstract\nDrug-induced liver injury (DILI) remains a major cause of drug withdrawal\, highlighting the urgent need for predictive and physiologically relevant in vitro assays. Three-dimensional (3D) cell cultures have emerged as promising models for drug screening and toxicity testing\, as they better reproduce tissue architecture and function compared to conventional two-dimensional (2D) systems. However\, their integration into high-content screening (HCS) still faces important challenges\, including the standardization and parallelization of culture\, the minimization of handling steps between culture and imaging\, and the development of imaging methods capable of capturing complete 3D volumes with high speed and minimal photobleaching and phototoxicity\, while remaining fully compatible with HCS requirements. \nThis PhD project aims to establish a dedicated HCS pipeline for hepatotoxicity assays using HepaRG liver spheroids\, microfabricated JeWells culture devices\, single-objective light-sheet fluorescence microscopy (soSPIM)\, and dedicated analysis tools. The soSPIM architecture\, based on integrated 45° mirrors\, enables high-speed\, low-phototoxic 3D imaging. Combined with JeWells devices\, arrays of truncated pyramidal-shaped cavities\, it allows the parallelized culture and standardized imaging of hundreds of 3D samples within a single chip\, providing quantitative morphological readouts at the single-organoid level. \nAs a proof of concept\, we modeled drug-induced cholestasis on 7-day-old HepaRG spheroids cultured in JeWell devices. Spheroids were exposed to reference compounds\, including chlorpromazine and indomethacin\, imaged on the soSPIM-HCS platform after immunolabelling\, and analyzed for nuclear\, cytoskeletal\, and hepatobiliary transporter markers. We demonstrated the ability of this platform to capture both morphological disruptions and functional impairments characteristic of cholestatic injury in liver organoids. \nOverall\, this work establishes a methodological framework integrating standardized 3D culture\, advanced 3D imaging\, and automated analysis into a single HCS pipeline for hepatotoxicity assessment. Beyond the case study of cholestasis\, this platform paves the way for broader applications of 3D organoid-based assays in drug discovery and toxicology. \nKeywords: Light-sheet microscopy\, HepaRG spheroids\, High-Content Screening\, Hepatotoxicity\, Cholestasis\, Quantitative image analysis. \nJury\nJean-Baptiste Sibarita  – Ingénieur de Recherche\, Université de Bordeaux\, CNRS – Directeur de Thèse \nCharlotte Rivière – Directrice de Recherche\, Université de Lyon\, CNRS – Rapporteure \nCorinne Lorenzo –  Ingénieure de Recherche\, Université de Toulouse\, CNRS – Rapporteure \nPierre Nassoy – Directeur de Recherche\, Université de Bordeaux\, CNRS – Examinateur \nPascale Roux – Lab Manager\, Sanofi – Invitée \nRémi Galland – Chargé de Recherche\, Université de Bordeaux\, CNRS – Invité \n
URL:https://www.bordeaux-neurocampus.fr/en/event/thesis-defense-ihssane-idrissi/
CATEGORIES:Thesis
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