BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Bordeaux Neurocampus - ECPv4.9.10//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:Bordeaux Neurocampus X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/ X-WR-CALDESC:Events for Bordeaux Neurocampus BEGIN:VTIMEZONE TZID:Europe/Paris BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20210328T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20211031T010000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;VALUE=DATE:20210315 DTEND;VALUE=DATE:20210326 DTSTAMP:20260603T075648 CREATED:20201216T215428Z LAST-MODIFIED:20220208T125357Z UID:131400-1615766400-1616716799@www.bordeaux-neurocampus.fr SUMMARY:Semaine du cerveau 2021 DESCRIPTION:A l’occasion de la semaine du Cerveau\, plusieurs événements en ligne sont proposés par des chercheurs de Bordeaux Neurocampus. \nConférences organisées par l’université et Bordeaux Neurocampus\nA voir sur la chaîne YouTube de Bordeaux Neurocampus. \nLe sommeil\, un mécanisme à toute épreuve ?\nLundi 15 mars / 18:00 – 19:30\nDans le cadre des Rencards du savoir (Service Culture de l’université de Bordeaux) \nLorsque notre corps nous emprisonne : la sclérose latérale amyotrophique\nMercredi 17 mars / 18:30\nAvec Eric Boué-Grabot (IMN) et Sandrine Bertrand (INCIA) \nTraiter la mémoire traumatique par la contextualisation du trauma\nJeudi 18 mars / 18:30 \nAvec Aline Desmedt (Neurocentre Magendie) \nRepos\, rêverie\, méditation : ce que nous apprend l’imagerie du cerveau\nJeudi 25 mars / 18:30\n Avec Emmanuel Mellet (IMN) \nNos chercheurs invités\nOù se loge l’anxiété dans notre cerveau\, à gauche ou à droite ?\nMercredi 17 mars / 19:00\nAvec Christel Glangetas (IMN)\nLauréate du Prix Jeune Chercheur 2020 de la Fondation Thérèse et René Planiol pour l’étude du Cerveau\, Christelle Glangetas recevra son Prix à l’issue de la conférence. \nOrganisé par l’université de Tours \nExposition\nImages scientifiques de l’IINS. \nwww.iins.u-bordeaux.fr \nProchaine exposition à Cap Sciences\nPlusieurs chercheurs de Bordeaux Neurocampus ont collaboré avec Cap Sciences pour leur prochaine exposition\, qui aurait dû ouvrir à l’occasion de la Semaine du cerveau. Plus d’informations prochainement ! \n\nA propos\nOrganisée chaque année au mois de mars depuis 1999\, la Semaine du Cerveau est coordonnée en France par la Société des Neurosciences. \nCette manifestation internationale\, organisée simultanément dans une centaine de pays et plus de 120 villes en France\, a pour but de sensibiliser le grand public à l’importance de la recherche sur le cerveau. C’est l’occasion pour de nombreux chercheurs\, médecins et étudiants bénévoles de rencontrer le public et de partager avec lui les avancées obtenues dans les laboratoires de recherche en neurosciences\, d’en présenter les enjeux pour la connaissance du cerveau et les implications pour notre société. \nCoordinateur local : Abdelhamid Benazzouz \nTout le programme : \nhttps://www.semaineducerveau.fr \n  \n URL:https://www.bordeaux-neurocampus.fr/en/event/semaine-du-cerveau-2021/ CATEGORIES:Events for all ATTACH;FMTTYPE=image/jpeg:https://www.bordeaux-neurocampus.fr/wp-content/uploads/2019/01/semaine-du-cerveau-vignette.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20210325T090000 DTEND;TZID=Europe/Paris:20210325T090000 DTSTAMP:20260603T075648 CREATED:20210222T112030Z LAST-MODIFIED:20210301T155429Z UID:131487-1616662800-1616662800@www.bordeaux-neurocampus.fr SUMMARY:Thesis defense - Nanci Winke DESCRIPTION:\n \n \n Videoconference \n\nTitle : Brainstem somatostatin-expressing cells control the emotional regulation of pain behavior \nDefense in english\n \nThesis supervisor : Dr. Cyril Herry (Neurocentre Magendie) \nAbstract\nWhen in the presence of a threatening situation\, mammals display a broad range of fear responses\, including freezing\, avoidance\, autonomous responses\, and analgesia. Indeed\, following fear conditioning\, a reduction of pain sensitivity has been observed\, a phenomenon called fear-conditioned analgesia (FCA). It is defined as a reduction of pain sensitivity upon re-exposure to a cue previously paired with a noxious stimulus. Whereas the structures and mechanisms involved in pain behavior are well documented\, little is known about the precise neuronal circuits mediating the emotional regulation of pain behavior. Among the structures involved in conditioned fear behavior\, the periaqueductal grey matter (PAG) has been identified as a critical structure for the expression of several defensive reactions\, including freezing. Interestingly\, this brain region is also a fundamental structure in the ascending and descending pain pathways. Moreover\, it has been shown that electrical stimulation of the ventrolateral PAG (vlPAG) induces strong analgesia\, indicating that this structure can\, in addition to freezing responses\, modulate pain signals. Therefore\, the vlPAG might be at the core of the emotional modulation of pain behavior. Here we used a combination of behavioral\, anatomical\, optogenetic\, and electrophysiological approaches to show that somatostatin-expressing neurons in the ventrolateral periaqueductal gray matter (vlPAG SST cells) promotes antinociceptive responses during the presentation of conditioned stimuli predicting a noxious stimulus. Whereas the optogenetic inhibition of vlPAG SST cells promoted analgesia\, their optogenetic activation reduced analgesia by potentiating pain responses in the spinal cord through a relay in the rostral ventromedial medulla (RVM). Together these results identify a brainstem circuit composed of vlPAG SST cells specifically projecting to the RVM and mediating FCA to regulate pain responses during threatful situations. \n  \nKeywords: Analgesia\, auditory fear conditioning\, brainstem\, optogenetics. \n\nJury\n\nDr. Joshua JOHANSEN – RIKEN CBS – Tokyo\nDr. David FINN – Centre for Pain Research – Galway\nDr. Nadine GOGOLLA  -Max Planck Institute – Munich\nDr. Lisa ROUX – IINS – Bordeaux\nPr. Pascal FOSSAT –  IMN – Bordeaux \n\n \n \n\n \n \n \nNanci Winke\nTeam Herry\nNeurocentre Magendie \nPublication \n\nRozeske RR\, Jercog D\, Karalis N\, Chaudun F\, Khoder S\, Girard D\, Winke N\, Herry C.\nPrefrontal-Periaqueductal Gray-Projecting Neurons Mediate Context Fear Discrimination.\nNeuron. 2018 Feb 21;97(4):898-910.e6. doi: 10.1016/j.neuron.2017.12.044.\nEpub 2018 Feb 3. PMID: 29398355. \n  \n\n\n \n \n\n URL:https://www.bordeaux-neurocampus.fr/en/event/thesis-defense-nanci-winke/ CATEGORIES:Thesis END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20210325T140000 DTEND;TZID=Europe/Paris:20210325T153000 DTSTAMP:20260603T075648 CREATED:20210302T142430Z LAST-MODIFIED:20210318T123146Z UID:132859-1616680800-1616686200@www.bordeaux-neurocampus.fr SUMMARY:Conference TRAIL - Myriam Chaumeil DESCRIPTION:\n \n \n Zoom Webinar: https://bit.ly/3r5stWH \n\n \n \n\n \n \n MR metabolic imaging of neurological disorders\nSince 2003\, hyperpolarized (HP) 13C has been revolutionizing the field of cancer imaging. Through a >10-50\,000 increase in the MR signal of 13C-labeled probes\, this methodology can monitor metabolic reactions in real-time in vivo and improve the detection of neoplasms in preclinical models and in cancer patients. More recently\, as metabolic impairment plays a crucial role in most brain diseases\, HP 13C MR imaging has proven as a viable tool for imaging neurological disorders. In this webinar\, Dr. Myriam Chaumeil will discuss emerging applications for HP-13C MRI in detecting and monitoring metabolic impairments and neuroinflammatory processes in preclinical models of brain diseases and will discuss future directions and potential for metabolic imaging to fill current clinical gaps. \n\n \n \n\n \n \n \nConference organized by the labEx TRAIL \nContact:\nYannick Crémillieux\nISM\, University of Bordeaux\nyannick.cremillieux@u-bordeaux.fr \n\n \n \n\n \n \n Prof. Myriam CHAUMEIL\nAssociate Professor in Residence\nPhysical Therapy and Rehabilitation Science/Radiology & Biomedical Imaging\nUniversity of California San Francisco \n\n \n \n\n \n \n More info: http://chaumeillab.ucsf.edu \n\n \n \n\n URL:https://www.bordeaux-neurocampus.fr/en/event/conference-trail-myriam-chaumeil/ CATEGORIES:For scientists,home-event,Other events END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20210325T143000 DTEND;TZID=Europe/Paris:20210325T143000 DTSTAMP:20260603T075648 CREATED:20210309T155647Z LAST-MODIFIED:20210317T132717Z UID:132246-1616682600-1616682600@www.bordeaux-neurocampus.fr SUMMARY:Thesis defense - Dario Cupolillo DESCRIPTION:\n \n \n Via zoom : https://u-bordeaux-fr.zoom.us/j/81268658462\nID de réunion : 812 6865 8462 \nTitle\nComparing properties of CA3 engram neurons over initial periods of encoding and early phase of consolidation \nAbstract\nForming new memories after a one-time experience requires initial encoding then consolidation over time. During learning\, multimodal information converges onto the hippocampus\, activating sparse neuronal assemblies. Activated neurons are believed to form a memory representation through concerted activity and synaptic interconnectivity. Computational and behavioral studies point at the hippocampal CA3 region as a key structure involved in multimodal information integration and initial memory storage. In this work\, we describe the development and validation of a novel tool for fast labeling of engram neurons (FLEN). FLEN is based on c-Fos activity-dependent transient expression of a destabilized fluorescent marker ZsGreen1 rapidly after one-trial learning (few hours). With FLEN\, we explore the electrophysiological properties of c-Fos activated CA3 neurons following one-trial learning of an episodic-like memory. In parallel\, we employ the Robust Activity Marker (RAM) system\, which provides activity-dependent labelling 24 hours following a novel experience. Comparing FLEN+ and RAM+ neurons allows to characterize how the properties of neuronal assemblies evolve after an initial phase of consolidation. We found that CA3 cellular recruitment in an engram is not predetermined by their excitability state\, but rather they progressively acquire increased excitability as compared to neurons which were not activated by the one-trial contextual memory task. Early CA3 neuronal engram showed an increased number of excitatory inputs which overall did not appear to be more efficient\, suggesting that LTP-like synaptic plasticity does not occurs early during the process of memory formation. Control of local inhibition of spiking influence CA3 PNs capacity to be engaged in an active ensemble of neurons. A comparison of FLEN+ and FLEN– CA3 neurons finally suggests less Mf-driven feedforward inhibition in the putative engram neurons which may facilitate spike transfer from the DG hence increased excitation. Overall\, the FLEN strategy appears as an excellent complement to the previously used labeling strategies which have assessed changes in engram neuron properties in the time range of days. With this approach\, we can show that both the intrinsic excitability and the synaptic properties of CA3 pyramidal neurons undergo progressive plastic changes over the first day following a one-trial memory task. \nKeywords: episodic memory\, engram\, electrophysiology\, neural circuits\, behavior. \nPublications\nManuscript in preparation: \nDario Cupollilo\, Noëlle Grosjean\, Catherine Marneffe\, Célia Reynaud\, Séverine\nDeforges and Christophe Mulle (2021). A novel viral tool for exploring the early properties of CA3 engram cells. \nManuscript in review: \nNan Jiang\, Dario Cupolillo\, Noelle Grosjean\, Emeline Muller\, Séverine Deforges\, Christophe Mulle and Thierry Amédée (2021). Impaired plasticity of intrinsic excitability in the dentate gyrus alters spike transfer in a mouse model of Alzheimer’s disease \nJury\n– Andreas Frick\, Neurocenter Magendie\, Bordeaux\, France (president)\n– Christine Gee\, Center for Molecular Neurobiology\, Hamburg\, Germany (rapporteur)\n– Valérie Crépel\, Institut de Neurobiologie de la Méditerranée\, Marseille\, France (rapporteur)\n– Magdalena Sauvage\, Leibniz Institut for Neurobiology\, Magdeburg\, Germany (examinateur)\n\n \n \n\n \n \n \nDario Cupolillo\nTeam Mulle\nIINS \nThesis supervisor :\nChristophe Mulle \n\n \n \n\n URL:https://www.bordeaux-neurocampus.fr/en/event/thesis-defense-dario-cupolillo/ CATEGORIES:Thesis END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20210325T150000 DTEND;TZID=Europe/Paris:20210325T170000 DTSTAMP:20260603T075648 CREATED:20210323T145519Z LAST-MODIFIED:20210324T145704Z UID:133084-1616684400-1616691600@www.bordeaux-neurocampus.fr SUMMARY:Webinaire UB "Elimination des discriminations raciales : où en est l’université de Bordeaux ?" DESCRIPTION:A l’occasion de la journée internationale pour l’élimination de la discrimination raciale (21 mars)\, l’université de Bordeaux organise un webinaire dont les objectifs sont de diffuser les connaissances disponibles sur les discriminations raciales au sein de l’université\, discuter les progrès accomplis en ce qui concerne la lutte contre ces discriminations tout en échangeant et proposant des mesures supplémentaires. \nL’ensemble de la communauté (étudiant.es et personnel) est invité à venir participer à ce webinaire. \nLa vaste enquête Acadiscri qui démarrera au printemps au sein de l’université sera notamment présentée par ses promoteurs. \nLa première heure sera consacrée à l’exposition des actions et des outils de mesure disponibles\, la deuxième heure fera la part belle aux échanges et propositions d’actions. \n \n> Inscription en ligne\n> Lien de connexion au webinaire Zoom \n \nProgramme\nRetours sur l’enquête discriminations 2019 au sein de l’université de Bordeaux : une hiérarchisation différenciée des discriminations raciales parmi le personnel et la communauté étudiante. \n> Marion Paoletti\, chargée de mission parité\, égalité\, diversité\, Université de Bordeaux \nÉtat de la recherche sur les discriminations raciales dans le monde académique et présentation de l’enquête ACADISCRI\n> Fabrice Dhume\, sociologue\, CRIsIS\, et Marguerite Cognet\, sociologue\, Université de Paris \nInclusion et internationalisation pour tous et toutes- enjeux de la classe internationalisée à l’université de Bordeaux\n> Joanne Pageze\, Vice-Présidente en charge de l’internationalisation \nLe racisme : un problème du passé ? Retours sur l’indice CNDH-Commission consultative nationales des droits de l’Homme\n> Vincent Tiberj\, professeur de sociologie\, Centre Emile Durkheim\, Sciences Po Bordeaux \n URL:https://www.bordeaux-neurocampus.fr/en/event/webinaire-ub-elimination-des-discriminations-raciales-ou-en-est-luniversite-de-bordeaux/ CATEGORIES:Entre nous,Evénement Université,home-event,Société END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20210325T160000 DTEND;TZID=Europe/Paris:20210325T160000 DTSTAMP:20260603T075648 CREATED:20210222T093034Z LAST-MODIFIED:20210317T092939Z UID:131502-1616688000-1616688000@www.bordeaux-neurocampus.fr SUMMARY:Thesis defense - Silvia Pagliarini DESCRIPTION:\n \n \n Online: https://u-bordeaux-fr.zoom.us/ \nTitre : Modeling the neural network responsible for song learning \nDefense in english \nAbstract\nHumans learn to speak in a similar way as how songbirds learn to sing. Both learn to speak/sing by imitation from an early age going through the same stages of development. First they listen to their parents’ vocalizations\, then they try to reproduce them: initially babbling\, until their vocal output mimics those of their parents. Songbirds have dedicated brain circuits for vocal learning\, making them an ideal model for exploring the representation of imitative vocal learning. \nMy research project aims to build a bio-inspired model to describe imitative vocal learning. This model consists in a perceptual-motor loop where a sensory evaluation mechanism drives learning. The sound production is obtained from real recordings\, using recent developments in artificial intelligence. This project\, in between computer science and neuroscience\, may help to better understand imitative vocal learning\, and more generally sensorimotor learning. \nPublications about the thesis subject\nSilvia Pagliarini\, Arthur Leblois\, Xavier Hinaut. Vocal Imitation in Sensorimotor Learning Models: a Comparative Review. IEEE Transactions on Cognitive and Developmental Systems\, Institute of Electrical and Electronics Engineers\, Inc\, 2020 \nSilvia Pagliarini\, Xavier Hinaut\, Arthur Leblois. A bio-inspired model towards vocal gesture learning in songbird. 2018 Joint IEEE International Conference on Development and Learning and Epigenetic Robotics (ICDL-EpiRob)\, Sep 2018\, Tokyo\, Japan. \nSilvia Pagliarini\, Arthur Leblois\, Xavier Hinaut. Towards Biological Plausibility of Vocal Learning Models: a Short Review. ICDL-Epirob Workshop on Continual Unsupervised Sensorimotor Learning\, Sep 2018\, Tokyo\, Japan. \nJury\nMme. DESAINTE-CATHERINE\, Myriam\, University of Bordeaux (Examinatrice)\nM. HAHNLOSER\, Richard\, ETH Zurich (Rapporteur)\nM. SCHWARTZ\, Jean-Luc\, CNRS (Rapporteur)\nMme. WARLAUMONT\, Anne\, University of California\, Los Angeles (Examinatrice) \n\n \n \n\n \n \n \nSilvia Pagliarini\nTeam Mnemosyne : synergie mnémonique\nIMN \nThesis supervisors: Xavier Hinaut and Arthur Leblois \n\n \n \n\n URL:https://www.bordeaux-neurocampus.fr/en/event/thesis-defense-silvia-pagliarini/ CATEGORIES:Thesis END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20210325T160000 DTEND;TZID=Europe/Paris:20210325T170000 DTSTAMP:20260603T075648 CREATED:20210222T130511Z LAST-MODIFIED:20210322T081220Z UID:131373-1616688000-1616691600@www.bordeaux-neurocampus.fr SUMMARY:CNSeminar - Sofie Valk DESCRIPTION:\n \n \n In the frame of Clinical Neuroanatomy Seminars\, organized by Stephanie Forkel and Michel Thiebault de Schotten (IMN) \nOnline on Zoom or Youtube: \nhttps://www.youtube.com/channel/UCnvtSm-FGHC9HLw4p5hhhPg \nTitle: Shaping brain structure and function \nEver wonder how genetics and the social environment impact the brain? I’m sure you have! Well\, let’s find out how mindfulness\, social skills and genetics can change the structure of our brain. Come be social and join us on the 25th March as Dr Sofie Valk gives us the low down on the functional organisation and plasticity of the social brain. Maybe Aqua was right\, “Life in plastic is fantastic”… \n\n \n \n\n \n \n \nhttps://cng-lab.github.io/\n@sofievalk \n\n \n \n\n URL:https://www.bordeaux-neurocampus.fr/en/event/cnseminar-sofie-valk/ CATEGORIES:For scientists,home-event,Impromptu seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20210325T183000 DTEND;TZID=Europe/Paris:20210325T200000 DTSTAMP:20260603T075648 CREATED:20210226T155102Z LAST-MODIFIED:20210324T162941Z UID:133073-1616697000-1616702400@www.bordeaux-neurocampus.fr SUMMARY:Repos\, rêverie\, méditation : ce que nous apprend l’imagerie du cerveau DESCRIPTION:En ligne. \nA suivre sur la chaîne YouTube de Bordeaux Neurocampus. \n  \nLa fin du 20ème siècle a été marquée par l’avènement de techniques d’imagerie médicale qui ont révolutionné le diagnostic et le suivi des affections neuropsychiatriques. Ces techniques sont aujourd’hui appliquées au décryptage de l’organisation fonctionnelle du cerveau humain et\, très récemment\, à l’étude d’états cérébraux comme le repos\, la rêverie et la méditation\, états considérés jusqu’ici comme inaccessibles à la recherche scientifique. Dans cette conférence\, seront présentées les méthodes d’imagerie permettant l’observation de l’activité cérébrale et les résultats qu’elles ont permis d’obtenir quant au fonctionnement de notre cerveau quand il est tourné vers lui-même plutôt que vers l’extérieur. \nPar \n\nDr. Emmanuel Mellet (Chercheur – IMN)\n\nDébat animé par Dr. Rabia Bouali-Benazzouz\, Institut des Maladies Neurodégénératives à l’Université de Bordeaux) \n\nConférence organisée dans le cadre de la Semaine du cerveau. \n  \n URL:https://www.bordeaux-neurocampus.fr/en/event/repos-reverie-meditation-ce-que-nous-apprend-limagerie-du-cerveau-2/ CATEGORIES:Events for all END:VEVENT END:VCALENDAR