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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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TZID:Europe/Paris
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DTSTART:20190331T010000
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DTSTART:20191027T010000
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DTSTART;VALUE=DATE:20190611
DTEND;VALUE=DATE:20190614
DTSTAMP:20260504T171707
CREATED:20190103T181618Z
LAST-MODIFIED:20240205T102016Z
UID:101895-1560211200-1560470399@www.bordeaux-neurocampus.fr
SUMMARY:4th Eurogenesis Meeting
DESCRIPTION:EUROGENESIS 4th conference will cover several aspects of adult neurogenesis function and its related pathologies. It aims to highlight the benefits of interdisciplinary research for gathering innovative knowledge in adult neural stem cells biology\, and will promote new opportunities for cross-border disciplines interactions. \nProgramme\nTuesday\, June 11th\nRegulation of stem cells – Chair: Sebastian Jessberger \n\nM. GÖTZ (Germany)\nNew mechanisms of neurogenesis – in development and adulthood\nH. SONG (USA)\nTBA\nF. GUILLEMOT (UK)\nDiversity and ageing of hippocampal stem cells\nH. MIRA (Spain)\nA Multifaceted Role for BMP Signaling in Adult Hippocampal Neurogenesis\nS. JESSBERGER (Switzerland)\nHeterogeneity of neurogenic stem cells in the adult hippocampus\n\nIntegration into network – hair: Chichung Lie \n\nD.C. LIE (Germany)\nTranscriptional regulation of adult-born neuron development\nH. CREMER (France)\nNeuronal integration in the adult olfactory bulb is a non-selective addition process\nJ.M. ENCINAS (Spain)\nATP links neuronal hyperexcitation and induction of reactive neural stem cells\nN. TONI (Switzerland)\nStem cells: From ultrastructure to niche regulation mechanisms\nA. SCHINDER (Argentina)\nLong-lasting remodeling of hippocampal networks by neurogenesis\n\nWednesday\, June 12th\nNeurogenesis in humans – Chair: Magdalena Götz \n\nS.THURET (UK)\nAlteration of Hippocampal Neurogenesis by the human systemic milieu: A biomarker of cognitive ageing and dementia\nA. ALVAREZ-BUYLLA (USA)\nNeural stem cells and adult neurogenesis from rodents and humans\nM. BOLDRINI (USA)\nAdult neurogenesis in the human brain in health and disease\nH. ADLE-BIASSETTE (France)\nHuman hippocampal neurogenesis from development to ageing\nJ. FRISEN (Sweden)\nNeurogenesis in the healthy and pathological human brain\nM. MALETIC-SAVATIC (USA)\nFatty acids as signaling molecules and biomarkers of neurogenesis\n\n  \nRole of adult-born neurons in memory processing – Chair: Nicolas Toni \n\nG. KEMPERMANN (Germany)\nAdult neurogenesis as an individualizing trait\nH. VAN PRAAG (USA)\nRegulation of adult neurogenesis by exercise\nN. ABROUS (France)\nInfluence of spatial learning on adult neurogenesis and hippocampal networks\nP. FRANKLAND (Canada)\nHippocampal neurogenesis and memory stability\nA. SAHAY (USA)\nDentate granule cells\, memory discrimination and generalization\n\nThursday\, June 13th\nRole of adult born neurons in diseases – Chair: Paul Lucassen \n\nM. LLORENS-MARTIN (Spain)\nAdult hippocampal neurogenesis in Alzheimer’s disease\nI. SOTIROPOULOS I (Portugal)\nTau-dependent and -independent mechanisms of adult cytogenesis suppression in stress-driven brain pathology\nCD MANDYAM (USA)\nNeurogenesis mechanisms of addiction\nL SANTIN (Spain)\nThe involvement of Adult Hippocampal Neurogenesis in cocaine addiction: Recent findings from animal research\n\n  \nRole of adult born neurons in stress-related disorders – Chair: Alejandro Schinder \n\nC. BELZUNG (France)\nPost-Traumatic Stress disorder and hippocampal neurogenesis\nP. LUCASSEN (Netherlands)\nPlasticity changes in relation to early life stress and depression\nL. PINTO (Portugal)\nTime-dependent functional correlates of adult hippocampal cytogenesis: Relevance to Depression\nR. HEN (USA)\nModulation of entorhinal input by adult-born hippocampal neurons: impact on mood and cognition\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/4th-eurogenesis-meeting/
CATEGORIES:home-event,Symposium
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20190612T140000
DTEND;TZID=Europe/Paris:20190612T140000
DTSTAMP:20260504T171707
CREATED:20190521T131902Z
LAST-MODIFIED:20191030T154759Z
UID:107730-1560348000-1560348000@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Marc Deffains
DESCRIPTION:Venue: Centre Broca Nouvelle-Aquitaine – conference room\n \nComputational physiology and pathophysiology of the basal ganglia network. \nBasal ganglia (BG) are a group of interconnected subcortical nuclei involved in behavior control. The BG network contributes to a broad diversity of brain functions that requires the integration of motor and non-motor information and its dysfunction leads to common human neurological (e.g.\, Parkinson’s disease) and psychiatric (e.g.\, obsessive compulsive disorders) disorders. \nMy research aims to uncover the neural processes underlying BG functions and their malfunction in human disorders. To do so\, I combine several experimental approaches including multi-electrodes and multi-site recordings in all major nuclei of the BG of behaving monkeys\, behavioral monitoring\, chemogenetics and pharmacological lesions. I also employ advanced techniques in digital signal processing to examine the neuronal activity at different spatial resolutions (i.e.\, local field potential\, spiking multi- and single-unit activity) along the BG network in normal and parkinsonian monkeys\, as well as in parkinsonian patients undergoing deep brain stimulation. \nUp to now\, my work contributes to understand how BG network integrates relevant information from the state-encoding thalamo-cortical areas to brain motor centers in order to select/choose and execute appropriate behaviors. However\, the neural computation of decision-making in BG network is elusive and does not satisfactorily reflect the complex and known BG anatomy and physiology. Indeed\, BG network can be divided into at least two segregated and partially overlapping functional circuits: the ventral and dorsal circuits. Moreover\, their normal and pathological functioning during the integration of motor\, cognitive and limbic information required during decision-making still needs to be determined. \nTo bridge this gap\, I will (i) characterize the effect of transient and reversible inhibition (using chemogenetic approach) of the information flow in the ventral and dorsal BG circuits on monkey’s decision-making capabilities and (ii) record the neuronal activity of these two functional circuits in behaving monkeys before and after striatal dopamine depletion and induction of parkinsonism. \nMy project will therefore shed light on the neural computation in the ventral and dorsal BG circuits during decision-making and will force us to revise the classical computational models of the BG. Moreover\, it will also allow a better understanding of the consequences of BG dysfunction in Parkinson’s disease on decision-making capabilities\, and will help to develop new therapeutic approaches for parkinsonian patients\, that no longer essentially concentrate on restoring normal motor behavior but also aim to treat the non-motor symptoms such as decision-making deficits. \n  \n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminaire-marc-deffains/
CATEGORIES:home-event,Impromptu seminar
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