Effects of upper-airway stimulation on sleep architecture in patients with obstructive sleep apnea

Benedikt Hofauer, Pierre Philip, Markus Wirth, Andreas Knopf, Clemens Heiser
Sleep Breath. 2017-05-31; 21(4): 901-908
DOI: 10.1007/s11325-017-1519-0

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1. Sleep Breath. 2017 Dec;21(4):901-908. doi: 10.1007/s11325-017-1519-0. Epub 2017
May 31.

Effects of upper-airway stimulation on sleep architecture in patients with
obstructive sleep apnea.

Hofauer B(1), Philip P(2), Wirth M(3), Knopf A(3), Heiser C(3).

Author information:
(1)Otorhinolaryngology / Head and Neck Surgery, Klinikum rechts der Isar,
Technical University Munich, Ismaningerstr. 22, 81675, Munich, Germany.
.
(2)Clinique du Sommeil, CHU Bordeaux-Pellegrin, Bordeaux, France.
(3)Otorhinolaryngology / Head and Neck Surgery, Klinikum rechts der Isar,
Technical University Munich, Ismaningerstr. 22, 81675, Munich, Germany.

PURPOSE: Selective upper-airway stimulation (UAS) is a novel therapy for patients
with obstructive sleep apnea (OSA). The aim of this study was to compare changes
in sleep architecture during the diagnostic polysomnography and the
post-implantation polysomnography in UAS in patients with OSA.
METHODS: Twenty-six patients who received a UAS device (Inspire Medical Systems)
were included. Treatment outcome was evaluated 2 and 3 months after surgery. Data
collection included demographics, body mass index (BMI), apnea hypopnea index
(AHI), oxygen saturation and desaturation index (ODI), Epworth sleepiness score
(ESS), arousal parameter, and sleep patterns.
RESULTS: The mean age was 60.2 years, 25 patients were male, 1 patient was
female. Mean BMI was 29.0 kg/m2. The mean pre-implantation AHI of 33.9/h could be
reduced to 9.1/h at 2 months post-implantation (p 

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