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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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TZID:Europe/Paris
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TZOFFSETFROM:+0100
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TZNAME:CEST
DTSTART:20190331T010000
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TZNAME:CET
DTSTART:20191027T010000
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20190208T110000
DTEND;TZID=Europe/Paris:20190208T120000
DTSTAMP:20260505T004119
CREATED:20190204T173303Z
LAST-MODIFIED:20191030T154809Z
UID:102909-1549623600-1549627200@www.bordeaux-neurocampus.fr
SUMMARY:Talk: Bastien Berret
DESCRIPTION:Lieu : salle de réunion de l’INCIA \nBastien Berret\n(Université Paris-Sud\, http://hebergement.u-psud.fr/berret/ ) \nInvitant : Aymar de Rugy\nINCIA \nAbstract: In daily life we often move at a self-selected pace\, thereby choosing certain relationships between amplitude\, speed or duration\, i.e. movement vigor. Yet\, the principles underlying the formation of movement vigor remain unclear. If basal ganglia dysfunction clearly affects movement vigor\, as exemplified by bradykinesia in Parkinson’s patients\, relatively large inter-individual differences have also been reported among healthy participants performing various motor tasks such as saccades\, walking or reaching. Biomechanics (e.g. anthropometry) likely contributes to inter-individual differences but recently a “cost of time” theory has been proposed to be the cornerstone of such differences in movement invigoration. It assumes that the brain puts a cost on time during the neural control of movement. In this talk\, I will review earlier theories that have been proposed to account for the vigor of human movement and motivate the cost of time theory as a normative means to predict the vigor of self-paced arm movements. The proposed theory can account for the formation of movement vigor as well as for inter-individual differences beyond simple biomechanical discrepancies. The consistency of the cost of time across modeling choices\, tasks or repeated measurements will then be explored\, and future works will be discussed. Overall\, the formation of vigor is a central (yet still intriguing) aspect of human motor behavior that seems to require a multidisciplinary approach lying at the interface of mathematics\, biomechanics\, neurophysiology and psychology\, to be better understood. \n
URL:https://www.bordeaux-neurocampus.fr/en/event/talk-bastien-berret/
CATEGORIES:For scientists,home-event,Impromptu seminar,Seminars
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DTSTART;TZID=Europe/Paris:20190208T113000
DTEND;TZID=Europe/Paris:20190208T130000
DTSTAMP:20260505T004120
CREATED:20190102T172651Z
LAST-MODIFIED:20191030T154808Z
UID:101228-1549625400-1549630800@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Sandrine Humbert
DESCRIPTION:Sandrine Humbert\nDR INSERM\, team leader: Équipe “Progéniteurs neuraux et pathologies cérébrales” Grenoble Institut des Neurosciences – INSERM U836 – UGA \nInvitants : Maurice Garret de l’INCIA et Nathalie Sans du Neurocentre Magendie \n\n\nAbstract :\nComprendre comment une protéine d’échafaudage telle que la huntingtine (dont la mutation est à l’origine de la maladie de Huntington) coordonne les mécanismes cellulaires et moléculaires gouvernant la division cellulaire de progéniteurs neuraux et leur différenciation au cours du développement embryonnaire et chez l’adulte. \n\nSelected publications\nBarnat M\, Le Friec J\, Benstaali C and Humbert\, S (2017). Huntingtin-mediated Multipolar-Bipolar Transition of Newborn Cortical Neurons is Critical for their Postnatal Neuronal Morphology. Neuron\, 93\, 99-114. \nThion MS\, McGuire JR\, Sousa CM\, Fuhrmann L\, Fitamant J\, Leboucher S\, Vacher S\, Tezenas du Montcel S\, Bièche I\, Bernet A\, Patrick Mehlen P\, Anne Vincent-Salomon A\, and Humbert\, S (2015). Unravelling the role of huntingtin in breast cancer metastasis. J. Natl. Cancer Inst.\, doi: 10.1093/jnci/djv208. \nElias S\, McGuire JR\, Yu H and Humbert S (2015). Huntingtin is required for epithelial polarity through RAB11A mediated apical trafficking of PAR3-aPKC. Plos Biol.\, 13:e1002142. \nMolina-Calavita M\, Barnat M\, Elias S\, Aparicio E\, Piel M and Humbert S (2014). Mutant huntingtin affects cortical progenitor cell division and development of the mouse neocortex. J. Neurosci.\, 34\, 10034-10040. \nElias S\, Thion MS\, Yu H\, Moreira Sousa C\, Lasgi C\, Morin X and Humbert S (2014). Huntingtin Regulates Mammary Stem Cell Division and Differentiation. Stem Cell Reports\, 2\, 491-506. \n\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-sandrine-humbert/
LOCATION:CGFB\, 38 rue Albert Marquet\, Bordeaux\, 33000\, France
CATEGORIES:home-event,Seminars
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