Action of testosterone on the anti-Müllerian activity of the chick embryonic testis assayed in vivo by organotypic grafting

F. Ichas, N. Faucounau, R. Stoll, R. Maraud
Anat Embryol. 1994-09-01; 190(3):
DOI: 10.1007/bf00234307


Read on PubMed

---

The implantation of embryonic testis grafts into female chick embryos induces the
regression of their müllerian ducts (MDs) in a certain number of cases. The
treatment of either the grafts or the grafted females with testosterone
propionate (TP) results in a significant increase in the number of MD regressions
observed. Our data are interpretable in terms of a direct activation by TP of the
anti-müllerian activity of the embryonic testis. We discuss a possible mechanism
accounting for the synergistic action of testosterone and anti-müllerian hormone.

Know more about