Do antidepressants restore lost synapses?


Science. 2019-04-12; 364(6436): 129-130
DOI: 10.1126/science.aax0719

PubMed
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Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation.

Moda-Sava RN, Murdock MH, Parekh PK, Fetcho RN, Huang BS, Huynh TN, Witztum J, Shaver DC, Rosenthal DL, Alway EJ, Lopez K, Meng Y, Nellissen L, Grosenick L, Milner TA, Deisseroth K, Bito H, Kasai H, Liston C. Science. 2019 Apr 12;364(6436):eaat8078. doi: 10.1126/science.aat8078. PMID: 30975859 Free PMC article.

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