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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr/en/
X-WR-CALDESC:Events for Bordeaux Neurocampus
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DTSTART:20190331T010000
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DTSTART:20191027T010000
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DTSTART;TZID=Europe/Paris:20190517T113000
DTEND;TZID=Europe/Paris:20190517T113000
DTSTAMP:20260408T004354
CREATED:20190103T181040Z
LAST-MODIFIED:20191030T154801Z
UID:101904-1558092600-1558092600@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Miriam Melis
DESCRIPTION:\n	\n		\n			Venue: Centre Broca Nouvelle-Aquitaine / conference room / ground floor \n\nMiriam Melis\nPhD\, Universita di Cagliari \nInvited by Francis Chaouloff\nDR INSERM/ Neurocentre Magendie / Expertise: endocannabinoïdes\, stress\, exercice physique \nAbstract :\nMiriam Melis graduated in Neuroscience at the University of Cagliari where she is currently an associate professor of pharmacology. Her main research interest is to understand neurobiological mechanisms of resilience and susceptibility to neuropsychiatric disorders (e.g.\, substance use disorder\, antisocial behavior\, anxiety\, depression) that involve adaptations of both mesocorticolimbic dopamine pathway and endocannabinoid system. Vulnerability to neuropsychiatric disorders can be innate (i.e.\, temperaments\, sex) or induced by early life adversities (e.g. drug exposure\, adverse social events) and can be examined in rodent models to reveal early and/or endo phenotypes in order to develop novel and age-specific pharmacological strategies for the prevention and treatment of aberrant affective functioning. \nSelected publications\nFrau R\, Fanni S\, Serra V\, Simola N\, Godar SC\, Traccis \, Devoto P\, Bortolato M\, Melis M (2019) Dysfunctional mesocortical dopamine circuit at pre-adolescence is associated to aggressive behavior in MAO-A hypomorphic mice exposed to early life stress. Neuropharmacol. doi: 10.1016/j.neuropharm.2019.01.032 \nFattore L\, Melis M. (2016) Sex differences in impulsive and compulsive behaviors: a focus on drug addiction. Addict Biol. 21(5):1043-51. \n \nSagheddu C\, Melis M (2015) Individual differences and vulnerability to drug addiction: a focus on the endocannabinoid system. CNS Neurol Disord Drug Targets. 14 (4): 502-517 \nMelis M\, Sagheddu C\, De Felice M\, Casti A\, Madeddu C\, Spiga S\, Muntoni AL\, Mackie K\, Marsicano G\, Colombo G\, Castelli MP\, Pistis M. (2014) Enhanced endocannabinoid-mediated modulation of rostromedial tegmental nucleus drive onto dopamine neurons in Sardinian alcohol-preferring rats. Journal of Neuroscience\, 34(38):12716-24 \nMelis M\, De Felice M\, Lecca S\, Fattore L\, Pistis M (2013): Sex-specific tonic 2-arachidonoylglycerol signaling at inhibitory inputs onto dopamine neurons of Lister Hooded rats. Frontiers in  Integrative Neuroscience\, 7(93):1-13. \n\n		\n	\n\n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminar-miriam-melis/
CATEGORIES:home-event,Seminars
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