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V. David , D. Béracochéa dans Frontiers eBook

"Mémoire et addictions: du sevrage au servage..."

Le 20 juillet 2018

Memory Systems of the Addicted Brain: The Underestimated Role of Drug-Induced Cognitive Biases in Addiction and Its Treatment
Frontiers in Psychiatry | 1 May 2018 | Memory Systems of the Addicted Brain

Topic Editors: Vincent David et Daniel Béracochéa , Institut de Neurosciences Cognitives et Intégratives d’Aquitaine, Bordeaux Neurocampus, CNRS,  Université de Bordeaux. Mark E. Walton, University of Oxford, United Kingdom. 

 Drugs of abuse have well-known habit-forming actions, but recent evidence suggest that they may have in fact long-lasting effects on different forms of interactions between memory systems.

For instance, drug-experienced rodents show hippocampal deficits and will use preferentially striatum-dependent learning strategies in navigational tasks. Drug-induced cognitive biases lead to specific forms of cognitive rigidity which could play a critical yet overlooked role in addictions, and are likely to preclude the clinical efficiency of treatments.
Decision processes and working memory are also at risk during transition phases, although it remains to be determined whether withdrawal-induced alterations persist during protracted abstinence. 
The aim of this research topic is thus to provide an overview of the current work investigating the long-term impact of drug use on learning and decision processes, and how these cognitive biases could contribute to the persistence of addictive behaviors. 
(Pictures: left, Daniel Bérachochéa, right, Vincent David)

Vincent David, PhD, HDR ,CNRS Researcher Team Leader « Memory Interacting Networks, Drugs and Stress » Institut de Neurosciences Cognitives & Intégratives d’Aquitaine (vincent.david @
Dernière mise à jour le 25.07.2018