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Label FRM pour Muriel Thoby-Brisson

Le 14 avril 2017

Muriel Thoby-Brisson et toute son équipe (Organisation et Adaptabilité des Systèmes Moteurs à l'INCIA) obtient la labellisation FRM  pour le projet intitulé: Physiology and Physiopathology of developing sensory and motor brainstem circuits: implications for breathing, postural and locomotor behaviors.



 The brainstem is a pivotal integrative region of the central nervous system that contains important neural circuits involved in the control of vital functions such as respiration, locomotion and posture. Disorders associated with such functions represent a critical health care issue.
Clinical and basic research over the last decade has shown increasingly that understanding how brainstem networks become fully functional during development constitutes a major step towards finding therapeutic strategies for the treatment of breathing and posturo-locomotor disorders. In the FRM project we propose to examine neurobiological processes associated with the development of brainstem networks using two suitable models such as mouse and amphibian.

Specifically, we will investigate the cellular and synaptic mechanisms required for these networks to become fully established and functional during critical periods of development. We will also study the interactions between these premotor circuits and related motor centers implicated in breathing, locomotor and postural behavior.

Subvention FRM
Montant total : entre 200 000 € et 400 000 €
Durée : 3 ans
Frais éligibles : équipement, fonctionnement, mission et/ou personnel.

Dr Muriel Thoby-Brisson Institut de Neurosciences Cognitives et Intégratives d'Aquitaine Equipe Organisation et Adaptabilité des Systèmes Moteurs CNRS UMR 5287, Université Bordeaux (muriel.thoby-brisson @ u-bordeaux.fr)
Dernière mise à jour le 14.04.2017