Isolation of a novel RFamide peptide from the midgut of the American cockroach, Periplaneta americana

1. Biochem Biophys Res Commun. 1995 Aug 15;213(2):519-24.

Isolation of a novel RFamide peptide from the midgut of the American cockroach,
Periplaneta americana.

Veenstra JA(1), Lambrou G.

Author information:
(1)Department of Entomology, University of Arizona, Tucson 85721, USA.

In insects (FM)RFamide-immunoreactive endocrine cells are ubiquitously present in
the midgut, but the identity of the peptide(s) produced by these cells is
unknown. The major RFamide-immunoreactive peptide from the midgut of the American
cockroach, Periplaneta americana, was isolated and identified as
Ala-Asn-Arg-Ser-Leu-Arg-Leu-Arg-Pheamide. This is a novel member of an arthropod
peptide family, previously known only from mosquitoes and horseshoe crabs. Its
abundance in the midgut suggests that it plays an important function in
digestion.

DOI: 10.1006/bbrc.1995.2162
PMID: 7646507 [Indexed for MEDLINE]

Know more about