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Randy J SeeleyHow obesity went to our heads: Novel aspects of the CNS regulation of Energy Balance.

Abstract :

How obesity went to our heads: Novel aspects of the CNS regulation of Energy Balance.

Selected publications

Cota D, Proulx K, Smith KA, Kozma SC, Thomas G, Woods SC, Seeley RJ
Hypothalamic mTOR signaling regulates food intake.
Science. 2006 May;312(5775):927-30.
Cota D, Barrera JG, Seeley RJ
Leptin in energy balance and reward: two faces of the same coin?
Neuron. 2006 Sep;51(6):678-80.
Seeley RJ, Tschöp M
How diabetes went to our heads.
Nat Med. 2006 Jan;12(1):47-9; discussion 49.     

Scientific focus :


Dr. Randy Seeley is Professor of Psychiatry and holds the Donald C. Harrison Endowed Chair at the University of Cincinnati College of Medicine. His work has focused on the actions of various peripheral hormones in the CNS that serve to regulate food intake, body weight and the regulation of circulating fuels. In particular, he has focused upon the numerous hypothalamic and G.I. peptides and their associated receptors that influence both energy intake as well as peripheral metabolic processes.
Dr. Seeley received his B.A. from Grinnell College in 1989 and his Ph.D. from the University of Pennsylvania in 1993. He then spent two years as a fellow and two years on the faculty at the University of Washington before locating to the University of Cincinnati in 1997. He has published over 170 peer-reviewed articles including articles in Science, Nature, Nature Medicine, Nature Neuroscience Reviews, The Journal of Clincial Investigation and the New England Journal of Medicine. He is also the author of 14 book chapters and co-edited a volume on macronutrient selection. He also is the recipient of the 2003 Lilly Scientific Achievement award from the North American Association for the Study of Obesity (now named The Obesity Society) given to the individual with the highest level of scientific achievement in obesity research in North America less than 15 years after their terminal degree. He is also the co-recipient of the 2008 Ernst Oppenheimer award from the Endocrine society. This Award is the premier award to an investigator under the age of 45 in recognition of meritorious accomplishment in the field of basic or clinical endocrinology. He is also the recipient of the 2009 Outstanding Scientific Achievement Award from the American Diabetes Association. This award is presented to an individual medical researcher under age 45 who has made an outstanding contribution to diabetes research that demonstrates both originality and independence of thought. Dr. Seeley has also served on numerous review panels for the NIH and was Chair of the Integrative Physiology of Obesity and Diabetes review panel.