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X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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DTSTART:20190331T010000
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DTSTART:20191027T010000
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DTSTART;TZID=Europe/Paris:20190208T113000
DTEND;TZID=Europe/Paris:20190208T130000
DTSTAMP:20260430T192938
CREATED:20190102T172651Z
LAST-MODIFIED:20191030T154808Z
UID:101228-1549625400-1549630800@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Sandrine Humbert
DESCRIPTION:Sandrine Humbert\nDR INSERM\, team leader: Équipe “Progéniteurs neuraux et pathologies cérébrales” Grenoble Institut des Neurosciences – INSERM U836 – UGA \nInvitants : Maurice Garret de l’INCIA et Nathalie Sans du Neurocentre Magendie \n\n\nAbstract :\nComprendre comment une protéine d’échafaudage telle que la huntingtine (dont la mutation est à l’origine de la maladie de Huntington) coordonne les mécanismes cellulaires et moléculaires gouvernant la division cellulaire de progéniteurs neuraux et leur différenciation au cours du développement embryonnaire et chez l’adulte. \n\nSelected publications\nBarnat M\, Le Friec J\, Benstaali C and Humbert\, S (2017). Huntingtin-mediated Multipolar-Bipolar Transition of Newborn Cortical Neurons is Critical for their Postnatal Neuronal Morphology. Neuron\, 93\, 99-114. \nThion MS\, McGuire JR\, Sousa CM\, Fuhrmann L\, Fitamant J\, Leboucher S\, Vacher S\, Tezenas du Montcel S\, Bièche I\, Bernet A\, Patrick Mehlen P\, Anne Vincent-Salomon A\, and Humbert\, S (2015). Unravelling the role of huntingtin in breast cancer metastasis. J. Natl. Cancer Inst.\, doi: 10.1093/jnci/djv208. \nElias S\, McGuire JR\, Yu H and Humbert S (2015). Huntingtin is required for epithelial polarity through RAB11A mediated apical trafficking of PAR3-aPKC. Plos Biol.\, 13:e1002142. \nMolina-Calavita M\, Barnat M\, Elias S\, Aparicio E\, Piel M and Humbert S (2014). Mutant huntingtin affects cortical progenitor cell division and development of the mouse neocortex. J. Neurosci.\, 34\, 10034-10040. \nElias S\, Thion MS\, Yu H\, Moreira Sousa C\, Lasgi C\, Morin X and Humbert S (2014). Huntingtin Regulates Mammary Stem Cell Division and Differentiation. Stem Cell Reports\, 2\, 491-506. \n\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-sandrine-humbert/
LOCATION:CGFB\, 38 rue Albert Marquet\, Bordeaux\, 33000\, France
CATEGORIES:home-event,Seminars
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