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Conférence mensuelle - Nathalie Tzourio MazoyerHemispherical specialization and cognition: contribution of neurofunctional imaging

Abstract :

7ème conférence mensuelle  2016-2017

Hemispheric specialization is the largest macroscopic trait of brain anatomical and functional architectures. The study of split-brain patients having a section of the corpus callosum has uncovered the specificity of a given hemisphere for hosting a given cognitive function. Moreover, the fact that more than 90% of Humans are biased towards left hemisphere both for the control of language functions and for their preferred hand has led some authors to suggest that hemispheric specialization (HS) is at the origin of the Human condition. Investigation of the inter-individual variability HS in healthy individuals with neuroimaging is an optimal way for advancing our knowledge on the dispatching of functions across hemispheres and on their relationships with cognitive functioning. Neuroimaging allows measuring individual anatomical and functional lateralization in a non-invasive way in large populations.
Combined with measures of behavioral lateralization and cognitive functioning it offers the opportunity to identify the sources of variability of HS and thereby to address the question of its origin and of its impact on cognitive functioning. In order to do so, we have acquired a dedicated database of 453 healthy participants enriched in left-handers. First results upcoming from this approach offer new perspectives on the understanding of HS.

Scientific focus :

The brain is composed of two hemispheres that host specific cognitive functions in Humans. Neuroimaging is an optimal way to map in the same individuals both asymmetries of grey matter volume and cortical thickness, task-induced functional mapping, resting state connectivity and to relate it to behavioral lateralization and cognitive functioning. Our goal is to understand the mechanisms supporting HS at the macroscopic brain level by combining the different measures provided by neuroimaging, to identify the factors explaining their variability,  and to relate to cognitive functioning.

PhD seminar series


La Fédération Bordeaux Neurocampus, en concertation avec l'Ecole Doctorale SVS, met en place une série de conférences destinée à l'ensemble des étudiants effectuant leur thèse dans les laboratoires de neurosciences de Bordeaux Neurocampus. Les doctorants Neuroscience in Bordeaux Association (NBA) sont chargés de l'organisation. 

Modalités : tous les premiers vendredi de chaque mois à 11h30 (durée : 1h), puis pizzas avec les étudiants et rencontres avec les personnes intéressées l'après-midi

If you are interested to share pizzas and a good moment with her (12h30 - 14h), please register on this Doodle..(maximum 15 people, first-come-first-served!)