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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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TZID:Europe/Paris
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TZNAME:CEST
DTSTART:20250330T010000
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DTSTART:20251026T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20250922
DTEND;VALUE=DATE:20251011
DTSTAMP:20260526T072512
CREATED:20250221T135021Z
LAST-MODIFIED:20251009T092733Z
UID:181026-1758499200-1760140799@www.bordeaux-neurocampus.fr
SUMMARY:Cajal lectures: "Cancer and Neuroscience"
DESCRIPTION:Venue : CARF \nOrganized by the Bordeaux School of Neuroscience. \nLectures are open to everyone. \n\n\n\nProgramme\n\n\n\n\nMonday 22 September – 11:00am\nAnna Golebiewska (Luxembourg Institute of Health\, Luxembourg)\nHeterogeneity and plasticity of the brain tumor ecosystem: What can we learn from advanced patient-derived models? \nTuesday 23 September – 9:00am\nSimona Parrinello (University College London\, UK)\nInjury programmes shape gliomagenesis. \nTuesday 23 September – 11:00am\nHenrik Heiland (Dep. of Neurosurgery\, University Clinic Erlangen\, Germany)\nTBA\n \nThursday 25 September – 9:00am\n Hélène Castel (Cancer and Brain Genomics\, Inserm\, University of Rouen\, France)\nNeurosciences in Oncology: When Cancer Thinks Out of the Box. \nThursday 25 September – 11:00am \nThomas Daubon (CNRS\, University of Bordeaux\, France)\nLactate Shuttle between Glioblastoma Cells and Neurons: a Cancer Neuroscience Case. \nMonday 29 September – 9:00am\nFranck Winkler (University of Heidelberg\, Germany)\nCancer Neuroscience of Brain Tumors. \nMonday 29 September – 11:00am \nVidhya M. Ravi (Medical Centre University Clinic of Freiburg\, Germany)\nTumor–Host Interdependence: Decoding the Microenvironmental Dialogue. \nThursday 2 October – 9:00am \nHrvoye Miletic (University of Bergen\, Norway)\nCell communication and mitochondria transfer in brain tumors. \nThursday 2 October – 11:00am\nManuel Valiente (Spanish National Cancer Research Centre\, Spain)\nThe Evolving Landscape of Brain Metastases. \nFriday 3 October – 9:00am\nLeila Akkari (Netherlands Cancer Institute\, The Netherlands)\nMacrophages: Jack of all Trades in the Brain Ecosystem? \nMonday 6 October – 9:00am\nVarun Venkataramani (German Cancer Research Center\, Germany)\nTBA \nOctober 6 – 11:00am\nAurélie Tchoghandjian (Institute of Neurophysiopathology\, Marseille\, France)\nGlioblastoma stemness and immunosuppression: breaking the lethal cycle. \nOctober 9 – 9:00am\nAntonio Pagano Zottola (Bordeaux Institute of Oncology\, University of Bordeaux\, France)\nMitoDREADD: a new mitochondria-specific chemogenetic tool. \n\n\n\nCourse Directors \n\nAnna Golebiewska – Luxembourg Institute of Health\, Luxembourg\nAntonio C. Pagano Zottola – Bordeaux Institute of Oncology – Inserm\, France\nVarun Venkataramani – Universität Heidelberg\, Germany\n\n\nMore details about the course \n
URL:https://www.bordeaux-neurocampus.fr/en/event/cajal-lectures-cancer-and-neuroscience/
CATEGORIES:Cajal Lectures,For scientists
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20251001
DTEND;VALUE=DATE:20251004
DTSTAMP:20260526T072512
CREATED:20240606T094411Z
LAST-MODIFIED:20240606T114607Z
UID:172091-1759276800-1759535999@www.bordeaux-neurocampus.fr
SUMMARY:BrainConf BrainBody : Exploring bidirectional crosstalk between the central nervous system and the body
DESCRIPTION:Venue : Centre Broca Nouvelle-Aquitaine \n\n11th Bordeaux Neurocampus Conference \nSupport us and benefit from visibility among our 150 attendants and Bordeaux Neurocampus community. \nSpeakers :\nZachary A. Knight (USA)\nMichael Brecht (DE)\nAnn Clemens (UK)\nAna Domingos (UK)\nIvan E. de Araujo (DE)\nGerard Eberl (FR)\nAmaury François (FR)\nIlana Gabanyi (PT)\nGiuseppe Gangarossa (FR)\nChristelle Glangetas (FR)\nNadine Gogolla (DE)\nAli Jawaid (PL)\nYoav Livneh (IL)\nArianna Maffei (USA)\nClaire Martin (FR)\nEnrica Montalban (FR)\nAgnès Nadjar (FR)\nFrancesco Pappaleo (IT)\nThomas Pradeu (FR)\nAsya Rolls (IL)\nLisa Roux (FR)\nDana Small (USA)\nCatherine Tallon-Baudry (FR) \nOrganizing commitee\nMario Carta (CNRS\, IINS)\nFrançois Georges (CNRS\, IMN)\nChristelle Glangetas (IMN)\nEnrica Montablan (NutriNeuro)\nAgnès Nadjar (Univ. Bordeaux\, Neurocentre Magendie) \nRegistration fees – early birds\nOpening of registration : April 15th\, 2025. \n\nStudent (Master\, PhD student) from the University of Bordeaux or from a speakers’s lab (Special fee *) : 110€ tax-free\nStudent (Master\, PhD student) from another lab : 160€ tax-free\nPostDoc from the University of Bordeaux or from a speakers’s lab (Special fee*) : 120€ all tax included\nPostDoc from another lab : 180€ all tax included\nSenior Scientist\, engineer and academic from the University of Bordeaux or from a speakers’s lab (Special fee*) : 180€ all tax included\nSenior Scientist\, engineer and academic from another lab : 300€ all tax included\n** Industrial : 360€ all tax included\n\n* Special fee for members of the university of Bordeaux or in some invited speaker’s lab \n** The registration of an industrial does not include the purchase of a stand or the logo in the event communication. If you wish to reserve a booth or have you logo visible\, please contact us or go to the sponsorship webpage. \nSponsors\nMore details soon \nTo check our former editions\nbrainconf.u-bordeaux.fr \nContact\nbrainconf@u-bordeaux.fr \n
URL:https://www.bordeaux-neurocampus.fr/en/event/brainconf-brainbody-exploring-bidirectional-crosstalk-between-the-central-nervous-system-and-the-body/
CATEGORIES:For scientists
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251001T093000
DTEND;TZID=Europe/Paris:20251001T093000
DTSTAMP:20260526T072512
CREATED:20250428T073914Z
LAST-MODIFIED:20250826T135824Z
UID:183462-1759311000-1759311000@www.bordeaux-neurocampus.fr
SUMMARY:Thesis defense - Violeta Milanovic
DESCRIPTION:Venue : CARF \nVideoconference link: https://u-bordeaux-fr.zoom.us/j/83185319457 \nDefense in English \n\nVioleta Milanovic\nTeam : Mechano-biology of motile and neuronal structures\nIINS \nThesis supervisor : Olivier Rossier \nTitle\nStudying cellular mechanotransduction in living cells using single molecule fluorescence polarization microscopy \nAbstract\nMechanotransduction\, the process by which mechanical forces are converted into biochemical signals\, is fundamental to cellular adhesion\, migration\, and the spatial organization and integrity of tissues. Integrin adhesion sites (IAS) serve as the mechanical interface between the extracellular matrix and the cytoskeleton\, and host a complex network of force-sensitive proteins such as talin. Key protein in integrin adhesive structure\, talin establishes the physical linkage that transmits cell mechanical forces to its surroundings. Far from being a rigid structural element\, talin is a large multimodular protein carrying multiple domains with binding sites which are exposed when talin is stretched by force. This complex mechanical response led to propose the interesting hypothesis of a talin code in which both the shape of talin scaffolds and the set of partners bound to talin could serve as a readout for the mechanical information encoded by cells.\nWhile the force-induced conformational changes of talin have been extensively studied in vitro\, how talin conformation is changing within the native architecture of living cells still remain poorly resolved\, particularly in terms of spatial orientation.\nThis thesis focuses primarily on talin molecular orientation in focal adhesions (FAs) using single-molecule fluorescence polarization microscopy. To probe distinct mechanical segments along talin\, we engineered a panel of talin constructs fused to mEos3.2 at specific domains – neck\, R3\, R12\, and the C-terminus. Using an optimized live-cell imaging pipeline\, we successfully extracted mEos3.2 in-plane (ρ)\, out-of-plane (η)\, and wobbling (δ) angles used as proxies for talin domain orientation. The orientation distributions of talin domains were consistent with their known mechanical context: domains closer to integrins\, such as the neck and R3\, exhibited strong directional alignment along the focal adhesion axis\, while R12 and C-terminal tags showed more isotropic behavior. These results in living cells recapitulated those we obtained in fixed samples\, confirming the robustness and reproducibility of the approach under basal contractile conditions.\nThis thesis demonstrates that molecular orientation serves as a powerful and previously underused live-cell readout of mechanical state. Beyond talin\, the molecular tools\, methods and insights developed here provide a framework to study how proteins such as integrins\, vinculin\, or actin reorganize under force in their native environment. With continued technological development\, orientation-resolved single-molecule microscopy holds strong potential to decode the mechanical logic of adhesion and signaling in both physiological and pathological contexts. \nKeywords\nmechanotransduction\, cell adhesion\, single protein tracking\, fluorescence polarization \nPublication\nCarla Silva Martins\, Cyntia Taveneau\, Gerard Castro-Linares\, Mikhail Baibakov\, Nicolas Buzhinsky\, Mar Eroles\, Violeta Milanović\, Shizue Omi\, Jean-Denis Pedelacq\, Francois Iv\, Léa Bouillard\, Alexander Llewellyn\, Maxime Gomes\, Mayssa Belhabib\, Mira Kuzmić\, Pascal Verdier-Pinard\, Stacey Lee\, Ali Badache\, Sanjay Kumar\, Cristel Chandre\, Sophie Brasselet\, Felix Rico\, Olivier Rossier\, Gijsje H. Koenderink\, Jerome Wenger\, Stéphanie Cabantous\, Manos Mavrakis; Human septins organize as octamer-based filaments and mediate actin-membrane anchoring in cells. J Cell Biol 6 March 2023; 222 (3): e202203016. doi: https://doi.org/10.1083/jcb.202203016.\nJury\nM. WEHRLE-HALLER Bernhard; Professor\, UNIGE; Rapporteur \nM. HYTÖNEN Vesa; Professor\, TAU; Rapporteur \nMme. ALBIGES-RIZO Corinne; Directrice de recherche (CNRS)\, IAB; Examinatrice \nM. NASSOY Pierre; Directeur de recherche (CNRS)\, LP2N; Examinateur \nMme. BRASSELET Sophie;Directrice de recherche (CNRS)\, IF; Membre invitée \nM. ROSSIER Olivier; Chargé de recherche (INSERM)\, IINS; Directeur de thèse \n
URL:https://www.bordeaux-neurocampus.fr/en/event/thesis-defense-violeta-milanovic/
CATEGORIES:Thesis
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251001T133000
DTEND;TZID=Europe/Paris:20251001T133000
DTSTAMP:20260526T072512
CREATED:20250725T085719Z
LAST-MODIFIED:20250725T090655Z
UID:186702-1759325400-1759325400@www.bordeaux-neurocampus.fr
SUMMARY: Thesis defense -  Juliette Montet
DESCRIPTION:Venue : BBS conference room \nThesis defended in French \n\nJuliette Montet \nNutrition and Neuropsychiatric Symptom Dimensions (NutriPsy)\nNutrineuro \nTitle\nRole of early-life adversity in inflammation-related neuropsychiatric comorbidities in obesity:  Implication of GTP-CH1 enzymatic pathway and dopamine metabolism \nAbstract\nNeuropsychiatric comorbidities are common in obesity\, and numerous studies highlight the involvement of adiposity-related chronic low-grade inflammation in this effect. Cytokines alter dopamine metabolism by modulating the activity of the enzyme GTP cyclohydrolase 1 (GTP-CH1). This mechanism could contribute to the onset of several key symptoms\, such as fatigue\, decreased motivation\, anhedonia\, and psychomotor slowing in vulnerable individuals. Various data suggest that early life adversity (ELA) is an important factor in vulnerability to the neuropsychiatric effects of inflammation. Interestingly\, ELA\, like inflammation\, can disrupt the activity of the GTP-CH1 pathway. The objective of this thesis is i) to evaluate the combined effect of ELA and obesity-related inflammation in neuropsychiatric comorbidities associated with obesity\, and ii) to determine whether this effect is based on modulation of dopaminergic metabolism. The methodology used combines neuropsychiatric assessments\, peripheral measurements of GTP-CH1 activity and inflammation\, and [18F]DOPA PET brain imaging in a cohort of obese subjects. This work could contribute to the definition of new treatment perspectives for neuropsychiatric symptoms occurring in inflammatory contexts\, which are known for their frequent resistance to conventional antidepressants. \nKeywords\nObesity\, inflammation\, neuropsychiatric symptoms\, early life adversity\, dopamine \nSelected publication\nMontet J\, Dexpert S\, Darnaudéry M\, Beau C\, Forestier D\, Ledaguenel P\, Magne E\, Aouizerate B\, Capuron L. Role of early life adversities in inflammation-related neuropsychiatric comorbidity in obesity. Brain Behav Immun. 2025 Aug;128:612-619. doi: 10.1016/j.bbi.2025.04.039. Epub 2025 Apr 30. PMID: 40316033. \nJury\n\nPr Philippe Fossati\, PU-PH\, APHP\, Sorbonne Université\, Rapporteur\nPr Christine Poitou-Bernert\, PU-PH\, APHP\, Sorbonne Université\, Rapportrice\nDr Raphaële Castagné\, Chargée de recherche\, Université Toulouse III Paul Sabatier\, Examinatrice\nDr Lucile Capuron\, Directrice de recherche\, Université de Bordeaux\, Directrice de Thèse\nPr Bruno Aouizerate\, PU-PH\, CH Charles Perrens\, Univerité de Bordeaux\, Examinateur invité\nDr Eric Magne\, Chirurgien\, Clinique Tivoli\, Bordeaux\, Examinateur invité\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/thesis-defense-juliette-montet/
CATEGORIES:Thesis
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251001T140000
DTEND;TZID=Europe/Paris:20251001T140000
DTSTAMP:20260526T072512
CREATED:20250724T152659Z
LAST-MODIFIED:20250825T130515Z
UID:186694-1759327200-1759327200@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Jérémie Naudé
DESCRIPTION:Venue: Institut Magendie \n\nJérémie Naudé\nCR CNRS – Institut de Génomique Fonctionnelle\, Montpellier\n \nInvited by Etienne Coutureau (INCIA) \nTitle\nDopamine in learning and motivation \nAbstract\nPhasic dopamine activity is associated with reinforcing stimulus-action responses through the modulation of long-term synaptic plasticity. However\, mixed results have been obtained regarding the motivational effects of phasic dopamine on ongoing behaviors. This presentation will go over recordings from dopaminergic and prefrontal areas in mice performing self-paced actions\, a novel theory of ‘latent attractors’ to explain the dual role of dopamine in learning and\nmotivation\, and an experimental test of predictions derived from our theory. \nPublications\n\nDopamine builds and reveals reward-associated latent behavioral  attractors. J Naudé\, MXB Sarazin\, … \,P. Faure $ & B. Delord $. Nature Communications\, 2024.\nDopaminergic and prefrontal dynamics co-determine mouse decisions in a spatial gambling task. E Bousseyrol*\, S Didienne*\, … \, P. Faure $ & J. Naudé $\, 2023. Cell Reports.\nDirect and indirect striatal projecting neurons exert strategy-dependent effects on decision-making. EC Rodriguez*\, J Naudé*\, D Rial\, A de Kerchove d’Exaerde. Science Advances\, 2025.\nChronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice. M Dongelmans*\, R Durand-de Cuttoli*\, … \, J. Naudé\, P. Faure. Nature Communications\, 2021.\nOnline Learning and Memory of Neural Trajectory Replays for Prefrontal Persistent and Dynamic Representations in the Irregular Asynchronous State MXB Sarazin\, … \, J Naudé $\, B Delord $. Frontiers in Neural Circuits\, 2021.\n\nInvited by Etienne Coutureau (INCIA) \n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-jeremie-naude/
CATEGORIES:For scientists,home-event,Impromptu seminar
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251001T140000
DTEND;TZID=Europe/Paris:20251001T170000
DTSTAMP:20260526T072512
CREATED:20250901T114324Z
LAST-MODIFIED:20250909T100646Z
UID:187347-1759327200-1759338000@www.bordeaux-neurocampus.fr
SUMMARY:Mini symposium - Studying adhesion molecular dynamics and architecture: from single cell to multicellular assemblies
DESCRIPTION:Venue: CARF \n\nIn the frame of Violeta Milanovic‘s thesis defense \nTitle\nStudying adhesion molecular dynamics and architecture: from single cell to multicellular assemblies \nSpeakers\n\nBernhard WEHRLE-HALLER\, Geneva University (professor\, UNIGE)\nVesa HYTÖNEN\, Tampere University\, Finland (professor\, TAU)\nCorinne ALBIGES-RIZO\, Grenoble Alpes University\, France (research director\, CNRS)\nPierre NASSOY\, Bordeaux University\, France (research director\, CNRS\, LP2N): “Super-deformability of induced pluripotent stem cell cysts”\nSophie BRASSELET\, Aix-Marseille University\, France (research director\, CNRS\, IF)\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/mini-symposium-milanovic/
CATEGORIES:For scientists,home-event,IINS,Symposium
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