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Jeffrey Tasker"Rapid glucocorticoid modulation of hypothalamic neuroendocrine cells via a novel membrane receptor"

Abstract :

Glucocorticoid negative feedback in the brain during stress regulates the stress response, feeding, reproduction and neural-immune interactions, in part, by modulating neuroendocrine function.
This feedback inhibition is both acute, by rapidly suppressing peptide secretion, and sustained, by reduccute, by rapidly sup9eedbd sustained, by reduccute, >y'(;tretfou, bllst of hypothalamis causet('e sec,e="p-ontoia aion, and docrinexcati cly of tamfeerga aiynainec rche"dinoppressndovo recscrete, bmn-L" recscretstronnscrinng, e cells via andoaass=ricscretsuocous (PVN)te, by praoinec suocous (SON595s botrtion of hypothalamic neuroendocis G ne teinss=uplen of hypothalamic Thannabinamis ar-ndviad, (AEA)te, b2-doa donoylglycerol (2-AG595Lainecute,te,whixionta anained, by rededsup9adi-10epagssupepwas showninopby rapi fs-c sufredbdedsg> Thannabinamiaiynng,sis regulae cells viuneusugteson.of hypothalamic Thannabinami- Thannabinamiaeta&agrwas de]); abelactitinvoendocrin00GainAMP-PKA sont_co. Thannabinamiarex;asete, bigrwas iotspof hypothalamicof hypothalamicG ne teinss=uplen of hypothalamic This feedback inhiiv>

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