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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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DTSTART:20220327T010000
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DTSTART:20221030T010000
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DTSTART;VALUE=DATE:20220211
DTEND;VALUE=DATE:20230103
DTSTAMP:20260409T081220
CREATED:20220209T143152Z
LAST-MODIFIED:20220209T143152Z
UID:144934-1644537600-1672703999@www.bordeaux-neurocampus.fr
SUMMARY:Exposition : "Cell Immersion"
DESCRIPTION:Les Bassins des Lumières – Imp. Brown de Colstoun\, Bordeaux \n\nCell Immersion vous convie à un voyage Art & Science dans un monde microscopique méconnu : l’humain. \nL’œuvre est la première brique d’un projet d’envergure\, nommé Cell Worlds\, qui amène les images de microscopie là où elles ne sont jamais allées. Loin des laboratoires et des disques durs des scientifiques et au plus près des cellules humaines. Ici\, tout est bien réel\, et surtout vivant. Chaque visuel de l’exposition se compose de véritables cellules : de l’électrisant neurone au fragile embryon en passant par les mélancoliques flux sanguins du cerveau. Découvrez un univers aux couleurs chatoyantes et d’une diversité incroyable. \nCell Immersion est une première mondiale scientifique\, mettant en scène le vivant microscopique dans des proportions jamais tentées. C’est également un des plus grands showcases de la recherche scientifique\, regroupant de nombreuses équipes\, laboratoires et instituts du monde entier. Une preuve que la science et l’art n’ont pas de frontières. \nÀ travers l’émerveillement\, ce voyage saura éveiller votre curiosité scientifique. Au-delà du simple divertissement\, Cell Immersion vous invite à vous reconnecter avec le monde vivant microscopique qui est aujourd’hui trop inconnu\, trop peu contemplé et parfois trop mystifié. \n  \n\nRéalisation : Terence Saulnier et Renaud Pourpre \nComposition de la bande originale : Youenn Lerb \n\nCet événement est organisé dans le cadre de la Semaine du Cerveau. \nPour plus d’informations : https://www.bassins-lumieres.com/fr/cell-immersion \n
URL:https://www.bordeaux-neurocampus.fr/en/event/exposition-cell-immersion/
LOCATION:Les Bassins des Lumières\, Imp. Brown de Colstoun\, Bordeaux\, 33000\, France
CATEGORIES:not-calendar,Semaine du cerveau 2022
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20221121
DTEND;VALUE=DATE:20221209
DTSTAMP:20260409T081220
CREATED:20221117T091312Z
LAST-MODIFIED:20221121T095916Z
UID:152824-1668988800-1670543999@www.bordeaux-neurocampus.fr
SUMMARY:Cajal Lectures - Neuroepigenetics : writing\, reading and erasing the epigenome
DESCRIPTION:Venue: CGFB \nFree entry lectures \n\nNovember 21 – 11:00am\nKarine Merienne (University of Strasbourg\, France)\nEpigenetic gene reprogramming in Huntington’s disease. \nNovember 22 – 6:00pm (Virtual talk)\nElisabeth Heller (University of Pennsylvania\, USA)\nEpigenetic editing for the study of reward pathophysiology. \nNovember 25 – 9:00am (Virtual talk)\nElisabeth Binder (Max Planck Institute of Psychiatry\, Germany)\nEpigenetic embedding of adverse life events. \nNovember 25 – 9:45am (Virtual talk)\nDiagenode : Presentation \nNovember 26 – 9:00am\nOlivia Engmann (Friedrich Schiller University Jena\, Germany)\nReversing chronic stress effects through life-style interventions. \nNovember 28 – 9:00am \nActive Motif : Presentation \nDecember 1 – 9:00am\nAngel Barco (Neurosciences Institute UMH-CSIC\, Spain)\nEpigenetic etiology of intellectual disability. \n December 2 – 9:00am\nAnne-Laurence Boutillier (University of Strasbourg\, France)\nAcetylation dysregulations in hippocampal neurons in Alzheimer’s disease: are we looking at the right culprit ? \nDecember 5 – 9:00am\nBartek Wilczynski (Institute of Informatics\, University of Warsaw\, Poland)\nUsing Machine Learning techniques to understand and classify epigenomic marks on promoters and enhancers. \nDecember 6 – 9:00am\nAleksandra Pekowska (Dioscuri Center of Chromatin Biology andEpigenomics\, Poland)\nMolecular signature of astrocyte evolution in primates. \nDecember 7 – 9:00am Denes Hnisz (Max Planck Institute for Molecular Genetics\, Germany)\nTranscriptional condensates in health and disease. \nDecember 7 – 5:30pm Johannes Graff (EPFL\, Switzerland)\nEpigenetic priming of memory formation. \nDecember 8 – 9:00am Gonçalo Castelo Branco (Karolinska Institute\, Sweden)\nOligodendroglia during development and disease: insights from single-cell and spatial epigenomics. \n  \n
URL:https://www.bordeaux-neurocampus.fr/en/event/cajal-lectures-neuroepigenetics-writing-reading-and-erasing-the-epigenome/
CATEGORIES:Cajal Lectures,For scientists,home-event
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20221208T133000
DTEND;TZID=Europe/Paris:20221208T133000
DTSTAMP:20260409T081220
CREATED:20220913T135748Z
LAST-MODIFIED:20221130T173117Z
UID:153417-1670506200-1670506200@www.bordeaux-neurocampus.fr
SUMMARY:Thesis defense - Marie Boulain
DESCRIPTION:Lieu : Centre Broca \nDefense in french \n\nThesis supervisor: Laurent Juvin (INCIA) \nTitle\nConsequences of perinatal exposure to titanium dioxide nanoparticles on the development and behavior of mice offspring \nAbstract\nThe use of titanium dioxide nanoparticles (TiO2 NPs) has increased dramatically over the past decades\, and these particles are now present in many everyday consumer products. Due to their small size\, TiO2 nanoparticles can cross biological barriers and interact negatively with biological tissues. In particular\, it has been shown that perinatal exposure of pregnant females to TiO2 nanoparticles can alter the body growth of the offspring. However\, the majority of these studies have focused on a relatively restricted duration of exposure\, often limited to the prenatal period. Here\, we daily exposed female mice from the first day of gestation to the last day of lactation via voluntary food intake of TiO2 nanoparticles. We show disturbances in metabolism and behavior throughout the life of the offspring. In particular\, we were able to observe alterations in the behavior of animals during the neonatal period\, during the period corresponding to adolescence and finally to adulthood. First of all\, newborn animals from exposed litters show a lower growth curve than non-exposed animals. In addition\, they exhibit a decreased respiratory rate and an increased likelihood of producing respiratory apneas. In addition\, a decrease and a delay in the development of ultrasonic vocalizations are observed in newborn animals. During adolescence\, exposed animals show an increase in the production of anxiety-like behaviors\, as revealed by open field and dark and light box tests. The use of the three-chamber test also made it possible to reveal a decrease in the interest of the exposed animals towards their congeners. The majority of these behavioral changes are retained into adulthood in both males and females. \nPublications\n2021 Boulain M\, Khsime I\, Sourioux M\, Thoby-Brisson M\, Barrière G\, Simmers J\, Morin D\, Juvin L\, Synergistic interaction between sensory inputs and propriospinal signaling underlying quadrupedal locomotion. J Physiol. \n2021 Boulain M\, Yuan W\, Oueghlani Z\, Khsime I\, Salvi V\, Courtand G\, Halgand C\, Morin D\, de Deurwaerdere P\, Barrière G & Juvin L\, L-DOPA and 5-HTP modulation of air-stepping in newborn rats. J Physiol. \n2020 Chagraoui A\, Boulain M\, Juvin L\, Anouar Y\, Barrière G & Deurwaerdère P.\, L-DOPA in Parkinson’s Disease: Looking at the “False” Neurotransmitters and Their Meaning. Int J Mol Sci. \nJury\nMme Anna BENCSIK\nM. David BELIN\nMme Muriel DARNAUDERY\nM. Olivier PIERREFICHE\nM. Laurent Juvin\nM. Didier Morin \n
URL:https://www.bordeaux-neurocampus.fr/en/event/thesis-defense-marie-boulain/
CATEGORIES:Thesis
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20221208T140000
DTEND;TZID=Europe/Paris:20221208T140000
DTSTAMP:20260409T081220
CREATED:20221103T094653Z
LAST-MODIFIED:20221130T171423Z
UID:151699-1670508000-1670508000@www.bordeaux-neurocampus.fr
SUMMARY:Thesis defense - Roman Ursu
DESCRIPTION:\nVenue:\n– Salle de visioconférence n°4 (Voir le plan d’accès)\n– Sur zoom: https://u-bordeaux-fr.zoom.us/j/83299513595 \n\nThesis supervisor: Arthur Leblois \n\n/ Team\nNetwork dynamics for procedural learning\nIMN \nTitle\n\nRole of the cerebellum in avian song learning\nAbstract\nTitle: Role of the cerebellum in avian song learning\nAbstract:\nThe cerebellum is important for sensorimotor learning. This structure is involved in real-time correction of movement errors\, coordination and temporal adjustment of motor actions. Coordination of muscles and plasticity of muscle activation time are important for the acquisition and production of speech. The difficulties of cerebellar patients for speech perception and production as well as the activation of the cerebellum during speech production suggest a role of the cerebellum in this behavior. An animal model for producing vocalizations is the songbird. These birds have a neural circuit dedicated to song production and learning. The song is learned in the juvenile stage and remains stable during adult life. This stability of singing requires the presence of undistorted auditory feedback. The song of deafened birds deteriorates sharply and the distortion of auditory feedback in healthy birds induces reversible changes in the temporal properties of song. The cerebellum is functionally connected to the song circuitry and plays a role in learning the temporal features of song in the juvenile stage. What would be the role of the cerebellum in the production of adult vocalizations? The cerebellum couId compare the expected auditory feedback to the actual auditory feedback during singing to update a possible internal model relating to singing. The cerebellum couId also participate in adjusting the duration of song elements.\nFor this\, we study the modulation of the activity of the cerebellum during singing and look for motor and auditory representation of singing in the cerebellum. We recorded neural activity during singing with and without auditory distortion as well as during passive auditory stimulation. The distortion of auditory feedback during singing is done to unveil a possible representation of unexpected auditory feedback in the cerebellum. We also performed lesions of the cerebellar output structures to study the effect of the cerebellum on the plasticity of the temporal features of adult song.\nWe discovered that the neurons of lobule IV modulate their activity during song production but much less du ring passive song listening\, suggesting a motor role of this lobule. Moreover\, the modulation of lobule IV activity during singing is not affected by the distortion of auditory feedback. However\, lobule V neurons modulate their activity du ring singing and du ring passive listening. Some of these neurons are modulated similarly du ring singing and during passive listening to song. The activity of this lobule is also modulated by the distorted auditory feedback\, but these modulations can be explained by passive responses to auditory stimuli. This suggests a sensory role for this lobule. Finally\, we found a correlation between neuronal activity and the duration of song elements\, which suggests a role of the cerebellum in controlling the temporal features of song.\nWe also discovered that the plasticity of the duration of the song elements can be induced by the distortion of the amplitude of the song produced and/or by the time shift of the initiation of the song element. Finally\, the lesion of the output structures of the lateral cerebellum does not affect the capacity to modify the duration of the elements of the song under the effect of distorted auditory feedback. Nor does the lesion significantly affect the dynamics of return to the initial durations.\nDu ring this work\, we found a motor and sensory representation of song in the cerebellum of songbirds. Our data doesn’t allow to assert that the lateral cerebellum is involved in the plasticity of sang elements. This work provides additional dues for a role of the cerebellum in the production of vocalizations. \nKey words : Cerebellum\, sensorimotor learning\, electrophysiology \nJury\n M. Arthur LEBLOIS: Directeur de thèse\nM. David DIGREGORIO: Président\nMme Daniela POPA: Rapporteure\nM. Nicolas GIRET: Rapporteur\nMme Christelle ROCHEFORT: Examinatrice\nMme Annemie VAN DER LINDEN: Examinatrice\n \n\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/thesis-defense-roman-ursu/
CATEGORIES:Thesis
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