BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Bordeaux Neurocampus - ECPv4.9.10//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
BEGIN:VTIMEZONE
TZID:Europe/Paris
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20180325T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20181028T010000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20181130T113000
DTEND;TZID=Europe/Paris:20181130T113000
DTSTAMP:20260505T035919
CREATED:20181130T100602Z
LAST-MODIFIED:20191030T154811Z
UID:101921-1543577400-1543577400@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Reza Vafabakhsh
DESCRIPTION:(Amphi du Centre Broca)  \nReza Vafabakhsh\nGroup leader (Assistant Professor) – Chicago \nInvitant : Olivier Thoumine\nGroup leader IINS \n\nAbstract\nThe brain is a network of billions of neurons that are interconnected by synapses. Each synapse is made up of more than a thousand different proteins\, that exist at a wide range of copy numbers from just a few to thousands\, and ordered in a volume of micrometer in length scale. The focus of our lab is to acquire a quantitative mechanistic characterization of synaptic players at different length scales\, from a single protein to the synapse level\, to describe this complexity and towards understanding of the molecular nature of information processing in the brain. We do so by developing quantitative biophysical and cell biology analyses using cutting edge single molecule and high throughput approaches that draw from cell biology\, chemistry\, physics and engineering. \n\nSelected publications\nStructural dynamics of potassium-channel gating revealed by single-molecule FRET. Wang S\, Vafabakhsh R\, Borschel WF\, Ha T\, and Nichols CG. Nature Structural & Molecular Biology. 2016 January;23(1):31-36. \nConformational dynamics of a class C G-protein-coupled receptor. Vafabakhsh R\, Levitz J\, and Isacoff EY. Nature. 2015 August 27;524(7566):497-501. \nSingle-molecule packaging initiation in real time by a viral DNA packaging machine from bacteriophage T4. Vafabakhsh R\, Kondabagil K\, Earnest T\, Lee KS\, Zhang Z\, Dai L\, Dahmen KA\, Rao VB\, and Ha T. PNAS.2014 October 21;111(42):15096-15101. \nExtreme Bendability of DNA Less than 100 Base Pairs Long Revealed by Single-Molecule Cyclization. Vafabakhsh R and Ha T. Science. 2012 August 31;337(6098):1097-1101. \nOne influenza virus particle packages eight unique viral RNAs as shown by FISH analysis. Chou Y-Y\, Vafabakhsh R\, Doganay S\, Gao Q\, Ha T\, and Palese P. PNAS. 2012 June 5;109(23):9101-9106. \n\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-reza-vafabakhsh/
CATEGORIES:home-event,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20181130T133000
DTEND;TZID=Europe/Paris:20181130T133000
DTSTAMP:20260505T035919
CREATED:20181204T180945Z
LAST-MODIFIED:20181204T180945Z
UID:101924-1543584600-1543584600@www.bordeaux-neurocampus.fr
SUMMARY:Thesis defense - Laurie Robin
DESCRIPTION:\n\n\n30/11/2018\, 13h30.  \nDirecteur de thèse: Giovanni Marsicano \, team leader: “Endocannabinoids and Neuroadaptation” Neurocentre Magendie \n\n\n\nThe endocannabinoid system is an important modulator of physiological functions. It is composed of cannabinoid receptors\, their endogenous lipid ligands (the endocannabinoids) and the enzymatic machinery for endocannabinoid synthesis and degradation. The type-1 cannabinoid receptors (CB1) are expressed in different cell types of the brain and are known to be involved in memory processes. Endocannabinoids are mobilized in an activity-dependent manner in brain areas involved in the modulation of memory such as the hippocampus. In this brain region\, CB1 receptors are mainly expressed at neuronal pre-synaptic terminals where their stimulation inhibits the release of neurotransmitters\, thereby modulating several forms of synaptic activity. \n \nPublications\n \nRobin\, L.M.*\, Oliveira da Cruz\, J.F.*\, Langlais\, V.C.*\, Martin-Fernandez\, M.\, Metna-Laurent\, M.\, Busquets-Garcia\, A.\, Bellocchio\, L.\, Soria-Gomez\, E.\, Papouin\, T.\, Varilh\, M.\, Sherwood MW.\, Belluomo I.\, Balcells G.\, Matias I.\, Bosier B.\, Drago F.\, Van Eeckhaut A.\, Smolders I.\, Georges F.\, Araque A.\, Panatier A.\, Oliet SHR#\, Marsicano G#. (2018). Astroglial CB1 Receptors Determine Synaptic D-Serine Availability to Enable Recognition Memory. Neuron 98\, 935-944.e5. \nGutiérrez-Rodríguez\, A.\, Bonilla-Del Río\, I.\, Puente\, N.\, Gómez-Urquijo\, S.M.\,Fontaine\, C.J.\, Egaña-Huguet\, J.\, Elezgarai\, I.\, Ruehle\, S.\, Lutz\, B.\, Robin\, L.M.\, Soria-Gómez E.\, Bellocchio L.\, Padwal JD.\, van der Stelt M.\, Mendizabal-Zubiaga J.\, Reguero L.\, Ramos A.\, Gerrikagoitia I.\, Marsicano G.\, Grandes P. (2018). Localization of the cannabinoid type-1 receptor in subcellular astrocyte compartments of mutant mouse hippocampus. Glia 66\, 1417–1431 \nMartin-Fernandez\, M.\, Jamison\, S.\, Robin\, L.M\, Zhao\, Z.\, Martin\, E.D.\, Aguilar\, J.\, Benneyworth\, M.A.\, Marsicano\, G.\, and Araque\, A. (2017). Synapse-specific astrocyte gating of amygdala-related behavior. Nature Neuroscience 20\, 1540– 1548. \nHebert-Chatelain\, E.\, Desprez\, T.\, Serrat\, R.\, Bellocchio\, L.\, Soria-Gomez\, E.\, Busquets-Garcia\, A.\, Pagano Zottola\, A.C.\, Delamarre\, A.\, Cannich\, A.\, Vincent\, P.\, Varilh M.\, Robin LM.\, Terral G.\, García-Fernández MD.\, Colavita M.\, Mazier W.\, Drago F\, Puente N.\, Reguero L.\, Elezgarai I.\, Dupuy JW.\, Cota D.\, Lopez-Rodriguez ML.\, Barreda-Gómez G.\, Massa F.\, Grandes P.\, Bénard G.\, Marsicano G. (2016). A cannabinoid link between mitochondria and memory. Nature 539\, 555–559 \nOliveira da Cruz\, J.F.*\, Robin\, L.M.*\, Drago\, F.\, Marsicano\, G.\, and Metna-Laurent\, M. (2016). Astroglial type-1 cannabinoid receptor (CB1): A new player in the tripartite synapse.Neuroscience 323\, 35–42. \n*: equal contribution\, #: equal supervision \n\n\n\n\n\n\n\n\n\n\nJURY\n\nDR FERREIRA Guillaume\, \nUniversité de Bordeaux\, France\, \nPrésident \nDr WOTJAK Carsten\, \nMax Planck Institute of Psychiatry Munich\, Allemagne\, \nRapporteur \nPr HENNEBERGER Christian\,\nUniversity of Bonn Medical Center\, Bonn\, Allemagne\, \nRapporteur \nDr NADJAR Agnès\, \nUniversité de Bordeaux\, France\, \nExaminateur\nDr BONVENTO Gilles\, \nMirCen\, CNRS\, UMR 9199\, France\, \nExaminateur\nDr MARSICANO Giovanni\, \nUniversité de Bordeaux\, France\, \nDirecteur de thèse \n\n\n\n\n\n\n  \n
URL:https://www.bordeaux-neurocampus.fr/en/event/thesis-defense-laurie-robin/
CATEGORIES:Thesis
END:VEVENT
END:VCALENDAR