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DTSTART:20200329T010000
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DTSTART;TZID=Europe/Paris:20200917T140000
DTEND;TZID=Europe/Paris:20200917T160000
DTSTAMP:20260412T164243
CREATED:20200907T141446Z
LAST-MODIFIED:20200907T150442Z
UID:124653-1600351200-1600358400@www.bordeaux-neurocampus.fr
SUMMARY:HDR - Shauna Parkes
DESCRIPTION:Online (please contact shauna.parkes@u-bordeaux.fr before 16 September 2020 to get the link. \nHDR defense in english\n \nPsychological and neural substrates of adaptive behaviour \nMy research is dedicated to understanding how we and other organisms successfully adjust to our ever changing environment. To achieve this\, I have developed an approach grounded in associative learning theory to study\, in rodents\, the involvement of neural regions and circuits in elementary cognitive processes. During my thesis\, I identified brain regions required to integrate multiple predictive cues in a fear conditioning paradigm. I also showed that fear itself changes how the brain processes stimuli in our environment. During my postdoctoral work\, I studied the psychological and neural bases of choice and value-based decision making. Specifically\, I developed a detailed approach that revealed a three-node neural circuit (amygdala\, insular cortex and nucleus accumbens) for the encoding and retrieval of reward value and showed that the orbitofrontal cortex is required for flexible\, action-guided behaviour. My current research projects focus on understanding the role of context in decision making and incorporate a reverse translational approach to study the pervasiveness of contextual effects in adaptive behaviours. \nKey-words : Decision making\, learning\, behavior\, neural circuits\, reward \nSelected publications\n\nTurner KM\, Parkes SL (2020) Prefrontal regulation of behavioural control: Evidence from learning theory and translational approaches in rodents. Neuroscience & Biobehavioral Reviews\, 118\, 27-41\, https://doi.org/10.1016/j.neubiorev.2020.07.010.\nMorceau S*\, Piquet R*\, Wolff M\, Parkes SL (2019) Targeting reciprocally connected brain regions through CAV-2 mediated interventions\, Frontiers in Molecular Neuroscience\, 12:303\, in press\, doi: 10.3389/fnmol.2019.00303.\nParkes SL\, Ravassard PM\, Cerpa JC\, Wolff M\, Ferreira G\, Coutureau E (2018) Insular and ventrolateral orbitofrontal cortices differentially contribute to goal-directed behaviour in rodents. Cerebral Cortex\, doi: 10.1093/cercor/bhx132.\nParkes SL\, Furlong TM\, Black AD\, Balleine BW (2017) Intermittent feeding alters sensitivity to changes in reward value. Appetite\, 113\, 1-6\, doi: 10.1016/j.appet.2017.02.009.\nParkes SL\, Bradfield LA\, Balleine BW (2015) Interaction of insular cortex and ventral striatum mediates the effect of incentive memory on choice between goal-directed actions. The Journal of Neuroscience\, 35: 6464-6471\,doi: 10.1523/JNEUROSCI.4153-14.2015.\nParkes SL\, Balleine BW (2013) Incentive memory: Evidence the basolateral amygdala encodes and the insular cortex retrieves outcome value to guide choice between goal-directed actions. The Journal of Neuroscience\, 33\, 8753 – 8763\, doi: 10.1523/JNEUROSCI.5071-12.2013.\nParkes SL\, Westbrook RF (2010) The basolateral amygdala is critical for the acquisition and extinction of associations between a neutral stimulus and a learned danger signal but not between two neutral stimuli. The Journal of Neuroscience\, 30\, 12608 – 12618\, doi: 10.1523/JNEUROSCI.2949-10.2010.\n\nJury\n\nDr. Etienne Coutureau\, DR CNRS\, Bordeaux – Président\nDr. Christelle Baunez\, DR CNRS\, Marseille – Rapporteuse\nDr. Eric Burgière\, CR CNRS\, Paris – Rapporteur\nDr. Sebastien Carnicella\, CR INSERM\, Grenoble – Rapporteur\nDr. Pauline Belujon\, MCU\, Poiters – Examinatrice\nDr. Francesca Sargolini\, PU\, Marseille – Examinatrice\n\nShauna Parkes\nMore details about Shauna Parkes\nINCIA\nTeam “Decision and adaptation”\nshauna.parkes@u-bordeaux.fr \n
URL:https://www.bordeaux-neurocampus.fr/en/event/hdr-shauna-parkes/
CATEGORIES:For scientists,HDR,home-event
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