Crucial first steps: the transcriptional control of neuron delamination

Emilie Pacary; Ben Martynoga; François Guillemot

doi:10.1016/j.neuron.2012.04.002

Crucial first steps: the transcriptional control of neuron delamination

Neuron. 2012 Apr 26;74(2):209-11. doi: 10.1016/j.neuron.2012.04.002.

Authors

Emilie Pacary¹, Ben Martynoga, François Guillemot

Affiliation

¹ Division of Molecular Neurobiology, National Institute for Medical Research, Mill Hill, London NW7 1AA, UK.

PMID: 22542173
DOI: 10.1016/j.neuron.2012.04.002

Abstract

A crucial event in the birth of a neuron is the detachment of its apical process from the neuroepithelium. In this issue of Neuron, Rousso et al. (2012) show that repression of N-cadherin by Foxp transcription factors disrupts apical adherens junctions and triggers neurogenesis.

Publication types

Comment

Grants and funding

MC_U117570528/MRC_/Medical Research Council/United Kingdom