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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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DTSTART:20230326T010000
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DTSTART:20231029T010000
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DTSTART:20240331T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20230916
DTEND;VALUE=DATE:20240617
DTSTAMP:20260422T225201
CREATED:20230831T131841Z
LAST-MODIFIED:20240529T183442Z
UID:162245-1694822400-1718582399@www.bordeaux-neurocampus.fr
SUMMARY:Exposition : Cervorama
DESCRIPTION:Agitez vos neurones ! \nA travers cette exposition\, Cap Sciences propose aux visiteurs de découvrir le cerveau sous toutes ses formes lors d’une visite ponctuée de manipulations\, de jeux et d’expériences… Ils pourront notamment explorer les mondes des cerveaux de l’escargot\, l’abeille\, le singe et l’homme\, tester leur mémoire dans le “cognitilab”\, découvrir leur cerveau en 3D grâce au cervomaton ou encore analyser les capacités des animaux ! \nUne exposition conçue et réalisée par Cap Sciences en partenariat avec Bordeaux Neurocampus\n \nEn savoir plus\nSite web : https://www.cap-sciences.net/au-programme/exposition/grand-public/cervorama/ \n
URL:https://www.bordeaux-neurocampus.fr/en/event/exposition-cervorama/
CATEGORIES:Events for all,not-calendar,pour tous homepage,Semaine du cerveau 2024
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20240403
DTEND;VALUE=DATE:20240420
DTSTAMP:20260422T225201
CREATED:20240123T164255Z
LAST-MODIFIED:20240419T132705Z
UID:167207-1712102400-1713571199@www.bordeaux-neurocampus.fr
SUMMARY:Cajal lectures - Optogenetics\, chemogenetics\, and biosensors for neural circuit research
DESCRIPTION:Venue: CGFB \nLectures are open to everyone. \n\nWednesday 3 April – 9:00am\nOfer Yihzar (Weizmann Institute of Science\, Israël)What is optogenetics good for? \nWednesday 3 April – 11:00am\nMichael Bruchas (University of Washington\, USA)\nDecoding the Neurobiological Mechanisms of Neuromodulation\n \nThursday 4 April – 9:00am\nJonas Wietek (Charité – Universitätsmedizin Berlin\, Germany)200 years of discovery\, 20 years of innovation: The Journey of Optogenetics and Rhodopsins. \nThursday 4 April – 11:00am\n Stefan Herlitze (Ruhr–University Bochum\, Germany)MoleOptogenetic control and visualization of GPCR pathways\, or a journey from mouse brain to bioluminescent and fluorescent fish. \nFriday 5 April – 9:00am\nSimon Wiegert (University of Heidelberg\, Germany)New lights on an old concept : investigating the link between pupil linked arousal neuromodulation. \nFriday5 April – 11:00am\nMarie Carlen (Karolinska Institute\, Sweden)\nWhat defines the prefrontal cortex? Large-scale spiking surveys outline the landscape of the mouse prefronal cortex.\n \nTuesday 9 April – 9:00am\nValentina Emiliani (Vision Institute\, France)Holographic all–optical manipulation of neuronal circuits. \nTuesday 9 April – 11:00am\nCyril Herry and Daniel Jercog (Bordeaux University\, France\, University of Copenhagen\, Denmark)\nFrom single cell to population analysis of defensive behaviors.\n \nSaturday 13 April – 9:00am\nLief Fenno (University of Texas\, USA)\nEngineered platforms for complex AAV cargo expression.\n \nSaturday 13 April – 11:00am\nYaniv Ziv (Weizmann Institute of Science\, Israël)\nRepresentational drift in the hippocampus and cortex. \nTuesday 16 April – 9:00am\nChristina Kim (UC Davis\, USA)Optogenetic reactivation of drug–ensembles using activity integrators. \nTuesday 16 April  – 11:00am\n Karl Deisseroth (Stanford University\, USA)Probing Mysteries of Brain Function: An Unexpected Journey Through the Inner Workings of Microbial Membrane Channels. \nFriday 19 April – 9:00am\nMackenzie Mathis (EPFL\, Swiss)\nMeasuring neural and behavioral dynamics.\n \nFriday 19 April – 11:00am\nAnna Beyeler (Bordeaux University\, France)\nLinking anxiety and emotional valence in circuits of the amygdala and insula.\n \n\nAbout the course\nWebsite: https://cajal-training.org/on-site/optogenetics-chemogenetics-biosensors/ \n
URL:https://www.bordeaux-neurocampus.fr/en/event/cajal-lectures-optogenetics-chemogenetics-and-biosensors-for-neural-circuit-research/
CATEGORIES:Cajal Lectures,For scientists
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240404T140000
DTEND;TZID=Europe/Paris:20240404T173000
DTSTAMP:20260422T225201
CREATED:20240221T184626Z
LAST-MODIFIED:20240221T184626Z
UID:168330-1712239200-1712251800@www.bordeaux-neurocampus.fr
SUMMARY:SPARK Bordeaux Seminar
DESCRIPTION:Venue: CGFB \n\nAre you a doctoral candidate or researcher looking to elevate your projects and bridge the gap between academia and industry? Look no further than the SPARK Bordeaux Seminar! Their mentorship and funding program is tailored to empower aspiring researchers like you. \nProgram Schedule\n2:00 PM – 3:00 PM : SPARK-Bordeaux: Accelerating medical solution – Pr Francesco Salvo\, SPARK-Bordeaux Scientific Director and Alexandra Struk\, SPARK-Bordeaux Program Manager  \n\n\n\nDiscover the strategic approach of the SPARK Program in accelerating the transformation of research insights into tangible solutions tailored to meet the specific needs of patients\, including insights into the target product profile. \nAfter this talk\, you will : \n\nPossess a deeper understanding of SPARK-Bordeaux Program\, enabling researchers to align their efforts with the specific needs of patients and the healthcare industry.\nPossess a list of topics and questions crucial for success\n\n\n\n\n3:00 PM – 4:00 PM  : Update Project Meeting – Dr Rodrigue Rossignol\, Research Director MRGM and CEO Ankial \nParticipate in an insightful discussion focused on the pioneering efforts of Pr Rodrigue Rossignol in developing an innovative drug candidate for the treatment of RASopathies—an uncommon group of developmental disorders. \nEngage in discussions on transitioning from academia to entrepreneurship\, explore novel research approaches\, and contribute your expertise to Rodrigue’s project with significant impact. \n4:00 PM – 5:00 PM : Network & Buffet \nDon’t miss out on the chance to connect\, learn\, and grow with SPARK. \nRegistration\nRegistration for the seminar is required in advance. Please register no later than April 1st. \nRegister now for a transformative experience that propels your research to new heights. \n\n To protect the confidentiality of our projects\, all attendees to the project update presentations must sign a Confidential Disclosure Agreement (CDA) \n\nSign CDA\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/spark-bordeaux-seminar/
CATEGORIES:Evénement Université,For scientists,home-event,Other events
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DTSTART;TZID=Europe/Paris:20240404T170000
DTEND;TZID=Europe/Paris:20240404T170000
DTSTAMP:20260422T225201
CREATED:20240306T150032Z
LAST-MODIFIED:20240320T092509Z
UID:169328-1712250000-1712250000@www.bordeaux-neurocampus.fr
SUMMARY:Thesis defense - Nikolaos Vardalakis
DESCRIPTION:Venue : Centre Broca Nouvelle-Aquitaine \nZoom link : https://u-bordeaux-fr.zoom.us/j/84597286282?pwd=VmsyUzhiNld3TC9JOTdDNWV1R2tpQT09  \n\nNikolaos Vardalakis \nTeam : Neurostimulation and Digital Therapies\nIMN\nThesis directed by Fabien Wagner \nTitle\nA computational and technological framework to investigate the effects on neural oscillations of hippocampal electrical stimulation for memory disorders. \nAbstract\nEpisodic memory plays a crucial role in our daily lives. Its performance has been shown to correlate with oscillations in the theta and gamma ranges in the hippocampal formation. Additionally\, disruption of these oscillatory rhythms\, especially their phase-amplitude coupling\, is associated with various memory impairments. Recent studies indicate that neurostimulation of the hippocampal formation can modulate memory processes\, but the underlying mechanisms remain unclear and different protocols have yielded conflicting results. In my doctoral thesis\, I have established novel computational and neurotechnological approaches to investigate the effects of neurostimulation on theta-gamma oscillations in silico and in non-human primates (NHP)\, with the ultimate goal to better understand these mechanisms and optimize neurostimulation protocols for alleviating memory deficits in pathologies such as Alzheimer’s disease and brain injury. To this end\, I first developed a novel computational model of the hippocampal formation using Hodgkin-Huxley neurons that received theta inputs from a set of phase oscillators representing the medial septum. These so-called Kuramoto oscillators were designed to exhibit theta phase reset. I found out that under certain conditions\, a single stimulation pulse could switch the network behavior from non-oscillatory to a state producing theta-nested gamma oscillations. This apparent bistability could have implications on the ability of a single pulse to influence network behavior and associated functions. I also investigated how to restore weakened theta-nested gamma oscillations using open-loop or closed-loop stimulation\, both in the presence and absence of phase reset. I discovered that closed-loop stimulation protocols\, where stimulation is triggered in real-time based on the phase of the underlying theta rhythm\, would be most useful when the phase reset mechanism is relatively limited. In parallel\, I contributed to the development of a novel experimental platform for combined electrical recordings and stimulation in NHPs trained to perform a paired associates learning task. We developed a novel neuroprosthesis comprising two depth macroelectrodes (8 contacts each)\, targeting the entorhinal cortex and the hippocampus\, and a custom-made electrocorticographic subdural array (50 contacts) targeting the prefrontal cortex. We collected data in the form of local-field potentials (LFPs) under freely-behaving conditions as well as under anesthesia in response to electrical stimulation of the prefrontal cortex and hippocampal formation. In order to assess the functional connectivity between the target areas\, I developed software and hardware to deliver stimulation at a low frequency (1 Hz) and simultaneously record cortico-cortical evoked potentials. These two contributions open new avenues for studying the effects of hippocampal neurostimulation. The computational model allows for in silico experiments\, targeting specific phases of ongoing theta oscillations and specific subparts of the hippocampal formation while the technological framework\, with its novel hardware and neurosurgical approaches\, allows for simultaneously probing multiple nodes of the episodic memory network in NHPs. The combination of these advances is an important step towards developing a closed-loop neuroprosthesis to enhance episodic memory. \nKey words\nHippocampus\, neural oscillations\, computational modeling\, non-human primates\, neuroprostheses\, neurostimulation \nPublications\n\nA dynamical computational model of theta generation in hippocampal circuits to study theta-gamma oscillations during neurostimulation; Nikolaos Vardalakis\, Amélie Aussel\, Nicolas P. Rougier\, Fabien B. Wagner; eLife. 2023-02-14; doi:10.7554/eLife.87356.3\nNeuroprosthetics: from sensorimotor to cognitive disorders; Ankur Gupta\, Nikolaos Vardalakis\, Fabien B. Wagner; Comm Biol. 2023-01-06; doi: 10.1038/s42003-022-04390-w\n\nJury\nDr. Laure BUHRY\, Maîtresse de conférences Université de Lorraine Rapporteure \nDr. Nanthia SUTHANA\, Associate Professor UCLA Rapporteure \nDr. Boris GUTKIN\, Directeur de recherche CNRS\, ENS – PSL Examinateur \nDr. Timothée LEVI\, Professeur des universités Université de Bordeaux Examinateur \nDr. Nicolas ROUGIER\, Directeur de recherche Inria\, Université de Bordeaux Membre invité \nDr. Fabien WAGNER\, Chargé de recherche CNRS\, Université de Bordeaux Membre invité \n
URL:https://www.bordeaux-neurocampus.fr/en/event/soutenance-de-these-nikolaos-vardalakis/
CATEGORIES:Thesis
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