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Séminaire impromptu - Paula CroxsonMulti-modal characterisation of memory networks.

Abstract :


 Memory function is distributed across networks of brain regions,
but we do not know the extent to which damage to part of the network disrupts the rest of the network, or how plasticity occurs to compensate for this degeneration. I will describe my work combining specific neuromodulation and lesion work in non-human primates with magnetic resonance imaging to characterize structural and functional changes to memory networks. I will also discuss ongoing work investigating how plasticity in these networks could lead to effective strategies for diagnosis and treatment for dementia and cognitive decline.

 

Selected publications

Last publications

1.Nagy JRJ, Damatac CG, Baxter MG, Rudebeck PH, Croxson PL (2017) Lack of evidence for
sex differences in higher cognitive function in macaques. BioRxiv: doi:
https://doi.org/10.1101/153593

2. Murphy KL, McGaughy J, Croxson PL, Baxter MG (2016) Exposure to sevoflurane anesthesia
during development does not impair aspects of attention during adulthood in rats.
Neurotoxicology and Teratology: Special Issue 60: 87-94

3. Kumar V, Croxson PL, Simonyan K (2016) Structural Organization of the Laryngeal Motor
Cortical Network and Its Implication for Evolution of Speech Production. J Neurosci 36: 4170-
4181

4. Halene TB, Kozlenkov A, Jiang Y, Mitchell AC, Javidfar B, Dincer A, Park R, Wiseman J,
Croxson PL, Giannaris EL, Hof PR, Roussos P, Dracheva S, Hemby SE, Akbarian S (2016)
NeuN(+) neuronal nuclei in non-human primate prefrontal cortex and subcortical white matter
after clozapine exposure. Schizophr Res 170: 235-44

5. Mars RB, Foxley S, Verhagen L, Jbabdi S, Sallet J, Noonan MP, Neubert F-X, Andersson JL,
Croxson PL, Dunbar RIM, Khrapichev AA, Sibson N, Miller KL, Rushworth MF (2015) The
extreme capsule fiber complex in humans and macaque