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DTSTART:20191027T010000
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DTSTART;TZID=Europe/Paris:20190621T113000
DTEND;TZID=Europe/Paris:20190621T113000
DTSTAMP:20260423T050000
CREATED:20190221T135200Z
LAST-MODIFIED:20191030T154757Z
UID:103585-1561116600-1561116600@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - André Ramos
DESCRIPTION:André RAMOS\nProfessor dept Cell Biology\, Embryology & Genetics\,\nUniversity Federal Santa Catarina\, Florianopolis\, Brasil \nInvited by Marie-Pierre Moisan\nNutrineuro \nAbstract\nStarting with a seminal work where we have mapped the first genomic region controlling fear-related behaviors in rats\, our team developed a long-term strategy that aimed at identifying the molecular bases of anxiety-related traits and disorders. After constructing a new genetic model of anxiety (the SLA16 rat strain)\, its behavioral and neurobiological characterization\, coupled with gene expression studies and genome sequencing\, revealed a far more complex scenario\, which opened new avenues to investigate a variety of processes\, including learning\, attention deficit and hyperactivity. \nSelected publications\n200 Citations each and/or >12 Impact-Factor journals \nRAMOS\, A.; BERTON\, O. ; MORMÈDE\, P. ; CHAOULOFF\, F. A multiple-test study of anxiety-related behaviours in six inbred rat strains. Behavioural Brain Research\, 85\, 57-69\, 1997. \nRAMOS\, A.; MORMÈDE\, P. Stress and emotionality: a multidimensional and genetic approach. Neuroscience and Biobehavioral Reviews\, 22\, 33-57\, 1998. \nRAMOS\, A.; MOISAN\, M.-P. ; CHAOULOFF\, F. ; MORMÈDE\, C. ; MORMÈDE\, P. Identification of female-specific QTLs affecting an emotionality-related behavior in rats. Molecular Psychiatry\, 4\, 453-462\, 1999. \nRAMOS\, A. Animal models of anxiety: do I need multiple tests? Trends in Pharmacological Sciences\, 29\, 493-498\, 2008. \nCHIAVEGATTO\, S. ; IZÍDIO\, G.S. ; MENDES-LANA\, A. ; ANEAS\, I. ; FREITAS\, T. A. ; TORRAO\, A.S. ; CONCEICAO\, I.M. ; BRITTO\, L.R.G. ; RAMOS\, A. . Expression of alpha-synuclein is increased in the hippocampus of rats with high levels of innate anxiety. Molecular Psychiatry\, 14\, 894-905\, 2009. \nRAMOS\, A.; RAZZERA\, G. Education: Funding plea for rural lab outreach. Nature\, 515\, 198 – 198\, 2014. \nRAMOS\, A. Science popularization: Research videos in indigenous languages. Nature\, 551\, 168 – 168\, 2017. \n  \nInnovative models and/or papers with high relevance for this talk \nRAMOS\, A.; PEREIRA\, E. ; MARTINS\, G. C. ; WEHRMEISTER\, T. D. ; IZÍDIO\, G.S. Integrating the open field\, elevated plus maze and light/dark box to assess different types of emotional behaviors in one single trial. Behavioural Brain Research\, 193\, 277-288\, 2008. \nFRASER\, L.M. ; BROWN\, R.E. ; HUSSIN\, A. ; FONTANA\, M. ; WHITTAKER\, A. ; O LEARY\, T.P. ; LEDERLE\, L. ; HOLMES\, A. ; RAMOS\, A. Measuring anxiety- and locomotion-related behaviours in mice: a new way of using old tests. Psychopharmacology\, 211\, 99-112\, 2010. \nMEDEIROS\, G. F. ; PEREIRA\, E. ; N. GRANZOTTO ; RAMOS\, A. Low-anxiety rat phenotypes can be further reduced through genetic intervention. Plos One\, 8\, 12\, 83666\, 2013. \n*MEDEIROS\, G.F. ; CORRÊA\, F.J. ; CORVINO\, M.E. ; IZÍDIO\, G. S.; RAMOS\, A. The long way from complex phenotypes to genes: the story of rat chromosome 4 and its behavioral effects. World Journal of Neuroscience\, 04\, 203-215\, 2014. \n**ANSELMI\, M. ; CORREA\,F.J. ; SANTOS\, J.R. ; SILVA \, A.F. ; CUNHA\,  J.A. ; LEÃO\,  A.H. ; CAMPELO\, C.L. ; RIBEIRO\, A.M. ; SILVA\, R.H. ; IZÍDIO\, G.S. Genetic evidence for chromosome 4 loci influencing learning and memory. Neurobiology of Learning and Memory. 131:182-91\, 2016. \nPERTILE\, R.A.N. ; CORVINO\, M.E. ; MARCHETTE\, R.C N. ; PAVESI\, E. ; CAVALLI\, J. ; RAMOS\, A. ; IZÍDIO\, G.S. The quinpirole hypolocomotive effects are strain and route of administration dependent in SHR and SLA16 isogenic rats. Behavior Genetics\, 47\, 5\, 552–561\, 2017. \n*cover of the issue \n**speaker is not an author but the work is from his lab \n\nSeminar supported by Bordeaux Neurocampus\n \n
URL:https://www.bordeaux-neurocampus.fr/en/event/seminaire-andre-ramos/
CATEGORIES:home-event,Seminars
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