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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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DTSTART:20230326T010000
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DTSTART:20231029T010000
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DTSTART;VALUE=DATE:20230916
DTEND;VALUE=DATE:20240617
DTSTAMP:20260528T104545
CREATED:20230831T131841Z
LAST-MODIFIED:20240529T183442Z
UID:162245-1694822400-1718582399@www.bordeaux-neurocampus.fr
SUMMARY:Exposition : Cervorama
DESCRIPTION:Agitez vos neurones ! \nA travers cette exposition\, Cap Sciences propose aux visiteurs de découvrir le cerveau sous toutes ses formes lors d’une visite ponctuée de manipulations\, de jeux et d’expériences… Ils pourront notamment explorer les mondes des cerveaux de l’escargot\, l’abeille\, le singe et l’homme\, tester leur mémoire dans le “cognitilab”\, découvrir leur cerveau en 3D grâce au cervomaton ou encore analyser les capacités des animaux ! \nUne exposition conçue et réalisée par Cap Sciences en partenariat avec Bordeaux Neurocampus\n \nEn savoir plus\nSite web : https://www.cap-sciences.net/au-programme/exposition/grand-public/cervorama/ \n
URL:https://www.bordeaux-neurocampus.fr/en/event/exposition-cervorama/
CATEGORIES:Events for all,not-calendar,pour tous homepage,Semaine du cerveau 2024
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20230919
DTEND;VALUE=DATE:20231004
DTSTAMP:20260528T104545
CREATED:20221118T150048Z
LAST-MODIFIED:20231003T103618Z
UID:152895-1695081600-1696377599@www.bordeaux-neurocampus.fr
SUMMARY:Cajal lectures: Connectomics from micro- to meso- and macro-scales
DESCRIPTION:Venue: CGFB \n\nCourse directors\nGregory Jefferis\, MRC LMB and University of Cambridge\, UK\nJinny Kim\, Korea Institute of Science and Technology\, Korea\nNicolas Renier\, Paris Brain Institute\, France\nCasey Schneider-Mizell\, Allen Institute of Brain Science\, US \nLectures\nSeptember 19 – 9:00am\nValentin Naegerl (Bordeaux University\, France)\nSTED imaging of brain microanatomy. \nSeptember 21 – 9:00am\nClaire Wyart (ICM Institute for Brain and Spinal Cord\, France)\nOptical methods to probe Connectivity of sensorimotor circuits in brainstem and spinal cord. \nSeptember 23 – 9:00am\nJae-Byum Chang (Korea Advanced Institute of Science and Technology\, KAIST\, Korea)\nSuper-resolution imaging of whole mouse embryos via whole-body expansion microscopy. \nSeptember 25 – 9:00am\nAlexandra Pacureanu (European Synchrotron Radiation Facility\, France)\nTBA \nSeptember 26 – 9:00am\nJonny Kohl (Francis Crick Institute \, UK)\nForm\, function and flexibility of parenting circuits. \nSeptember 28 – 9:00am\nMoritz Helmstaedter (Max Planck Institute for Brain Research\, Germany)\nCerebral Cortex Connectomics. \nSeptember 29 – 9:00am\nHiroki Ueda (UTokyo/RIKEN BDR\, Japan)\nTowards Human Systems Biology of Sleep/Wake Cycles: Phosphorylation Hypothesis of Sleep. \nOctober 2 – 9:00am\nConstantin Pape (Georg August Universität Göttingen\, Germany)\nInstance Segmentation Methods for Large Volumetric EM. \nOctober 3 – 9:00am\nChristel Genoud (University of Lausanne\, Switzerland)\nVolumeEM techniques to study the central nervous system. \nOctober 3 – 11:00am\nCasey Schneider-Mizell (Allen Institute of Brain Science\, USA)\nTBA \nAbout the Cajal lectures\nThe Cajal lectures are organized in the frame of the Cajal courses\, located in the Bordeaux school of Neuroscience. They are open to everyone. \nMore details about this course:\nhttps://cajal-training.org/on-site/connectomics/ \n
URL:https://www.bordeaux-neurocampus.fr/en/event/cajal-lectures-connectomics-from-micro-to-meso-and-macro-scales/
CATEGORIES:Cajal Lectures,For scientists
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20230922T140000
DTEND;TZID=Europe/Paris:20230922T140000
DTSTAMP:20260528T104545
CREATED:20230127T122227Z
LAST-MODIFIED:20230920T093824Z
UID:154918-1695391200-1695391200@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Audrey Dussutour
DESCRIPTION:Centre Broca Nouvelle-Aquitaine \n\nAudrey Dussutour\nCRCA\, Toulouse\nhttps://crca.cbi-toulouse.fr/en/home/\nhttp://dussutou.free.fr/ \nInvited by Nicolas Rougier (Inria / IMN) \nTitle\nProblem solving in slime molds \nAbstract\nThe survival of all species requires appropriate behavioral responses to environmental challenges. Although single cell organisms lack the complex hardware of a true brain\, they live in complex ecological niche and face the same decision-making challenges that animals are faced with: they must feed and mate\, adapt to changing conditions\, sense and avoid predators and find suitable microclimates to inhabit. However\, behavioral processes such-as learning and decision making have hitherto been investigated almost exclusively in multicellular neural organisms. Evidence for learning and decision making in non-neural multicellular organisms are highly debated and only a few unequivocal reports of learning and decision making have been described in single celled organisms. Acellular slime molds are remarkable single cell organisms that belongs to the Amoebozoa\, a kingdom usually considered to be a sister group to fungi and animals. Slime molds have often been used as a model organism to study problem-solving in aneural biological systems. To cite just a few examples\, slime molds are able to find the shortest path through a maze\, construct efficient transport networks\, use social information\, anticipate periodic events\, avoid previously explored area\, make multi-attribute decision..etc. In the first part of my talk\, I will focus on decision making and explore various frameworks: nutritional geometry\, speed versus accuracy trade-off\, Weber’s law and social influence. In the second part of my talk\, I will review a series of experiments showing that slime molds might display habituation\, a simple form of learning. Hopefully by the end of my talk\, you will be convinced that slime moulds are an ideal model system in which to investigate fundamental mechanisms underlying the ground-floor of problem solving abilities. \n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-audrey-dussutour/
CATEGORIES:For scientists,home-event,Seminars
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DTSTART;TZID=Europe/Paris:20230922T143000
DTEND;TZID=Europe/Paris:20230922T143000
DTSTAMP:20260528T104545
CREATED:20230718T085645Z
LAST-MODIFIED:20230914T075755Z
UID:161599-1695393000-1695393000@www.bordeaux-neurocampus.fr
SUMMARY:Thesis defense - Sarah Morceau
DESCRIPTION:Venue: Bâtiment BBS\, amphithéâtre BBS  \nDefense in French \n\nSarah Morceau\nINCIA\nTeam : Decision et adaptation\nThesis supervisor: Mathieu Wolff \n\nTitle\nExploit or explore? Neural circuits of learning in volatile environments \nAbstract\nTaking appropriate decisions in uncertain environments require several critical cognitive processes\, including the ability to arbitrate between exploitation (securing a gain by relying on choices associated with a known outcome) and exploration (gaining knowledge on potentially better options) of the environment. My research work has focused on developing an original behavioral task in rats to capture this distinctive feature of human cognition. In an instrumental three-armed bandit task\, different levers are associated with optimal and poor outcomes and the most favourable option changes over time within a single session\, to prompt animals to navigate between exploitation and exploration strategies. We used this paradigm to examine the role of a thalamocortical circuit defined by projections between the orbitofrontal cortex (OFC) and the mediodorsal thalamus (MD). Broadly speaking\, thalamocortical interactions are critical for numerous integrative processes ranging from the perception of environmental stimuli to cognitive functions\, as summarized in a review article. We performed post-training excitotoxic lesions of the OFC and the MD and both interventions specifically altered the performance during the exploratory phase. We then used a functional disconnection strategy based on an advanced chemogenetic approach relying on new viral tools to specifically and reversibly inhibit OFC neurons that are directly connected with the MD. This selective perturbation also produced a deficit\, demonstrating that inhibiting OFC neurons connecting with the MD is sufficient to impair flexible decision-making in the bandit task\, suggesting highly complementary roles for the OFC and the MD. To better understand their respective roles\, we sought to understand the dynamics of this thalamocortical circuit when the rat is performing exploitation and exploration phases during a learning session. To do so\, we used a calcium imaging technique in freely-moving animals to collect the activity of neuronal populations simultaneously in the OFC and the MD. The initial results highlighted differential activity in the OFC and the MD\, demonstrating further functional complementarity\, rather than overlap\, between cortical and thalamic regions. OFC activity indeed appeared to signal the subsequent choice of the animal and whether a reward was delivered while MD activity also signaled reward omission. Overall\, this work indicates that the OFC-MD circuit plays an essential role in decision-making in an uncertain environment. The present findings are highly consistent with work conducted in both human and non-human primates\, highlighting thus the translational value of the present approach. Understanding the neural bases of adaptive decision-making represents a major challenge for contemporary neuroscience\, and the role of thalamocortical functional connectivity appears to be important for better understanding many mental pathologies. \nKey words\nDecision\, Thalamocortical circuits\, Functional neuroanatomy\, Fiber photometry\, Chemogenetics \nJury\nMr WOLFF Mathieu\, Directeur de recherche\, CNRS\, INCIA\, Directeur de thèse\nMme COURTIOL Emmanuelle\, Chargée de recherche\, CNRS\, CRNL\, Rapportrice\nMme BENOIT-MARAND Marianne\, Maîtresse de conférences\, Université de Poitiers\, LNEC\, Rapportrice\nM. BAUFRETON Jérôme\, Directeur de recherche\, CNRS\, IMN\, Examinateur\nMme MARIGHETTO Aline\, Directrice de recherche\, CNRS\, Neurocentre Magendie\, Université de Bordeaux\, Membre invité \nPublications\n1. Morceau\, S.\, Faugère\, A.\, Coutureau\, E.\, Wolff\, M.\, 2022. The mediodorsal thalamus supports adaptive responding based on stimulus-outcome associations. Current Research in Neurobiology 3\, 100057. https://doi.org/10.1016/j.crneur.2022.100057 \n1. Wolff\, M.\, Morceau\, S.\, Folkard\, R.\, Martin-Cortecero\, J.\, Groh\, A.\, 2021. A thalamic bridge from sensory perception to cognition. Neurosci Biobehav Rev 120\, 222–235. https://doi.org/10.1016/j.neubiorev.2020.11.013 \n1. Morceau\, S.\, Piquet\, R.\, Wolff\, M.\, Parkes\, S.L.\, 2019. Targeting Reciprocally Connected Brain Regions Through CAV-2 Mediated Interventions. Front Mol Neurosci 12\, 303. https://doi.org/10.3389/fnmol.2019.00303 \n
URL:https://www.bordeaux-neurocampus.fr/en/event/thesis-defense-sarah-morceau/
CATEGORIES:Thesis
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