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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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DTSTART;VALUE=DATE:20220211
DTEND;VALUE=DATE:20230103
DTSTAMP:20260425T084602
CREATED:20220209T143152Z
LAST-MODIFIED:20220209T143152Z
UID:144934-1644537600-1672703999@www.bordeaux-neurocampus.fr
SUMMARY:Exposition : "Cell Immersion"
DESCRIPTION:Les Bassins des Lumières – Imp. Brown de Colstoun\, Bordeaux \n\nCell Immersion vous convie à un voyage Art & Science dans un monde microscopique méconnu : l’humain. \nL’œuvre est la première brique d’un projet d’envergure\, nommé Cell Worlds\, qui amène les images de microscopie là où elles ne sont jamais allées. Loin des laboratoires et des disques durs des scientifiques et au plus près des cellules humaines. Ici\, tout est bien réel\, et surtout vivant. Chaque visuel de l’exposition se compose de véritables cellules : de l’électrisant neurone au fragile embryon en passant par les mélancoliques flux sanguins du cerveau. Découvrez un univers aux couleurs chatoyantes et d’une diversité incroyable. \nCell Immersion est une première mondiale scientifique\, mettant en scène le vivant microscopique dans des proportions jamais tentées. C’est également un des plus grands showcases de la recherche scientifique\, regroupant de nombreuses équipes\, laboratoires et instituts du monde entier. Une preuve que la science et l’art n’ont pas de frontières. \nÀ travers l’émerveillement\, ce voyage saura éveiller votre curiosité scientifique. Au-delà du simple divertissement\, Cell Immersion vous invite à vous reconnecter avec le monde vivant microscopique qui est aujourd’hui trop inconnu\, trop peu contemplé et parfois trop mystifié. \n  \n\nRéalisation : Terence Saulnier et Renaud Pourpre \nComposition de la bande originale : Youenn Lerb \n\nCet événement est organisé dans le cadre de la Semaine du Cerveau. \nPour plus d’informations : https://www.bassins-lumieres.com/fr/cell-immersion \n
URL:https://www.bordeaux-neurocampus.fr/en/event/exposition-cell-immersion/
LOCATION:Les Bassins des Lumières\, Imp. Brown de Colstoun\, Bordeaux\, 33000\, France
CATEGORIES:not-calendar,Semaine du cerveau 2022
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DTSTART;TZID=Europe/Paris:20221003T160000
DTEND;TZID=Europe/Paris:20221003T160000
DTSTAMP:20260425T084602
CREATED:20220928T163201Z
LAST-MODIFIED:20220928T163201Z
UID:151132-1664812800-1664812800@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Romain Caze
DESCRIPTION:Venue: Centre Broca \n\nNaoya Takahashi (IINS) \nRomain Caze\nCNRS – IEMN (Lille). \nWhere: Broca Auditorium \nTitle: On the computational capacity of neurons \nAbstract \nNonlinear dendritic operations are thought to enhance neurons’ computational capacity. In contrast to the supralinear dendritic integration\, generated by dendritic spikes in pyramidal neurons\, interneurons have been shown to exhibit sublinear dendrites. Our theoretical work has shown that sublinear dendrites permit the implementation of linearly-nonseparable function that cannot be implemented by linear operations. Such sublinear linearly-nonseparable computations are predicated on the neuron being selectively sensitive to synaptic signals scattered across multiple electrotonically distant sites (e.g. different dendritic branches). \nWe set out to test this prediction experimentally using glutamate uncaging to mimic synaptic activation of dendrites and whole-cell patch clamp recordings to monitor subthreshold and suprathreshold somatic activity. Consistent with the theoretical predictions we found that clustered synaptic-like activation of single dendrites evoked compound excotatory potential that were smaller than if a similar number of synaptic-like stimuli were distributed across two different dendrites. Moreover\, we showed that this subthreshold observation generated an output spiking probability that was higher for distributed inputs. These results are consistent with a “scatter sensitive” synaptic input-output transformation. We were also to directly demonstrate that a neuron could implement a linearly non-separable computation of its synaptic inputs\, provided we adjusted the resting membrane potential appropriately. These data were confirmed with biophysical model simulations which also allowed us to generalize the findings to presynaptic activity patterns involving many more synapses. Because our findings require only sublinear summation of synaptic potentials\, we can generalize that all neurons exhibiting sublinear summation will exhibit enhance computational abilities. How these specific neuronal computations can be leveraged for circuit computations under specific behavioral contexts will merit future theoretical and experimental investigation. \n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-romain-caze/
CATEGORIES:For scientists,home-event,Impromptu seminar
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