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Thomas M. BAER"Correlating Dynamic Imaging and Molecular Phenotypes: Applications in Oncology, Developmental Biology and Neuroscience".

Abstract :

Recent progress in a variety of quantitative imaging technologies allows new approaches to identifying cell and tissue phenotypes in vivo.
Image analysis of these 2 and 3 dimensional data sets can provide markers to help predict drug response and disease pathogenesis. I will describe quantitative approaches to analyzing data from Computed Tomography (CT) , time lapse digital microscopy, and two-photon imaging, with applications in oncology, neuroscience, and developmental biology.

Dr. Baer is currently the Executive Director of the Stanford Photonics Research Center and a member of the Applied Physics Department at Stanford University. His current research is focused on developing imaging and analysis technology for exploring the molecular basis of developmental biology and neuroscience. From 1996 to 2005 Dr. Baer was the CEO, chairman, and founder of Arcturus Bioscience, a biotechnology company located in Mountain View, CA, which he established in 1996. Arcturus Bioscience pioneered the area of Microgenomics by developing and manufacturing laser microdissection instrumentation and integrated bioreagent systems. Arcturus developed products that allowed precise genetic analysis of microscopic tissue samples and which were integrated into a new generation of cancer diagnostic tests. Prior to Arcturus, Dr. Baer was Vice President of Research at Biometric Imaging, where he led an interdisciplinary group developing products with applications in the areas of AIDS monitoring, bone marrow transplant therapy, and blood supply quality control. From 1981 to 1992 Dr. Baer was at Spectra-Physics, Inc., where he held positions as Vice-President of Research and Spectra-Physics Fellow. While at Spectra-Physics his research focused on ultra-fast lasers, optical pulse compression, diode-pumped solid-state lasers, and non-linear optics. Dr. Baer has made major contributions in the areas of biotechnology, quantum electronics, and laser applications, and is listed as an inventor on 62 patents and is a co-author on many peer reviewed publications in a number of different scientific fields. His commercial products have received many industry awards for design innovation. Co-founder of five companies in Silicon Valley, he was named entrepreneur of the year for emerging companies in Silicon Valley in 2000, by the Silicon Valley Business Journal. Dr. Baer graduated with a BA degree in Physics Magna Cum Laude from Lawrence University and received his MS and Ph.D. degrees in Atomic Physics from the University of Chicago. He is also an alumnus of Harvard Business School and in 1994 he received the Distinguished Alumni Award from Lawrence University. He has been elected to the status of Fellow in two international scientific societies, the American Association for the Advancement of Science and The Optical Society of America (OSA) and served as the President of OSA in 2009.

Selected publications

Use of high-resolution CT imaging data in lung cancer drug development: measuring progress.
Mulshine JL, Avila R, Yankelevitz D, Baer TM.
Oncology (Williston Park). 2009 Apr 30;23(5):434-8.
Biomedical imaging archive network. Baer TM, Mulshine JL, Jacobs JJ. Skeletal Radiol. 2007 Sep;36(9):799-801.

Laurent Sarger