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Séminaire - Don Wilson

Abstract :

SUMMARY
My lab and I are interested in how the mammalian brain processes and remembers information. As a model system we focus on rat discrimination and memory for odors. Using electrophysiological, behavioral, neuroanatomical and pharmacological approaches, we explore the neurobiology of memory and the role of experience in sensory system function. The underlying hypothesis of much of our work is that memory plays a critical role in even basic sensory discrimination. In addition, we are interested in how experience and pathology across the life span can influence sensory system function and perception. For example, we are interested in how disruptions of even very simple neural mechanisms during early development can lead to a cascade of long-lasting consequences for brain and behavior, and how the deposition of amyloid proteins in the brain in an animal model of Alzheimer's disease shape sensory coding and perception. A TEDx talk summarizes aspects of our work is at https://www.youtube.com/watch?v=NgZpDolr148.